Search Results - "Halligan, Edythe M."

Frequent amyloid deposition without significant cognitive impairment among the elderly by Aizenstein, Howard Jay, Nebes, Robert D, Saxton, Judith A, Price, Julie C, Mathis, Chester A, Tsopelas, Nicholas D, Ziolko, Scott K, James, Jeffrey A, Snitz, Beth E, Houck, Patricia R, Bi, Wenzhu, Cohen, Ann D, Lopresti, Brian J, DeKosky, Steven T, Halligan, Edythe M, Klunk, William E

“…To characterize the prevalence of amyloid deposition in a clinically unimpaired elderly population, as assessed by Pittsburgh Compound B (PiB) positron…”
Get more information

Cognitive Slowing Associated With Elevated Serum Anticholinergic Activity in Older Individuals is Decreased by Caffeine Use by Nebes, Robert D., Ph.D, Pollock, Bruce G., M.D., Ph.D, Halligan, Edythe M., M.A, Houck, Patricia, M.S, Saxton, Judith A., Ph.D

“…Objectives This study examined whether some of the age-associated decrements in basic cognitive resources (information-processing speed and working memory)…”
Get full text

Self-Reported Sleep Quality Predicts Poor Cognitive Performance in Healthy Older Adults by Nebes, Robert D., Buysse, Daniel J., Halligan, Edythe M., Houck, Patricia R., Monk, Timothy H.

“…This study examined the relation between sleep quality and cognitive performance in older adults, controlling for common medical comorbidities. Participants…”
Get full text

The greater sensitivity of elderly APOE ε4 carriers to anticholinergic medications is independent of cerebrovascular disease risk by Nebes, Robert D, Pollock, Bruce G, Perera, Subashan, Halligan, Edythe M, Saxton, Judith A

“…Recent studies found use of anticholinergic medications to be associated with greater performance decrements in older persons who carry an ε4 allele of the…”
Get more information

The Relation of White Matter Hyperintensities to Cognitive Performance in the Normal Old: Education Matters by Nebes, Robert D., Meltzer, Carolyn C., Whyte, Ellen M., Scanlon, Joelle M., Halligan, Edythe M., Saxton, Judith A., Houck, Patricia R., Boada, Fernando E., DeKosky, Steven T.

“…This study examined whether the severity of cerebral white matter abnormalities (evident on MR images as white matter hyperintensities (WMH)) was related to…”
Get full text

Cognitive aging in persons with minimal amyloid-β and white matter hyperintensities by Nebes, Robert D., Snitz, Beth E., Cohen, Ann D., Aizenstein, Howard J., Saxton, Judith A., Halligan, Edythe M., Mathis, Chester A., Price, Julie C., Kamboh, M.Ilyas, Weissfeld, Lisa A., Klunk, William E.

“…Substantial individual differences exist in the magnitude of the cognitive decline associated with normal aging. Potential contributors to this intersubject…”
Get full text

Serum Anticholinergic Activity and Motor Performance in Elderly Persons by Nebes, Robert D., Pollock, Bruce G., Halligan, Edythe M., Kirshner, Margaret A., Houck, Patricia R.

“…Background. Medications prescribed to elderly persons often have an anticholinergic effect, as do many commonly used over-the-counter drugs. Anticholinergic…”
Get full text

Intra-individual variability in gait and in cognitive performance are not related in the elderly by Sukits, Alison L., Nebes, Robert D., Chambers, April J., Ledgerwood, Aaron, Halligan, Edythe M., Perera, Subashan, Cham, Rakié

“…As humans age, the amount of intra-individual variability (IIV) present in both their gait and their cognitive performance tends to increase. Both gait and…”
Get full text

Longitudinal increase in the volume of white matter hyperintensities in late-onset depression by Nebes, Robert D., Reynolds III, Charles F., Boada, Fernando, Meltzer, Carolyn C., Fukui, Melanie B., Saxton, Judith, Halligan, Edythe M., DeKosky, Steven T.

“…Background Cerebrovascular disease is thought to play a role in the pathogenesis of geriatric major depression. One finding supporting such a ‘vascular…”
Get full text

IC-P2-110: Classification of amyloid-positivity in cognitively normal elderly controls: Comparison of objective approaches with visual reads by Klunk, William E, Cohen, Ann D, Price, Julie C, Mathis, Chester A, Wolk, David A, Mountz, James M, Weissfeld, Lisa A, Ziolko, Scott K, Nebes, Robert D, Aizenstein, Howard J, Saxton, Judith A, Snitz, Beth E, Houck, Patty R, Halligan, Edythe M, DeKosky, Steven T

Get full text

Instantiation of semantic categories in sentence comprehension by Alzheimer patients by Nebes, R D, Halligan, E M

“…This study examined whether Alzheimer patients can make elaborative inferences based on the semantic context provided by a sentence. More specifically, if…”
Get more information

Sentence Context Influences the Interpretation of Word Meaning by Alzheimer Patients by Nebes, Robert D., Halligan, Edythe M.

“…This study examined whether, in Alzheimer patients, verbal context selectively activates elements of a word's meaning that are relevant to the context…”
Get full text

Contextual Constraint Facilitates Semantic Decisions About Object Pictures by Alzheimer Patients by Nebes, Robert D, Halligan, Edythe M

“…Semantic constraints produced by sentence context reduce the time normal adults take to decide whether a given stimulus constitutes a meaningful ending to that…”
Get full text

Alzheimer's Disease Does Not Selectively Impair Decisions About Word Meaning by Nebes, Robert D, Halligan, Edythe M

“…Patients with probable Alzheimer's disease (AD) and normal young and older participants were asked to make decisions about the orthography, phonology and…”
Get full text

Cognitive and motor slowing in Alzheimer's disease and geriatric depression by Nebes, R D, Halligan, E M, Rosen, J, Reynolds, 3rd, C F

“…While response slowing on psychological tasks is a symptom of both depression and Alzheimer's disease (AD), the underlying mechanisms may be quite different: a…”
Get more information

Memory Impairment in Elderly Individuals With a Mildly Elevated Serum TSH: The Role of Processing Resources, Depression and Cerebrovascular Disease by Cook, Sarah E., Nebes, Robert D., Halligan, Edythe M., Burmeister, Lynn A., Saxton, Judith A., Ganguli, Mary, Fukui, Melanie B., Meltzer, Carolyn C., Williams, Robert L., DeKosky, Steven T.

“…This study examined whether a mild elevation in serum Thyroid Stimulating Hormone (TSH) in normal older individuals was associated with a cognitive impairment…”
Get full text