Search Results - "Hambly, R J"

Genotoxic activity in human faecal water and the role of bile acids : a study using the alkaline comet assay by VENTURI, M, HAMBLY, R. J, GLINGHAMMAR, B, RAFTER, J. J, ROWLAND, I. R

“…Human faecal waters from 35 healthy non-smoking volunteers (23 from England and 12 from Sweden) consuming their habitual diet were screened for genotoxicity by…”
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Influence of dietary components associated with high or low risk of colon cancer on apoptosis in the rat colon by Hambly, R.J., Saunders, M., Rijken, P.J., Rowland, I.R.

“…Although there is much epidemiological evidence for an interaction between diet and colorectal cancer risk, the mechanisms by which diet might protect against…”
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Influence of diets containing high and low risk factors for colon cancer on early stages of carcinogenesis in human flora-associated (HFA) rats by HAMBLY, R. J, RUMNEY, C. J, CUNNINGHAME, M, FLETCHER, J. M. E, RIJKEN, P. J, ROWLAND, I. R

“…Germ-free rats colonised with a human intestinal flora were fed diets containing high risk (HR) or low risk (LR) factors for colorectal cancer, and putative…”
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Effects of high- and low-risk diets on gut microflora-associated biomarkers of colon cancer in human flora-associated rats by Hambly, R.J, Rumney, C.J, Fletcher, J.M.E, Rijken, P.J, Rowland, I.R

“…Formulated diets associated with a high risk (HR) or low risk (LR) for colon cancer were used to assess the effect of diet on putative metabolic biomarkers in…”
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Establishment and characterisation of new cell lines from human breast tumours initially established as tumour xenografts in NMRI nude mice by HAMBLY, R. J, DOUBLE, J. A, THOMPSON, M. J, BIBBY, M. C

“…Human breast cancer cell lines are required as models for use in the understanding of breast carcinoma, and for improving the ability of cell screens to detect…”
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Aflatoxin exposure and DNA Damage in the comet assay in individuals from The Gambia, West Africa by Anderson, D., Yu, T-W., Hambly, R.J., Mendy, M., Wild, C.P.

“…The single cell gel electrophoresis assay (Comet assay) was used to measure DNA damage in peripheral lymphocytes from a group of individuals from The Gambia in…”
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The effect of potassium diazoacetate on human peripheral lymphocytes, human adenocarcinoma colon caco-2 cells, and rat primary colon cells in the comet assay by Anderson, Diana, Hambly, Richard J., Yu, Tian-Wei, Thomasoni, Federica, Shuker, David E.G.

“…In previous studies, N‐(N′‐acetyl‐L‐propyl)‐N‐nitrosoglycine (APNG) has been shown to be a potent mutagen in a variety of genotoxicity assays and a carcinogen…”
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CREATION OF A BLOOD DAMAGE EVALUATION "HANDBOOK" - A SUITE OF IN VITRO HAEMOCOMPATIBILITY TESTS FOR VENTRICULAR ASSIST DEVICES by Pieper, I L, Chan, C HH, Hambly, R J, Radley, G N, Jones, A, Hawkins, K M, Foster, G D, Thornton, C A

“…Aim: Our goal is to develop a comprehensive suite of blood damage testing methods that together amount to a handbook for the assessment of the overall in vitro…”
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Effects of iron salts and haemosiderin from a thalassaemia patient on oxygen radical damage as measured in the comet assay by Anderson, D., Yardley-Jones, A., Hambly, R.J., Vives-Bauza, C., Smykatz-Kloss, V., Chua-anusorn, W., Webb, J.

“…Thalassaemia is a group of genetic diseases where haemoglobin synthesis is impaired. This chronic anaemia leads to increased dietary iron absorption, which…”
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Influence of diets containing high and low risk factors for colon cancer on early stages of carcinogenesis in human flora-associated (HFA) rats by Hambly, R J, Rumney, C J, Cunninghame, M, Fletcher, JME, Rijken, P J, Rowland, IR

“…Germ-free rats colonised with a human intestinal flora were fed diets containing high risk (HR) or low risk (LR) factors for colorectal cancer, and putative…”
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