Search Results - "Hallin, Johan"
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Contrasting evolutionary genome dynamics between domesticated and wild yeasts
Published in Nature genetics (01-06-2017)“…Jia-Xing Yue, Gianni Liti and colleagues use long-read sequencing to generate complete genome assemblies of 7 Saccharomyces cerevisiae and 5 Saccharomyces…”
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2
Regulation plays a multifaceted role in the retention of gene duplicates
Published in PLoS biology (22-11-2019)“…A gene duplication can lead to all sorts of problems in a cell. However, it can also lead to all sorts of benefits. Beneficial or not, the gene duplicates…”
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Predicting quantitative traits from genome and phenome with near perfect accuracy
Published in Nature communications (10-05-2016)“…In spite of decades of linkage and association studies and its potential impact on human health, reliable prediction of an individual’s risk for heritable…”
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4
Genetically controlled mtDNA deletions prevent ROS damage by arresting oxidative phosphorylation
Published in eLife (08-07-2022)“…Deletion of mitochondrial DNA in eukaryotes is currently attributed to rare accidental events associated with mitochondrial replication or repair of…”
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5
Clonal Heterogeneity Influences the Fate of New Adaptive Mutations
Published in Cell reports (Cambridge) (17-10-2017)“…The joint contribution of pre-existing and de novo genetic variation to clonal adaptation is poorly understood but essential to designing successful…”
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Powerful decomposition of complex traits in a diploid model
Published in Nature communications (02-11-2016)“…Explaining trait differences between individuals is a core and challenging aim of life sciences. Here, we introduce a powerful framework for complete…”
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7
Scan-o-matic: High-Resolution Microbial Phenomics at a Massive Scale
Published in G3 : genes - genomes - genetics (01-09-2016)“…The capacity to map traits over large cohorts of individuals-phenomics-lags far behind the explosive development in genomics. For microbes, the estimation of…”
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Testing the Genomic Shock Hypothesis Using Transposable Element Expression in Yeast Hybrids
Published in Frontiers in fungal biology (23-08-2021)“…Transposable element (TE) insertions are a source of structural variation and can cause genetic instability and gene expression changes. A host can limit the…”
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Similarities in biological processes can be used to bridge ecology and molecular biology
Published in Evolutionary applications (01-07-2020)“…Much of the research in biology aims to understand the origin of diversity. Naturally, ecological diversity was the first object of study, but we now have the…”
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Turnover of ribosome-associated transcripts from de novo ORFs produces gene-like characteristics available for de novo gene emergence in wild yeast populations
Published in Genome research (01-06-2019)“…Little is known about the rate of emergence of de novo genes, what their initial properties are, and how they spread in populations. We examined wild yeast…”
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Intragenic repeat expansion in the cell wall protein gene HPF1 controls yeast chronological aging
Published in Genome research (01-05-2020)“…Aging varies among individuals due to both genetics and environment, but the underlying molecular mechanisms remain largely unknown. Using a highly recombined…”
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A single-nucleotide change underlies the genetic assimilation of a plastic trait
Published in Science advances (03-02-2021)“…Genetic assimilation-the evolutionary process by which an environmentally induced phenotype is made constitutive-represents a fundamental concept in…”
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