Search Results - "Hamann, Jens C."

Entosis Is Induced by Glucose Starvation by Hamann, Jens C., Surcel, Alexandra, Chen, Ruoyao, Teragawa, Carolyn, Albeck, John G., Robinson, Douglas N., Overholtzer, Michael

“…Entosis is a mechanism of cell death that involves neighbor cell ingestion. This process occurs in cancers and promotes a form of cell competition, where…”
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Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability by Mutvei, Anders P., Nagiec, Michal J., Hamann, Jens C., Kim, Sang Gyun, Vincent, C. Theresa, Blenis, John

“…The kinase mTOR complex 1 (mTORC1) promotes cellular growth and is frequently dysregulated in cancers. In response to nutrients, mTORC1 is activated on…”
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Mitosis can drive cell cannibalism through entosis by Durgan, Joanne, Tseng, Yun-Yu, Hamann, Jens C, Domart, Marie-Charlotte, Collinson, Lucy, Hall, Alan, Overholtzer, Michael, Florey, Oliver

“…Entosis is a form of epithelial cell cannibalism that is prevalent in human cancer, typically triggered by loss of matrix adhesion. Here, we report an…”
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RIPK1-mediated induction of mitophagy compromises the viability of extracellular-matrix-detached cells by Hawk, Mark A., Gorsuch, Cassandra L., Fagan, Patrick, Lee, Chan, Kim, Sung Eun, Hamann, Jens C., Mason, Joshua A., Weigel, Kelsey J., Tsegaye, Matyas Abel, Shen, Luqun, Shuff, Sydney, Zuo, Junjun, Hu, Stephan, Jiang, Lei, Chapman, Sarah, Leevy, W. Matthew, DeBerardinis, Ralph J., Overholtzer, Michael, Schafer, Zachary T.

“…For cancer cells to survive during extracellular matrix (ECM) detachment, they must inhibit anoikis and rectify metabolic deficiencies that cause non-apoptotic…”
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Entosis Controls a Developmental Cell Clearance in C. elegans by Lee, Yongchan, Hamann, Jens C., Pellegrino, Mark, Durgan, Joanne, Domart, Marie-Charlotte, Collinson, Lucy M., Haynes, Cole M., Florey, Oliver, Overholtzer, Michael

“…Metazoan cell death mechanisms are diverse and include numerous non-apoptotic programs. One program called entosis involves the invasion of live cells into…”
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Entosis enables a population response to starvation by Hamann, Jens C, Overholtzer, Michael

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