Search Results - "Halpern, Anita"

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse[S] by Quinet, Elaine M., Basso, Michael D., Halpern, Anita R., Yates, David W., Steffan, Robert J., Clerin, Valerie, Resmini, Christine, Keith, James C., Berrodin, Thomas J., Feingold, Irene, Zhong, Wenyan, Hartman, Helen B., Evans, Mark J., Gardell, Stephen J., DiBlasio-Smith, Elizabeth, Mounts, William M., LaVallie, Edward R., Wrobel, Jay, Nambi, Ponnal, Vlasuk, George P.

“…Liver X receptors (LXRs) are ligand-activated transcription factors that coordinate regulation of gene expression involved in several cellular functions but…”
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Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor by Quinet, Elaine M., Savio, Dawn A., Halpern, Anita R., Chen, Liang, Miller, Christopher P., Nambi, Ponnal

“…Liver X receptors (LXRs) play key roles in the regulation of cholesterol homeostasis by limiting cholesterol accumulation in macrophages within arterial wall…”
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Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells by DiBlasio-Smith, Elizabeth A, Arai, Maya, Quinet, Elaine M, Evans, Mark J, Kornaga, Tad, Basso, Michael D, Chen, Liang, Feingold, Irene, Halpern, Anita R, Liu, Qiang-Yuan, Nambi, Ponnal, Savio, Dawn, Wang, Shuguang, Mounts, William M, Isler, Jennifer A, Slager, Anna M, Burczynski, Michael E, Dorner, Andrew J, LaVallie, Edward R

“…LXRs (Liver X Receptor alpha and beta) are nuclear receptors that act as ligand-activated transcription factors. LXR activation causes upregulation of genes…”
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Discovery of Phenyl Acetic Acid Substituted Quinolines as Novel Liver X Receptor Agonists for the Treatment of Atherosclerosis by Hu, Baihua, Collini, Michael, Unwalla, Rayomand, Miller, Christopher, Singhaus, Robert, Quinet, Elaine, Savio, Dawn, Halpern, Anita, Basso, Michael, Keith, James, Clerin, Valerie, Chen, Liang, Resmini, Christine, Liu, Qiang-Yuan, Feingold, Irene, Huselton, Christine, Azam, Farooq, Farnegardh, Mathias, Enroth, Cristofer, Bonn, Tomas, Goos-Nilsson, Annika, Wilhelmsson, Anna, Nambi, Ponnal, Wrobel, Jay

“…A structure-based approach was used to optimize our new class of quinoline LXR modulators leading to phenyl acetic acid substituted quinolines 15 and 16. Both…”
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Carboxylic acid based quinolines as liver X receptor modulators that have LXRβ receptor binding selectivity by Hu, Baihua, Quinet, Elaine, Unwalla, Rayomand, Collini, Mike, Jetter, James, Dooley, Rebecca, Andraka, Diane, Nogle, Lisa, Savio, Dawn, Halpern, Anita, Goos-Nilsson, Annika, Wilhelmsson, Anna, Nambi, Ponnal, Wrobel, Jay

“…A series of potent and binding selective LXRβ agonists was developed using the previously reported non-selective LXR ligand WAY-254011 as a structural…”
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Abstract 3718: MMP-12 Inhibitor Reduces Severity of ANGII-induced Aortic Abdominal Aneurysms in apoE−/− Mice by Savio, Dawn A, Halpern, Anita R, Wu, Yuchuan, Li, Wei, Sypek, Joseph, Quinet, Elaine M

“…Abstract only Abdominal aortic aneurysm (AAA) is an inflammatory disorder characterized by local connective tissue degradation, macrophage recruitment and…”
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Further modification on phenyl acetic acid based quinolines as liver X receptor modulators by Hu, Baihua, Jetter, James, Kaufman, David, Singhaus, Robert, Bernotas, Ronald, Unwalla, Rayomand, Quinet, Elaine, Savio, Dawn, Halpern, Anita, Basso, Michael, Keith, James, Clerin, Valerie, Chen, Liang, Liu, Qiang-Yuan, Feingold, Irene, Huselton, Christine, Azam, Farooq, Goos-Nilsson, Annika, Wilhelmsson, Anna, Nambi, Ponnal, Wrobel, Jay

“…A series of phenyl acetic acid based quinolines was prepared as LXR modulators. An SAR study in which the C-3 and C-8 positions of the quinoline core were…”
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Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting by Quinet, Elaine M, Savio, Dawn A, Halpern, Anita R, Chen, Liang, Schuster, Gertrude U, Gustafsson, Jan-Ake, Basso, Mike D, Nambi, Ponnal

“…The nuclear receptors liver X receptor (LXR) LXRalpha and LXRbeta are differentially expressed ligand-activated transcription factors that induce genes…”
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Prescribed fire and tanoak (Notholithocarpus densiflorus ) associated cultural plant resources of the Karuk and Yurok Peoples of California by Halpern, Arielle Anita

“…The targeted application of prescribed fire has long been used by Native Californian peoples to manage plant resources of cultural value. Their ability to…”
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Carboxylic acid based quinolines as liver X receptor modulators that have LXRbeta receptor binding selectivity by Hu, Baihua, Quinet, Elaine, Unwalla, Rayomand, Collini, Mike, Jetter, James, Dooley, Rebecca, Andraka, Diane, Nogle, Lisa, Savio, Dawn, Halpern, Anita, Goos-Nilsson, Annika, Wilhelmsson, Anna, Nambi, Ponnal, Wrobel, Jay

“…A series of potent and binding selective LXRbeta agonists was developed using the previously reported non-selective LXR ligand WAY-254011 as a structural…”
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DIFFERENTIAL DECISION STRATEGY BETWEEN SCHIZOPHRENIA AND MANIA WITHIN THE CONTEXT OF A RECOGNITION MEMORY TASK by HALPERN, ANITA

“…Established convention has held that schizophrenia and mania are distinct clinical entities. Yet, the matter of differential diagnosis remains problematic…”
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The effects of level of depression and instruction on decision strategy in recognition memory by Halpern, Anita

“…The present study used Signal Detection Theory (SDT) to examine the performance of depressed as compared with normal subjects on a task of Recognition Memory…”
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The determination of barbiturates in blood and urine by gas-liquid chromatography with a peak shift for qualitative confirmation by Parker, K D, Wright, J A, Halpern, A F, Hine, C H

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