Search Results - "Halpert, M. M."
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CD8 + CD161 + T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential
Published in Frontiers in immunology (01-02-2021)“…NK1.1 and its human homolog CD161 are expressed on NK cells, subsets of CD4 and CD8 T cells, and NKT cells. While the expression of NK1.1 is thought to be…”
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Dendritic cell vaccination plus low-dose doxorubicin for the treatment of spontaneous canine hemangiosarcoma
Published in Cancer gene therapy (01-09-2019)“…Angiosarcoma is a deadly neoplasm of the vascular endothelium. Metastatic disease is often present at diagnosis, and 5-year survival is only 10–35%. Although…”
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MHC class I and II peptide homology regulates the cellular immune response
Published in The FASEB journal (01-06-2020)“…Mammalian immune responses are initiated by “danger” signals––immutable molecular structures known as PAMPs. When detected by fixed, germline encoded…”
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Evaluations for in vitro correlates of immunogenicity of inactivated influenza a H5, H7 and H9 vaccines in humans
Published in PloS one (11-12-2012)“…Serum antibody responses in humans to inactivated influenza A (H5N1), (H9N2) and A (H7) vaccines have been varied but frequently low, particularly for subunit…”
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AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity
Published in Frontiers in immunology (15-01-2018)“…Dendritic cells (DCs) must integrate a broad array of environmental cues to exact control over downstream immune responses including T H polarization. The…”
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Stepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity
Published in International reviews of immunology (03-09-2015)“…As a structural component of the multi-aminoacyl tRNA synthetase (mARS) complex, AIMp1, also known as p43, hasn't until recently been recognized for its…”
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TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling
Published in The Journal of immunology (1950) (01-09-2011)“…Receptors encoded within the Trem locus have been shown to play an important role in modulating the cellular response to pattern recognition receptor…”
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A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain
Published in Pain (Amsterdam) (01-09-2020)“…Over the last 2 decades, affirmative diagnoses of osteoarthritis (OA) in the United States have tripled due to increasing rates of obesity and an aging…”
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Paediatric vs adult retinal detachment
Published in Eye (London) (01-12-2007)“…To evaluate the causes, incidences, characteristics, and treatment outcomes of paediatric vs adult retinal detachment. One hundred and sixty (136 patients) out…”
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Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC
Published in PloS one (19-12-2012)“…Though remissions have been observed following allo-HSCT for the treatment of CLL, many CLL patients are ineligible for transplant due to the lack of…”
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Precipitation Patterns Associated with the High Index Phase of the Southern Oscillation
Published in Journal of climate (01-03-1989)“…The relationships are examined between precipitation and the high index phase of the Southern Oscillation (SO) for 19 regions of the globe which have…”
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Multifactoral immune modulation potentiates durable remission in multiple models of aggressive malignancy
Published in The FASEB journal (31-05-2024)“…Tumors typically lack canonical danger signals required to activate adaptive immunity and also frequently employ substantial immunomodulatory mechanisms that…”
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A subset of cytotoxic effector memory T cells enhances CAR T cell efficacy in a model of pancreatic ductal adenocarcinoma
Published in Science translational medicine (05-05-2021)“…In humans, the natural killer (NK) cell marker CD161 identifies several subsets of T cells, including a polyclonal CD8 αβ T cell receptor-expressing subset…”
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Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7
Published in Stem cells and development (15-05-2016)“…The remarkable functional plasticity of professional antigen-presenting cells (APCs) allows the adaptive immune system to respond specifically to an incredibly…”
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Quantifying Southern Oscillation–Precipitation Relationships
Published in Journal of climate (01-05-1996)“…A series of earlier studies has identified regions of the world in which precipitation appears to have a consistent relationship with the Southern Oscillation…”
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Surgery of the hereditary subluxated lens in children
Published in Ophthalmology (Rochester, Minn.) (01-04-1996)“…To describe the criteria and techniques for the surgery of hereditary subluxated lens in children and analyze the visual and surgical outcome after an extended…”
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Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy
Published in Infection and immunity (01-09-2017)“…Chagas disease, caused by infection with the protozoan parasite , is a leading cause of heart disease ("chagasic cardiomyopathy") in Latin America,…”
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Modeling Dendritic Cell Vaccination for Influenza Prophylaxis: Potential Applications for Niche Populations
Published in The Journal of infectious diseases (01-06-2013)“…Background. Cancer patients can exhibit negligible responses to prophylactic vaccinations, including influenza vaccination. To help address this issue, we…”
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Surface Temperature Patterns Associated with the Southern Oscillation
Published in Journal of climate (01-06-1992)“…The "typical" global and large-scale regional temperature patterns associated with the low (warm) and high (cold) phases of the Southern Oscillation (SO) are…”
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CLIMATE ASSESSMENT FOR 2001
Published in Bulletin of the American Meteorological Society (01-06-2002)“…Global temperatures in 2001 were 0.51°C (0.92°F) above the long-term (1880–2000) average, which places 2001 as the second warmest year in the 122-year…”
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