Search Results - "Hamaguchi, Kiyomi"

Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea by Tateya, Tomoko, Imayoshi, Itaru, Tateya, Ichiro, Hamaguchi, Kiyomi, Torii, Hiroko, Ito, Juichi, Kageyama, Ryoichiro

“…Mechanosensory hair cells and supporting cells develop from common precursors located in the prosensory domain of the developing cochlear epithelium…”
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Characteristics of oral squamous cell carcinoma focusing on cases unaffected by smoking and drinking: A multicenter retrospective study by Harada, Hiroyuki, Kikuchi, Masahiro, Asato, Ryo, Hamaguchi, Kiyomi, Tamaki, Hisanobu, Mizuta, Masanobu, Hori, Ryusuke, Kojima, Tsuyoshi, Honda, Keigo, Tsujimura, Takashi, Kumabe, Yohei, Ichimaru, Kazuyuki, Kitani, Yoshiharu, Ushiro, Koji, Kitamura, Morimasa, Shinohara, Shogo, Omori, Koichi

“…Background Some oral squamous cell carcinoma (OSCC) cases are unaffected by smoking or drinking. This study aimed to clarify distinctive groups among OSCC…”
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Real-time imaging of head and neck squamous cell carcinomas using confocal micro-endoscopy and applicable dye: A preliminary study by Shinohara, Shogo, Funabiki, Kazuo, Kikuchi, Masahiro, Takebayashi, Shinji, Hamaguchi, Kiyomi, Hara, Shigeo, Yamashita, Daisuke, Imai, Yukihiro, Mizoguchi, Akira

“…Confocal laser endomicroscopy (CLE) is a technology that enables microscopic visualization of lesions in real-time (optical biopsy) and has been successfully…”
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Bone Marrow Stromal Cells Accelerate Hearing Recovery via Regeneration or Maintenance of Cochlear Fibrocytes in Mouse Spiral Ligaments by Kada, Shinpei, Hamaguchi, Kiyomi, Ito, Juichi, Omori, Koichi, Nakagawa, Takayuki

“…ABSTRACT Mammalian cochleae have limited capacity for regeneration, which is one of the major difficulties in the treatment of sensorineural hearing loss. In…”
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Effects of COVID-19 pandemic on hospital visit of head and neck cancer patients by Hamaguchi, Kiyomi, Shinohara, Shogo, Michida, Tetsuhiko, Yasumoto, Mami, Hamamoto, Ayami, Yamamoto, Tomoko, Ueda, Keishi, Nakamura, Eugene

“…Head and neck cancer (HNC) often causes respiratory symptoms, so diagnostic delays due to COVID-19 are anticipated. Especially, our institute is a designated…”
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Topical insulin-like growth factor 1 treatment using gelatin hydrogels for glucocorticoid-resistant sudden sensorineural hearing loss: a prospective clinical trial by Nakagawa, Takayuki, Sakamoto, Tatsunori, Hiraumi, Harukazu, Kikkawa, Yayoi S, Yamamoto, Norio, Hamaguchi, Kiyomi, Ono, Kazuya, Yamamoto, Masaya, Tabata, Yasuhiko, Teramukai, Satoshi, Tanaka, Shiro, Tada, Harue, Onodera, Rie, Yonezawa, Atsushi, Inui, Ken-ichi, Ito, Juichi

“…Sudden sensorineural hearing loss (SSHL) is a common condition in which patients lose the hearing in one ear within 3 days. Systemic glucocorticoid treatments…”
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Neck Dissection for Cervical Lymph Node Metastases from Remote Primary Malignancies by Shinohara, Shogo, Harada, Hiroyuki, Kikuchi, Masahiro, Takebayashi, Shinji, Hamaguchi, Kiyomi

“…: Patients with cervical lymph node metastases from remote primary tumours have poor prognoses because of the advanced stage of their cancer. Owing to recent…”
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Cells transplanted onto the surface of the glial scar reveal hidden potential for functional neural regeneration by Sekiya, Tetsuji, Matthew C. Holley, Kento Hashido, Kazuya Ono, Koichiro Shimomura, Rie T. Horie, Kiyomi Hamaguchi, Atsuhiro Yoshida, Tatsunori Sakamoto, Juichi Ito

“…Significance Cell transplantation can restore function in neurodegenerative disorders, but the low rate of functional integration of donor cells into host is a…”
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Clinicopathological Characteristics and Survival Outcomes of Patients with Buccal Squamous Cell Carcinoma: Results of a Multi-Institutional Study by Shinohara, Shogo, Kikuchi, Masahiro, Harada, Hiroyuki, Hamaguchi, Kiyomi, Asato, Ryo, Tamaki, Hisanobu, Mizuta, Masanobu, Hori, Ryusuke, Kojima, Tsuyoshi, Honda, Keigo, Tsujimura, Takashi, Kumabe, Yohei, Ichimaru, Kazuyuki, Kitani, Yoshiharu, Ushiro, Koji, Omori, Koichi

“…: To investigate clinicopathological characteristics and survival outcomes of patients with buccal cancer in Japan. : This study was conducted using a database…”
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Concurrent Chemoradiotherapy With Weekly Low-Dose Cisplatin for Japanese Patients With Head and Neck Squamous Cell Carcinoma by Shinohara, Shogo, Takebayashi, Shinji, Hamaguchi, Kiyomi, Michida, Tetsuhiko, Tobe, Yota, Ikenaga, Tadashi, Yasumoto, Mami, Hamamoto, Ayami, Imagumbai, Toshiyuki, Mitsuyoshi, Takamasa, Ashida, Ryo, Iwai, Takahiro, Okabayashi, Shun

“…Background: Concurrent chemoradiotherapy (CCRT) with tri-weekly high-dose cisplatin (HDC) is considered the standard regimen. However, due to significant…”
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Lingual Lymph Node Metastases as a Prognostic Factor in Oral Squamous Cell Carcinoma-A Retrospective Multicenter Study by Kikuchi, Masahiro, Harada, Hiroyuki, Asato, Ryo, Hamaguchi, Kiyomi, Tamaki, Hisanobu, Mizuta, Masanobu, Hori, Ryusuke, Kojima, Tsuyoshi, Honda, Keigo, Tsujimura, Takashi, Kumabe, Yohei, Ichimaru, Kazuyuki, Kitani, Yoshiharu, Ushiro, Koji, Kitamura, Morimasa, Shinohara, Shogo, Omori, Koichi

“…The epidemiology and prognostic role of lingual lymph node (LLN) metastasis in patients with oral squamous cell carcinoma (OSCC) remain unclear. Here, we aimed…”
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Role of PGE-type receptor 4 in auditory function and noise-induced hearing loss in mice by Hamaguchi, Kiyomi, Yamamoto, Norio, Nakagawa, Takayuki, Furuyashiki, Tomoyuki, Narumiya, Shuh, Ito, Juichi

“…This study explored the physiological roles of PGE-type receptor 4 (EP4) in auditory function. EP4-deficient mice exhibited slight hearing loss and a reduction…”
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Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner ear by Hori, Ryusuke, Nakagawa, Takayuki, Yamamoto, Norio, Hamaguchi, Kiyomi, Ito, Juichi

“…The physiological effects of prostaglandin E1 (PGE1) and prostaglandin E2 (PGE2) are mediated by the prostaglandin E receptor subtypes EP1, EP2, EP3, and EP4,…”
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Vertebral artery injury caused by glass remnants in the neck: A case report by Mizuno, Keisuke, Shinohara, Shogo, Omura, Yoshihiro, Imamura, Hirotoshi, Shigeyasu, Masashi, Michida, Tetsuhiko, Hamaguchi, Kiyomi, Takebayashi, Shinji, Fujiwara, Keizo, Naito, Yasushi

“…Vertebral artery (VA) injuries following trauma to the neck are uncommon. We treated a case of VA injury in an 82-year-old man presented to a hospital with…”
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Prostaglandin E receptor subtype EP4 agonist serves better to protect cochlea than prostaglandin E1 by Hori, Ryusuke, Nakagawa, Takayuki, Yamamoto, Norio, Hamaguchi, Kiyomi, Ito, Juichi

“…Abstract Objective The present study aimed to examine whether an E-prostanoid receptor 4 (EP4) agonist has superior protective effects to those of…”
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Clinical significance of tumor‐associated immune cells in patients with oral squamous cell carcinoma by Kikuchi, Masahiro, Yamashita, Daisuke, Hara, Shigeo, Takebayashi, Shinji, Hamaguchi, Kiyomi, Mizuno, Keisuke, Omori, Koichi, Shinohara, Shogo

“…Background The expression of PD‐L1 in tumor cells and infiltration of tumor‐associated immune cells (TAICs) might reflect the tumor biology of head and neck…”
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Modified method for tracheoesophageal fistula closure in intractable cases by Suehiro, Atsushi, Honda, Keigo, Kishimoto, Yo, Iwanaga, Ken, Fujimura, Shintaro, Kawai, Yoshitaka, Kojima, Tsuyoshi, Hamaguchi, Kiyomi, Omori, Koichi

“…Tracheoesophageal puncture (TEP) is one of the most established methods for voice reacquisition following total laryngectomy. The most difficult complication…”
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Impact of cervical lymph node metastasis on transoral surgery for hypopharyngeal squamous cell carcinoma: A retrospective multicenter study by Ushiro, Koji, Watanabe, Yoshiki, Kishimoto, Yo, Kawai, Yoshitaka, Fujimura, Shintaro, Asato, Ryo, Tsujimura, Takashi, Hori, Ryusuke, Kumabe, Yohei, Yasuda, Kaori, Tamaki, Hisanobu, Iki, Takehiro, Kitani, Yoshiharu, Kurata, Keisuke, Kojima, Tsuyoshi, Takata, Kuniaki, Kada, Shinpei, Takebayashi, Shinji, Shinohara, Shogo, Hamaguchi, Kiyomi, Miyazaki, Masakazu, Ikenaga, Tadashi, Maetani, Toshiki, Harada, Hiroyuki, Haji, Tomoyuki, Omori, Koichi

“…Background Hypopharyngeal carcinoma is likely to spread to the lymph nodes, but there is no established strategy for management in transoral surgery. Methods…”
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Local recurrence and metachronous multiple cancers after transoral nonrobotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study by Ushiro, Koji, Watanabe, Yoshiki, Kishimoto, Yo, Kawai, Yoshitaka, Fujimura, Shintaro, Asato, Ryo, Tsujimura, Takashi, Hori, Ryusuke, Kumabe, Yohei, Yasuda, Kaori, Tamaki, Hisanobu, Iki, Takehiro, Kitani, Yoshiharu, Kurata, Keisuke, Kojima, Tsuyoshi, Takata, Kuniaki, Kada, Shinpei, Takebayashi, Shinji, Shinohara, Shogo, Hamaguchi, Kiyomi, Miyazaki, Masakazu, Ikenaga, Tadashi, Maetani, Toshiki, Harada, Hiroyuki, Haji, Tomoyuki, Omori, Koichi

“…Background Late laryngopharyngeal cancers after transoral surgery include not only local recurrences but also metachronous multiple cancers. Methods We…”
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Therapeutic potential of a gamma-secretase inhibitor for hearing restoration in a guinea pig model with noise-induced hearing loss by Tona, Yosuke, Hamaguchi, Kiyomi, Ishikawa, Masaaki, Miyoshi, Takushi, Yamamoto, Norio, Yamahara, Kohei, Ito, Juichi, Nakagawa, Takayuki

“…Notch signaling plays a crucial role in the fate determination of cochlear progenitor cells, hair cells, and supporting cells in the developing cochlea. Recent…”
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