Search Results - "Haller, Michael J"

Modeling the progression of Type 2 diabetes with underlying obesity by Yang, Boya, Li, Jiaxu, Haller, Michael J, Schatz, Desmond A, Rong, Libin

“…Environmentally induced or epigenetic-related beta-cell dysfunction and insulin resistance play a critical role in the progression to diabetes. We developed a…”
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Evidence of a Strong Association Between Frequency of Self-Monitoring of Blood Glucose and Hemoglobin A1c Levels in T1D Exchange Clinic Registry Participants by MILLER, Kellee M, BECK, Roy W, BERGENSTAL, Richard M, GOLAND, Robin S, HALLER, Michael J, MCGILL, Janet B, RODRIGUEZ, Henry, SIMMONS, Jill H, HIRSCH, Irl B

“…Despite substantial evidence of the benefit of frequent self-monitoring of blood glucose (SMBG) in type 1 diabetes, certain insurers limit the number of test…”
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The influence of type 1 diabetes on pancreatic weight by Campbell-Thompson, Martha L., Kaddis, John S., Wasserfall, Clive, Haller, Michael J., Pugliese, Alberto, Schatz, Desmond A., Shuster, Jonathan J., Atkinson, Mark A.

“…Aims/hypothesis Previous studies of pancreases obtained at autopsy or by radiography note reduced pancreas weight (PW) and size, respectively, in type 1…”
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Reduced Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up by Elding Larsson, Helena, Vehik, Kendra, Bell, Ronny, Dabelea, Dana, Dolan, Lawrence, Pihoker, Catherine, Knip, Mikael, Veijola, Riitta, Lindblad, Bengt, Samuelsson, Ulf, Holl, Reinhard, Haller, Michael J

“…OBJECTIVE: Young children have an unacceptably high prevalence of diabetic ketoacidosis (DKA) at the clinical diagnosis of type 1 diabetes. The aim of this…”
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Prevalence of detectable C-Peptide according to age at diagnosis and duration of type 1 diabetes by Davis, Asa K, DuBose, Stephanie N, Haller, Michael J, Miller, Kellee M, DiMeglio, Linda A, Bethin, Kathleen E, Goland, Robin S, Greenberg, Ellen M, Liljenquist, David R, Ahmann, Andrew J, Marcovina, Santica M, Peters, Anne L, Beck, Roy W, Greenbaum, Carla J

“…It is generally accepted that complete β-cell destruction eventually occurs in individuals with type 1 diabetes, which has implications for treatment…”
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The progression of secondary diabetes: A review of modeling studies by Yang, Boya, Li, Jiaxu, Haller, Michael J, Schatz, Desmond A, Rong, Libin

“…Mathematical modeling has provided quantitative information consistent with experimental data, greatly improving our understanding of the progression of type 1…”
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Insulin-Like Growth Factor Dysregulation Both Preceding and Following Type 1 Diabetes Diagnosis by Shapiro, Melanie R, Wasserfall, Clive H, McGrail, Sean M, Posgai, Amanda L, Bacher, Rhonda, Muir, Andrew, Haller, Michael J, Schatz, Desmond A, Wesley, Johnna D, von Herrath, Matthias, Hagopian, William A, Speake, Cate, Atkinson, Mark A, Brusko, Todd M

“…Insulin-like growth factors (IGFs), specifically IGF1 and IGF2, promote glucose metabolism, with their availability regulated by IGF-binding proteins (IGFBPs)…”
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Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes by Balzano-Nogueira, Leandro, Ramirez, Ricardo, Zamkovaya, Tatyana, Dailey, Jordan, Ardissone, Alexandria N, Chamala, Srikar, Serrano-Quílez, Joan, Rubio, Teresa, Haller, Michael J, Concannon, Patrick, Atkinson, Mark A, Schatz, Desmond A, Triplett, Eric W, Conesa, Ana

“…The Environmental Determinants of Diabetes in the Young (TEDDY) is a prospective birth cohort designed to study type 1 diabetes (T1D) by following children…”
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Acute Versus Progressive Onset of Diabetes in NOD Mice: Potential Implications for Therapeutic Interventions in Type 1 Diabetes by Mathews, Clayton E, Xue, Song, Posgai, Amanda, Lightfoot, Yaima L, Li, Xia, Lin, Andrea, Wasserfall, Clive, Haller, Michael J, Schatz, Desmond, Atkinson, Mark A

“…Most natural history models for type 1 diabetes (T1D) propose that overt hyperglycemia results after a progressive loss of insulin-secreting β-cell mass and/or…”
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Understanding Pre-Type 1 Diabetes: The Key to Prevention by Jacobsen, Laura M, Haller, Michael J, Schatz, Desmond A

“…While the incidence of type 1 diabetes continues to rise by 3% each year, the ability to prevent this disease remains elusive. Hybrid closed loop devices,…”
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Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood by Motwani, Keshav, Peters, Leeana D, Vliegen, Willem H, El-Sayed, Ahmed Gomaa, Seay, Howard R, Lopez, M Cecilia, Baker, Henry V, Posgai, Amanda L, Brusko, Maigan A, Perry, Daniel J, Bacher, Rhonda, Larkin, Joseph, Haller, Michael J, Brusko, Todd M

“…The human T lymphocyte compartment is highly dynamic over the course of a lifetime. Of the many changes, perhaps most notable is the transition from a…”
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Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults by Marcial, Guillermo E, Ford, Amanda L, Haller, Michael J, Gezan, Salvador A, Harrison, Natalie A, Cai, Dan, Meyer, Julie L, Perry, Daniel J, Atkinson, Mark A, Wasserfall, Clive H, Garrett, Timothy, Gonzalez, Claudio F, Brusko, Todd M, Dahl, Wendy J, Lorca, Graciela L

“…N6.2 mitigates the onset of type 1 diabetes (T1D) in biobreeding diabetes-prone rats, in part, through changes in kynurenine:tryptophan (K:T) ratios. The goal…”
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Recruiting historically under-represented individuals into Project ECHO Diabetes: using barrier analysis to understand disparities in clinical research in the USA by Addala, Ananta, Hechavarria, Melanie, Figg, Lauren, Roque, Xanadu, Filipp, Stephanie L, Anez-Zabala, Claudia, Lal, Rayhan, Gurka, Matthew J, Haller, Michael J, Maahs, David M, Walker, Ashby F

“…Individuals under-recruited in diabetes research studies include those not seen at endocrinology centres and those from rural, low socioeconomic and/or…”
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Diabetic Ketoacidosis at Diabetes Onset: Still an All Too Common Threat in Youth by Klingensmith, Georgeanna J., MD, Tamborlane, William V., MD, Wood, Jamie, MD, Haller, Michael J., MD, Silverstein, Janet, MD, Cengiz, Eda, MD, Shanmugham, Satya, BS, Kollman, Craig, PhD, Wong-Jacobson, Siew, MPH, Beck, Roy W., MD, PhD

“…Objective To define the demographic and clinical characteristics of children at the onset of type 1 diabetes (T1D), with particular attention to the frequency…”
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Type 1 Diabetes: Current Concepts in Epidemiology, Pathophysiology, Clinical Care, and Research by Gan, Mary Joyce, MD, Albanese-O’Neill, Anastasia, RN, CDE, Haller, Michael J., MD

“…Type 1 diabetes (T1D) is an autoimmune disease mediated by a combination of genetic and environmental triggers resulting in lymphocytic infiltration of…”
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Type 1 diabetes prevention clinical trial simulator: Case reports of model‐informed drug development tool by Morales, Juan Francisco, Klose, Marian, Hoffert, Yannick, Podichetty, Jagdeep T., Burton, Jackson, Schmidt, Stephan, Romero, Klaus, O'Doherty, Inish, Martin, Frank, Campbell‐Thompson, Martha, Haller, Michael J., Atkinson, Mark A., Kim, Sarah

“…Clinical trials seeking to delay or prevent the onset of type 1 diabetes (T1D) face a series of pragmatic challenges. Despite more than 100 years since the…”
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Sociodemographic factors associated with major depressive episodes and suicidal ideation among emerging adults with diabetes in the U.S by Yadav, Sandhya, Hong, Young-Rock, Westen, Sarah, Marlow, Nicole M, Haller, Michael J, Walker, Ashby F

“…Research focused on disparities related to mental health comorbidities, especially among emerging adults with diabetes, is limited. Identifying associated…”
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Disease progression joint model predicts time to type 1 diabetes onset: Optimizing future type 1 diabetes prevention studies by Morales, Juan Francisco, Muse, Rhoda, Podichetty, Jagdeep T., Burton, Jackson, David, Sarah, Lang, Patrick, Schmidt, Stephan, Romero, Klaus, O'Doherty, Inish, Martin, Frank, Campbell‐Thompson, Martha, Haller, Michael J., Atkinson, Mark A., Kim, Sarah

“…Clinical trials seeking type 1 diabetes prevention are challenging in terms of identifying patient populations likely to progress to type 1 diabetes within…”
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Tele-education model for primary care providers to advance diabetes equity: Findings from Project ECHO Diabetes by Addala, Ananta, Filipp, Stephanie L, Figg, Lauren E, Anez-Zabala, Claudia, Lal, Rayhan A, Gurka, Matthew J, Haller, Michael J, Maahs, David M, Walker, Ashby F

“…In the US, many individuals with diabetes do not have consistent access to endocrinologists and therefore rely on primary care providers (PCPs) for their…”
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Democratizing type 1 diabetes specialty care in the primary care setting to reduce health disparities: project extension for community healthcare outcomes (ECHO) T1D by Walker, Ashby F, Cuttriss, Nicolas, Haller, Michael J, Hood, Korey K, Gurka, Matthew J, Filipp, Stephanie L, Anez-Zabala, Claudia, Yabut, Katarina, Roque, Xanadu, Wong, Jessie J, Baer, Linda, Figg, Lauren, Bernier, Angelina, Westen, Sarah, Lewit, Eugene, Sheehan, Eleni, Basina, Marina, Lal, Rayhan, Maizel, Jennifer, Maahs, David M

“…IntroductionProject ECHO (Extension for Community Healthcare Outcomes) is a tele-education outreach model that seeks to democratize specialty knowledge to…”
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