Search Results - "Halley, Pamela A"
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Loss of FGF-dependent mesoderm identity and rise of endogenous retinoid signalling determine cessation of body axis elongation
Published in PLoS biology (01-10-2012)“…The endogenous mechanism that determines vertebrate body length is unknown but must involve loss of chordo-neural-hinge (CNH)/axial stem cells and mesoderm…”
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2
Human spinal cord in vitro differentiation pace is initially maintained in heterologous embryonic environments
Published in eLife (21-02-2022)“…Species-specific differentiation pace in vitro indicates that some aspects of neural differentiation are governed by cell intrinsic properties. Here we…”
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3
Wnt regulates amino acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos
Published in EMBO reports (07-01-2020)“…Amino acids are essential for cellular metabolism, and it is important to understand how nutrient supply is coordinated with changing energy requirements…”
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4
FGF signalling regulates chromatin organisation during neural differentiation via mechanisms that can be uncoupled from transcription
Published in PLoS genetics (01-07-2013)“…Changes in higher order chromatin organisation have been linked to transcriptional regulation; however, little is known about how such organisation alters…”
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5
A lateral protrusion latticework connects neuroepithelial cells and is regulated during neurogenesis
Published in Journal of cell science (15-03-2022)“…Dynamic contacts between cells within the developing neuroepithelium are poorly understood but play important roles in cell and tissue morphology and cell…”
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Correction: FGF Signalling Regulates Chromatin Organisation during Neural Differentiation via Mechanisms that Can Be Uncoupled from Transcription
Published in PLoS genetics (01-08-2013)“…[This corrects the article DOI: 10.1371/journal.pgen.1003614.]…”
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Lineage tracing axial progenitors using Nkx1-2CreERT2 mice defines their trunk and tail contributions
Published in Development (Cambridge) (02-10-2018)“…The vertebrate body forms by continuous generation of new tissue from progenitors at the posterior end of the embryo. The study of these axial progenitors has…”
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8
Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo
Published in Development (Cambridge) (01-08-2014)“…Here, we exploit the spatial separation of temporal events of neural differentiation in the elongating chick body axis to provide the first analysis of…”
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Lineage tracing of axial progenitors using Nkx1-2CreER T2 mice defines their trunk and tail contributions
Published in Development (Cambridge) (02-10-2018)“…The vertebrate body forms by continuous generation of new tissue from progenitors at the posterior end of the embryo. The study of these axial progenitors has…”
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Journal Article -
10
FGF Signalling Regulates Chromatin Organisation during Neural Differentiation via Mechanisms that Can Be Uncoupled from Transcription: e1003614
Published in PLoS genetics (01-07-2013)“…Changes in higher order chromatin organisation have been linked to transcriptional regulation; however, little is known about how such organisation alters…”
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Journal Article