Search Results - "Haller, Jorge F."

ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance[S] by Haller, Jorge F., Mintah, Ivory J., Shihanian, Lisa M., Stevis, Panayiotis, Buckler, David, Alexa-Braun, Corey A., Kleiner, Sandra, Banfi, Serena, Cohen, Jonathan C., Hobbs, Helen H., Yancopoulos, George D., Murphy, Andrew J., Gusarova, Viktoria, Gromada, Jesper

“…Angiopoietin-like (ANGPTL)3 and ANGPTL8 are secreted proteins and inhibitors of LPL-mediated plasma triglyceride (TG) clearance. It is unclear how these two…”
Get full text

Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes by Krawczyk, Sarah A, Haller, Jorge F, Ferrante, Tom, Zoeller, Raphael A, Corkey, Barbara E

“…In obesity, there is an increase in reactive oxygen species (ROS) within adipose tissue caused by increases in inflammation and overnutrition. Hormone…”
Get full text

Exome Sequencing in Suspected Monogenic Dyslipidemias by Stitziel, Nathan O, Peloso, Gina M, Abifadel, Marianne, Cefalu, Angelo B, Fouchier, Sigrid, Motazacker, M Mahdi, Tada, Hayato, Larach, Daniel B, Awan, Zuhier, Haller, Jorge F, Pullinger, Clive R, Varret, Mathilde, Rabès, Jean-Pierre, Noto, Davide, Tarugi, Patrizia, Kawashiri, Masa-aki, Nohara, Atsushi, Yamagishi, Masakazu, Risman, Marjorie, Deo, Rahul, Ruel, Isabelle, Shendure, Jay, Nickerson, Deborah A, Wilson, James G, Rich, Stephen S, Gupta, Namrata, Farlow, Deborah N, Neale, Benjamin M, Daly, Mark J, Kane, John P, Freeman, Mason W, Genest, Jacques, Rader, Daniel J, Mabuchi, Hiroshi, Kastelein, John J.P, Hovingh, G Kees, Averna, Maurizio R, Gabriel, Stacey, Boileau, Catherine, Kathiresan, Sekar

“…BACKGROUND—Exome sequencing is a promising tool for gene mapping in Mendelian disorders. We used this technique in an attempt to identify novel genes…”
Get full text

Endogenous β-glucocerebrosidase activity in Abca12−/−epidermis elevates ceramide levels after topical lipid application but does not restore barrier function by Haller, Jorge F., Cavallaro, Paul, Hernandez, Nicholas J., Dolat, Lee, Soscia, Stephanie J., Welti, Ruth, Grabowski, Gregory A., Fitzgerald, Michael L., Freeman, Mason W.

“…ABCA12 mutations disrupt the skin barrier and cause harlequin ichthyosis. We previously showed Abca12−/− skin has increased glucosylceramide (GlcCer) and…”
Get full text

Isolation of Novel Animal Cell Lines Defective in Glycerolipid Biosynthesis Reveals Mutations in Glucose-6-phosphate Isomerase by Haller, Jorge F., Smith, Conor, Liu, Dailan, Zheng, Hongying, Tornheim, Keith, Han, Gil-Soo, Carman, George M., Zoeller, Raphael A.

“…Glycerolipids are structural components for membranes and serve in energy storage. We describe here the use of a photodynamic selection technique to generate a…”
Get full text

Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1α to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease by Haller, Jorge F., Krawczyk, Sarah A., Gostilovitch, Lubov, Corkey, Barbara E., Zoeller, Raphael A.

“…Inherited glucose-6-phosphate isomerase (GPI) deficiency is the second most frequent glycolytic erythroenzymopathy in humans. Patients present with…”
Get full text

A Three-dimensional Model of the Human Facilitative Glucose Transporter Glut1 by Zuniga, F A, Shi, G, Haller, J F, Rubashkin, A, Flynn, D R, Iserovich, P, Fischbarg, J

“…The human facilitative transporter Glut1 is the major glucose transporter present in all human cells, has a central role in metabolism, and is an archetype of…”
Get full text

Optical characterization of armadillo Acyl-CoA binding protein by Cavagnari, Brian M, Milikowski, Daniel, Haller, Jorge F, Zanek, Marı́a C, Santomé, José A, Ermácora, Mario R

“…Acyl-CoA binding protein (ACBP) and fatty acid binding protein (FABP) are intracellular transporters of activated and free fatty acids, respectively. Unlike…”
Get full text

Presence of a Fatty Acid-Binding Protein and Lipid Stores in Flight Muscles of Dipetalogaster maximus (Hemiptera: Reduviidae) by Cavagnari, Brian M., Scaraffia, Patricia Y., Haller, Jorge F., Gerez de Burgos, Nelia M., Santomé, José A.

“…A fatty acid-binding protein (FABP) from the cytosolic fraction of the triatomine Dipetalogaster maximus (Uhler) flight muscles was purified by a procedure…”
Get full text

Endogenous β-glucocerebrosidase activity in Abca12epidermis elevates ceramide levels after topical lipid application but does not restore barrier function by Haller, Jorge F., Cavallaro, Paul, Hernandez, Nicholas J., Dolat, Lee, Soscia, Stephanie J., Welti, Ruth, Grabowski, Gregory A., Fitzgerald, Michael L., Freeman, Mason W.

Get full text

Mercurial sensitivity of aquaporin 1 endofacial loop B residues by Kuang, Kunyan, Haller, Jorge F., Shi, Guangpu, Kang, Fengying, Cheung, Min, Iserovich, Pavel, Fischbarg, Jorge

“…The water channel protein aquaporin‐1 (AQP1) has two asparagine‐proline‐alanine (NPA) repeats on loops B and E. From recent structural information, these loops…”
Get full text