Search Results - "Hallström, Björn M."

Altered sterol composition renders yeast thermotolerant by Caspeta, Luis, Chen, Yun, Ghiaci, Payam, Feizi, Amir, Buskov, Steen, Hallström, Björn M., Petranovic, Dina, Nielsen, Jens

“…Ethanol production for use as a biofuel is mainly achieved through simultaneous saccharification and fermentation by yeast. Operating at ≥40°C would be…”
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Gene‐specific correlation of RNA and protein levels in human cells and tissues by Edfors, Fredrik, Danielsson, Frida, Hallström, Björn M, Käll, Lukas, Lundberg, Emma, Pontén, Fredrik, Forsström, Björn, Uhlén, Mathias

“…An important issue for molecular biology is to establish whether transcript levels of a given gene can be used as proxies for the corresponding protein levels…”
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Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast by Huang, Mingtao, Bai, Yunpeng, Sjostrom, Staffan L., Hallström, Björn M., Liu, Zihe, Petranovic, Dina, Uhlén, Mathias, Joensson, Haakan N., Andersson-Svahn, Helene, Nielsen, Jens

“…There is an increasing demand for biotech-based production of recombinant proteins for use as pharmaceuticals in the food and feed industry and in industrial…”
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Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance by Lee, Sunjae, Zhang, Cheng, Kilicarslan, Murat, Piening, Brian D., Bjornson, Elias, Hallström, Björn M., Groen, Albert K., Ferrannini, Ele, Laakso, Markku, Snyder, Michael, Blüher, Matthias, Uhlen, Mathias, Nielsen, Jens, Smith, Ulf, Serlie, Mireille J., Boren, Jan, Mardinoglu, Adil

“…To investigate the biological processes that are altered in obese subjects, we generated cell-specific integrated networks (INs) by merging genome-scale…”
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Efficient protein production by yeast requires global tuning of metabolism by Huang, Mingtao, Bao, Jichen, Hallström, Björn M., Petranovic, Dina, Nielsen, Jens

“…The biotech industry relies on cell factories for production of pharmaceutical proteins, of which several are among the top-selling medicines. There is,…”
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Transcriptomics resources of human tissues and organs by Uhlén, Mathias, Hallström, Björn M, Lindskog, Cecilia, Mardinoglu, Adil, Pontén, Fredrik, Nielsen, Jens

“…Quantifying the differential expression of genes in various human organs, tissues, and cell types is vital to understand human physiology and disease…”
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Quantification and discovery of sequence determinants of protein‐per‐mRNA amount in 29 human tissues by Eraslan, Basak, Wang, Dongxue, Gusic, Mirjana, Prokisch, Holger, Hallström, Björn M, Uhlén, Mathias, Asplund, Anna, Pontén, Frederik, Wieland, Thomas, Hopf, Thomas, Hahne, Hannes, Kuster, Bernhard, Gagneur, Julien

“…Despite their importance in determining protein abundance, a comprehensive catalogue of sequence features controlling protein‐to‐mRNA (PTR) ratios and a…”
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Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium by Yu, Nancy Yiu-Lin, Hallström, Björn M, Fagerberg, Linn, Ponten, Fredrik, Kawaji, Hideya, Carninci, Piero, Forrest, Alistair R R, Hayashizaki, Yoshihide, Uhlén, Mathias, Daub, Carsten O

“…Understanding the normal state of human tissue transcriptome profiles is essential for recognizing tissue disease states and identifying disease markers…”
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The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling by Habuka, Masato, Fagerberg, Linn, Hallström, Björn M, Pontén, Fredrik, Yamamoto, Tadashi, Uhlen, Mathias

“…To understand functions and diseases of urinary bladder, it is important to define its molecular constituents and their roles in urinary bladder biology. Here,…”
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Mammalian evolution may not be strictly bifurcating by Hallström, Björn M, Janke, Axel

“…The massive amount of genomic sequence data that is now available for analyzing evolutionary relationships among 31 placental mammals reduces the stochastic…”
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Expression of Human Skin-Specific Genes Defined by Transcriptomics and Antibody-Based Profiling by Edqvist, Per-Henrik D., Fagerberg, Linn, Hallström, Björn M., Danielsson, Angelika, Edlund, Karolina, Uhlén, Mathias, Pontén, Fredrik

“…To increase our understanding of skin, it is important to define the molecular constituents of the cell types and epidermal layers that signify normal skin. We…”
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AS3MT-mediated tolerance to arsenic evolved by multiple independent horizontal gene transfers from bacteria to eukaryotes by Palmgren, Michael, Engström, Karin, Hallström, Björn M, Wahlberg, Karin, Søndergaard, Dan Ariel, Säll, Torbjörn, Vahter, Marie, Broberg, Karin

“…Organisms have evolved the ability to tolerate toxic substances in their environments, often by producing metabolic enzymes that efficiently detoxify the…”
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The human liver‐specific proteome defined by transcriptomics and antibody‐based profiling by Kampf, Caroline, Mardinoglu, Adil, Fagerberg, Linn, Hallström, Björn M., Edlund, Karolina, Lundberg, Emma, Pontén, Fredrik, Nielsen, Jens, Uhlen, Mathias

“…ABSTRACT Human liver physiology and the genetic etiology of the liver diseases can potentially be elucidated through the identification of proteins with…”
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The kidney transcriptome and proteome defined by transcriptomics and antibody-based profiling by Habuka, Masato, Fagerberg, Linn, Hallström, Björn M, Kampf, Caroline, Edlund, Karolina, Sivertsson, Åsa, Yamamoto, Tadashi, Pontén, Fredrik, Uhlén, Mathias, Odeberg, Jacob

“…To understand renal functions and disease, it is important to define the molecular constituents of the various compartments of the kidney. Here, we used…”
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Defining the Human Adipose Tissue Proteome To Reveal Metabolic Alterations in Obesity by Mardinoglu, Adil, Kampf, Caroline, Asplund, Anna, Fagerberg, Linn, Hallström, Björn M, Edlund, Karolina, Blüher, Matthias, Pontén, Fredrik, Uhlen, Mathias, Nielsen, Jens

“…White adipose tissue (WAT) has a major role in the progression of obesity. Here, we combined data from RNA-Seq and antibody-based immunohistochemistry to…”
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Evolution of P2A and P5A ATPases: ancient gene duplications and the red algal connection to green plants revisited by Palmgren, Michael, Sørensen, Danny Mollerup, Hallström, Björn M., Säll, Torbjörn, Broberg, Karin

“…In a search for slowly evolving nuclear genes that may cast light on the deep evolution of plants, we carried out phylogenetic analyses of two…”
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Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex by Sjöstedt, Evelina, Fagerberg, Linn, Hallström, Björn M, Häggmark, Anna, Mitsios, Nicholas, Nilsson, Peter, Pontén, Fredrik, Hökfelt, Tomas, Uhlén, Mathias, Mulder, Jan

“…The mammalian brain is a complex organ composed of many specialized cells, harboring sets of both common, widely distributed, as well as specialized and…”
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The human pancreas proteome defined by transcriptomics and antibody-based profiling by Danielsson, Angelika, Pontén, Fredrik, Fagerberg, Linn, Hallström, Björn M, Schwenk, Jochen M, Uhlén, Mathias, Korsgren, Olle, Lindskog, Cecilia

“…The pancreas is composed of both exocrine glands and intermingled endocrine cells to execute its diverse functions, including enzyme production for digestion…”
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Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer by O'Hurley, Gillian, Busch, Christer, Fagerberg, Linn, Hallström, Björn M, Stadler, Charlotte, Tolf, Anna, Lundberg, Emma, Schwenk, Jochen M, Jirström, Karin, Bjartell, Anders, Gallagher, William M, Uhlén, Mathias, Pontén, Fredrik

“…To better understand prostate function and disease, it is important to define and explore the molecular constituents that signify the prostate gland. The aim…”
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Coalescent-based genome analyses resolve the early branches of the euarchontoglires by Kumar, Vikas, Hallström, Björn M, Janke, Axel

“…Despite numerous large-scale phylogenomic studies, certain parts of the mammalian tree are extraordinarily difficult to resolve. We used the coding regions…”
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