Search Results - "Halstead, Anna"
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Emergence of immune-related adverse events correlates with pathological complete response in patients receiving pembrolizumab for early triple-negative breast cancer
Published in Oncoimmunology (31-12-2023)“…Based upon results of the KEYNOTE-522 trial and following approval by regulatory authorities, the addition of pembrolizumab to chemotherapy is now the…”
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Real world, multicentre patterns of treatment and survival in metastatic renal cell carcinoma with the UK Renal Oncology Collaborative (UK ROC): Is it time to look favourably on first‐line immunotherapy containing combinations in all IMDC groups?
Published in Cancer medicine (Malden, MA) (01-06-2024)“…Introduction Clinical trials show improved progression‐free survival (PFS) and overall survival (OS) in first‐line metastatic renal cell carcinoma (mRCC)…”
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How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development
Published in Micromachines (Basel) (10-03-2020)“…Bringing a diagnostic point of care test (POCT) to a healthcare market can be a painful experience as it requires the manufacturer to meet considerable…”
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COVID-19 rapid diagnostics: practice review
Published in Emergency medicine journal : EMJ (01-01-2022)“…Point-of-care tests for SARS-CoV-2 could enable rapid rule-in and/or rule-out of COVID-19, allowing rapid and accurate patient cohorting and potentially…”
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A high-resolution melt curve toolkit to identify lineage-defining SARS-CoV-2 mutations
Published in Scientific reports (08-03-2023)“…The emergence of severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern (VOCs), with mutations linked to increased transmissibility, vaccine…”
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Optimization of SARS-CoV-2 culture from clinical samples for clinical trial applications
Published in mSphere (16-10-2024)“…Clinical trials of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapeutics often include virological secondary endpoints to compare viral…”
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Examining the effect of evaluation sample size on the sensitivity and specificity of COVID-19 diagnostic tests in practice: a simulation study
Published in Diagnostic and prognostic research (25-04-2022)“…In response to the global COVID-19 pandemic, many in vitro diagnostic (IVD) tests for SARS-CoV-2 have been developed. Given the urgent clinical demand,…”
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Multicenter Diagnostic Evaluation of OnSite COVID-19 Rapid Test (CTK Biotech) among Symptomatic Individuals in Brazil and the United Kingdom
Published in Microbiology spectrum (15-06-2023)“…The COVID-19 pandemic has given rise to numerous commercially available antigen rapid diagnostic tests (Ag-RDTs). To generate and to share accurate and…”
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Strategies to implement SARS-CoV-2 point-of-care testing into primary care settings: a qualitative secondary analysis guided by the Behaviour Change Wheel
Published in Implementation science communications (18-12-2021)“…The purpose of this study is to develop a theory-driven understanding of the barriers and facilitators underpinning physicians' attitudes and capabilities to…”
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