Search Results - "Halstead, Miriam F"

The Myosin C-Loop Is an Allosteric Actin Contact Sensor in Actomyosin by Ajtai, Katalin, Halstead, Miriam F, Nyitrai, Miklós, Penheiter, Alan R, Zheng, Ye, Burghardt, Thomas P

“…Actin and myosin form the molecular motor in muscle. Myosin is the enzyme performing ATP hydrolysis under the allosteric control of actin such that actin…”
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In Situ Fluorescent Protein Imaging with Metal Film-Enhanced Total Internal Reflection Microscopy by Burghardt, Thomas P., Charlesworth, Jon E., Halstead, Miriam F., Tarara, James E., Ajtai, Katalin

“…Fluorescence detection of single molecules provides a means to investigate protein dynamics minus ambiguities introduced by ensemble averages of unsynchronized…”
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GFP-Tagged Regulatory Light Chain Monitors Single Myosin Lever-Arm Orientation in a Muscle Fiber by Burghardt, Thomas P., Ajtai, Katalin, Chan, Daniel K., Halstead, Miriam F., Li, Jinhui, Zheng, Ye

“…Myosin is the molecular motor in muscle-binding actin and executing a power stroke by rotating its lever arm through an angle of ∼70° to translate actin…”
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An Unusual Transduction Pathway in Human Tonic Smooth Muscle Myosin by Halstead, Miriam F., Ajtai, Katalin, Penheiter, Alan R., Spencer, Joshua D., Zheng, Ye, Morrison, Emma A., Burghardt, Thomas P.

“…The motor protein myosin binds actin and ATP, producing work by causing relative translation of the proteins while transducing ATP free energy. Smooth muscle…”
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