Search Results - "Halverson, Brayden J"

Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors by Montoya, Alba L., Glavatskikh, Marta, Halverson, Brayden J., Yuen, Lik Hang, Schüler, Herwig, Kireev, Dmitri, Franzini, Raphael M.

“…DNA-encoded chemical libraries (DECLs) interrogate the interactions of a target of interest with vast numbers of molecules. DECLs hence provide abundant…”
Get full text

SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA by Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D, Halverson, Brayden J, Antelope, Orlando, Mason, Clinton C, Ahmann, Jonathan M, Senina, Anna V, Vellore, Nadeem A, Jones, Courtney L, Zabriskie, Matthew S, Than, Hein, Xiao, Michael J, van Scoyk, Alexandria, Patel, Ami B, Clair, Phillip M, Heaton, William L, Owen, Shawn C, Andersen, Joshua L, Egbert, Christina M, Reisz, Julie A, D'Alessandro, Angelo, Cox, James E, Gantz, Kevin C, Redwine, Hannah M, Iyer, Siddharth M, Khorashad, Jamshid S, Rajabi, Nima, Olsen, Christian A, O'Hare, Thomas, Deininger, Michael W

“…We discovered that the survival and growth of many primary acute myeloid leukemia (AML) samples and cell lines, but not normal CD34+ cells, are dependent on…”
Get full text

Nuclear-Cytoplasmic Transport Is a Therapeutic Target in Myelofibrosis by Yan, Dongqing, Pomicter, Anthony D, Tantravahi, Srinivas, Mason, Clinton C, Senina, Anna V, Ahmann, Jonathan M, Wang, Qiang, Than, Hein, Patel, Ami B, Heaton, William L, Eiring, Anna M, Clair, Phillip M, Gantz, Kevin C, Redwine, Hannah M, Swierczek, Sabina I, Halverson, Brayden J, Baloglu, Erkan, Shacham, Sharon, Khorashad, Jamshid S, Kelley, Todd W, Salama, Mohamed E, Miles, Rodney R, Boucher, Kenneth M, Prchal, Josef T, O'Hare, Thomas, Deininger, Michael W

“…Myelofibrosis is a hematopoietic stem cell neoplasm characterized by bone marrow reticulin fibrosis, extramedullary hematopoiesis, and frequent transformation…”
Get full text

Abstract LB109: A critical role for SIRT5 in acute myeloid leukemia metabolism by Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D., Halverson, Brayden J., Antelope, Orlando, Mason, Clinton C., Ahmann, Jonathan M., Senina, Anna V., Jones, Courtney L. L., Zabriskie, Matthew S., Than, Hein, Xiao, Michael J., van Scoyk, Alexandria, Patel, Ami B., Heaton, William L. L., Owen, Shawn C., Andersen, Joshua L., Egbert, Christina M., Reisz, Julie A., D'Alessandro, Angelo, Cox, James E., Gantz, Kevin C., Redwine, Hannah M., Iyer, Siddharth M., Khorashad, Jamshid S., Rajabi, Nima, Olsen, Christian A., O'Hare, Thomas, Deininger, Michael W.

“…Standard of care for AML includes chemotherapy and stem cell transplant, with 5-year survival rates <30%. We sought to identify genes critical to AML cells,…”
Get full text