Search Results - "Hallett, Timothy B"

Scaling up prevention and treatment towards the elimination of hepatitis C: a global mathematical model by Heffernan, Alastair, Cooke, Graham S, Nayagam, Shevanthi, Thursz, Mark, Hallett, Timothy B

“…The revolution in hepatitis C virus (HCV) treatment through the development of direct-acting antivirals (DAAs) has generated international interest in the…”
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Future challenges for clinical care of an ageing population infected with HIV: a modelling study by Smit, Mikaela, Dr, Brinkman, Kees, MD, Geerlings, Suzanne, MD, Smit, Colette, PhD, Thyagarajan, Kalyani, PhD, Sighem, Ard van, PhD, de Wolf, Frank, Prof, Hallett, Timothy B, Prof

“…Summary Background The population infected with HIV is getting older and these people will increasingly develop age-related non-communicable diseases (NCDs)…”
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Requirements for global elimination of hepatitis B: a modelling study by Nayagam, Shevanthi, Dr, Thursz, Mark, Prof, Sicuri, Elisa, PhD, Conteh, Lesong, PhD, Wiktor, Stefan, MD, Low-Beer, Daniel, PhD, Hallett, Timothy B, Prof

“…Summary Background Despite the existence of effective prevention and treatment interventions, hepatitis B virus (HBV) infection continues to cause nearly 1…”
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The impact of the timely birth dose vaccine on the global elimination of hepatitis B by de Villiers, Margaret J., Nayagam, Shevanthi, Hallett, Timothy B.

“…In 2016 the World Health Organization set the goal of eliminating hepatitis B globally by 2030. Horizontal transmission has been greatly reduced in most…”
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Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here? by Cohen, Myron S, Prof, Smith, M Kumi, MPH, Muessig, Kathryn E, PhD, Hallett, Timothy B, Prof, Powers, Kimberly A, PhD, Kashuba, Angela D, Prof

“…Summary Antiretroviral drugs that inhibit viral replication were expected to reduce transmission of HIV by lowering the concentration of HIV in the genital…”
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Modeling the epidemiological impact of the UNAIDS 2025 targets to end AIDS as a public health threat by 2030 by Stover, John, Glaubius, Robert, Teng, Yu, Kelly, Sherrie, Brown, Tim, Hallett, Timothy B, Revill, Paul, Bärnighausen, Till, Phillips, Andrew N, Fontaine, Christopher, Frescura, Luisa, Izazola-Licea, Jose Antonio, Semini, Iris, Godfrey-Faussett, Peter, De Lay, Paul R, Benzaken, Adèle Schwartz, Ghys, Peter D

“…UNAIDS has established new program targets for 2025 to achieve the goal of eliminating AIDS as a public health threat by 2030. This study reports on efforts to…”
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Maximising the effect of combination HIV prevention through prioritisation of the people and places in greatest need: a modelling study by Anderson, Sarah-Jane, MSc, Cherutich, Peter, MBChB, Kilonzo, Nduku, PhD, Cremin, Ide, PhD, Fecht, Daniela, PhD, Kimanga, Davies, MSc, Harper, Malayah, MSc (Eco), Masha, Ruth Laibon, MPH, Ngongo, Prince Bahati, MBA, Maina, William, MPH, Dybul, Mark, MD, Hallett, Timothy B, Prof

“…Summary Background Epidemiological data show substantial variation in the risk of HIV infection between communities within African countries. We hypothesised…”
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Mathematical models in the evaluation of health programmes by Garnett, Geoffrey P, Prof, Cousens, Simon, Prof, Hallett, Timothy B, PhD, Steketee, Richard, MD, Walker, Neff, Dr

“…Summary Modelling is valuable in the planning and evaluation of interventions, especially when a controlled trial is ethically or logistically impossible…”
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Epidemiological metrics and benchmarks for a transition in the HIV epidemic by Ghys, Peter D, Williams, Brian G, Over, Mead, Hallett, Timothy B, Godfrey-Faussett, Peter

“…Peter Godfrey-Faussett and colleagues present six epidemiological metrics for tracking progress in reducing the public health threat of HIV…”
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Examining the promise of HIV elimination by 'test and treat' in hyperendemic settings by DODD, Peter J, GARNETT, Geoff P, HALLETT, Timothy B

“…It has been suggested that a new strategy for HIV prevention, 'Universal Test and Treat', whereby everyone is tested for HIV once a year and treated…”
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The long-term impact and value of curative therapy for HIV: a modelling analysis by Guzauskas, Gregory F, Hallett, Timothy B

“…Curative therapies (CTx) to achieve durable remission of HIV disease without the need for antiretroviral therapy (ART) are currently being explored. Our…”
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Why the proportion of transmission during early-stage HIV infection does not predict the long-term impact of treatment on HIV incidence by Eaton, Jeffrey W., Hallett, Timothy B.

“…Significance Antiretroviral treatment (ART), which prevents both morbidity and HIV transmission for persons infected with HIV, is now thought to be central to…”
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The value-based price of transformative gene therapy for sickle cell disease: a modeling analysis by Morgan, George, Back, Emily, Besser, Martin, Hallett, Timothy B., Guzauskas, Gregory F.

“…Sickle cell disease (SCD) is an inherited, progressively debilitating blood disorder. Emerging gene therapies (GTx) may lead to a complete remission, the…”
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Elimination of HIV in South Africa through expanded access to antiretroviral therapy: a model comparison study by Hontelez, Jan A C, Lurie, Mark N, Bärnighausen, Till, Bakker, Roel, Baltussen, Rob, Tanser, Frank, Hallett, Timothy B, Newell, Marie-Louise, de Vlas, Sake J

“…Expanded access to antiretroviral therapy (ART) using universal test and treat (UTT) has been suggested as a strategy to eliminate HIV in South Africa within 7…”
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The potential impact of urine-LAM diagnostics on tuberculosis incidence and mortality: A modelling analysis by Ricks, Saskia, Denkinger, Claudia M, Schumacher, Samuel G, Hallett, Timothy B, Arinaminpathy, Nimalan

“…Lateral flow urine lipoarabinomannan (LAM) tests could offer important new opportunities for the early detection of tuberculosis (TB). The currently licensed…”
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Global reporting of progress towards elimination of hepatitis B and hepatitis C by Cui, Fuqiang, Blach, Sarah, Manzengo Mingiedi, Casimir, Gonzalez, Monica Alonso, Sabry Alaama, Ahmed, Mozalevskis, Antons, Séguy, Nicole, Rewari, Bharat Bhushan, Chan, Po-Lin, Le, Linh-Vi, Doherty, Meg, Luhmann, Niklas, Easterbrook, Philippa, Dirac, Mae, de Martel, Catherine, Nayagam, Shevanthi, Hallett, Timothy B, Vickerman, Peter, Razavi, Homie, Lesi, Olufunmiayo, Low-Beer, Daniel

“…The 69th World Health Assembly endorsed the global health sector strategy on viral hepatitis to eliminate viral hepatitis as a public health threat by 2030…”
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Economic and epidemiological evaluation of interventions to reduce the burden of hepatitis C in Yunnan province, China by Heffernan, Alastair, Ma, Yanling, Nayagam, Shevanthi, Chan, Polin, Chen, Zhongdan, Cooke, Graham S, Guo, Yan, Liu, Chuntao, Thursz, Mark, Zhang, Wanyue, Zhang, Xiaobing, Zhang, Xiujie, Jia, Manhong, Hallett, Timothy B

“…The paradigm shift in hepatitis C virus (HCV) treatment options in the last five years has raised the prospect of eliminating the disease as a global health…”
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Understanding the impact of interruptions to HIV services during the COVID-19 pandemic: A modelling study by Jewell, Britta L., Smith, Jennifer A., Hallett, Timothy B.

“…There is concern that the COVID-19 pandemic could severely disrupt HIV services in sub-Saharan Africa. However, it is difficult to determine priorities for…”
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Projections of non-communicable disease and health care costs among HIV-positive persons in Italy and the U.S.A.: A modelling study by Smit, Mikaela, Cassidy, Rachel, Cozzi-Lepri, Alessandro, Quiros-Roldan, Eugenia, Girardi, Enrico, Mammone, Alessia, Antinori, Andrea, Saracino, Annalisa, Bai, Francesca, Rusconi, Stefano, Magnani, Giacomo, Castelli, Francesco, Hsue, Priscilla, d'Arminio Monforte, Antonella, Hallett, Timothy B

“…Country-specific forecasts of the growing non-communicable disease (NCD) burden in ageing HIV-positive patients will be key to guide future HIV policies. We…”
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Determinants of survival of people living with HIV/AIDS on antiretroviral therapy in Brazil 2006-2015 by Mangal, Tara D, Meireles, Mariana Veloso, Pascom, Ana Roberta Pati, de Almeida Coelho, Ronaldo, Benzaken, Adele Schwartz, Hallett, Timothy B

“…We compared AIDS-related mortality rates in people living with HIV (PLHIV) starting antiretroviral therapy (ART) in Brazil during 2006-2015 and examined…”
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