Search Results - "Halle, J"
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Microbiome‐immune‐metabolic axis in the epidemic of childhood obesity: Evidence and opportunities
Published in Obesity reviews (01-02-2020)“…Summary Obesity epidemic responsible for increase in diabetes, heart diseases, infections and cancer shows no signs of abating. Obesity in children is also on…”
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Diet-Microbiota-Brain Axis in Alzheimer's Disease
Published in Annals of nutrition and metabolism (01-10-2021)“…Alzheimer's disease (AD) is the most common form of dementia, particularly in older adults, with clinical manifestations of progressive cognitive decline and…”
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Inhalable Stem Cell Exosomes Promote Heart Repair After Myocardial Infarction
Published in Circulation (New York, N.Y.) (27-08-2024)“…Exosome therapy shows potential for cardiac repair after injury. However, intrinsic challenges such as short half-life and lack of clear targets hinder the…”
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Infanticide in a mammal-eating killer whale population
Published in Scientific reports (20-03-2018)“…Infanticide can be an extreme result of sexual conflict that drives selection in species in which it occurs. It is a rarely observed behaviour but some…”
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USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
Published in Molecular cancer research (01-11-2023)“…In this study, we identify USP1 as a transcriptional target of EWS::FLI1 and demonstrate the requisite function of USP1 in Ewing sarcoma (EWS) cell survival in…”
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Co-encapsulation of bioengineered IGF-II-producing cells and pancreatic islets: effect on beta-cell survival
Published in Gene therapy (01-06-2011)“…Insulin-like growth factor-II (IGF-II) has been shown to promote pancreatic β-cell survival. We evaluated the effect of co-encapsulating islets and…”
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Retrospective Analysis of a STEM Outreach Event Reveals Positive Influences on Student Attitudes toward STEM Careers but Not Scientific Methodology
Published in Advances in physiology education (01-09-2021)“…Substantial, involved, and expensive efforts to promote the dissemination of scientific knowledge and career interest in Science, Technology, Engineering, and…”
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A preoperative predictive tool to assess the need for staging laparoscopy in oesophagogastric cancer patients
Published in Annals of the Royal College of Surgeons of England (01-04-2024)“…Staging laparoscopy (SL) has become commonplace in the preoperative staging pathway for oesophagogastric (OG) cancer. SL is often performed before curative…”
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Urgent surgical repair of symptomatic Bochdalek hernia containing an intrathoracic kidney
Published in Annals of the Royal College of Surgeons of England (01-01-2021)“…Bochdalek hernias rarely contain an intrathoracic kidney, and there are few reports of their operative repair. A woman presented with progressive dyspnoea…”
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Biocompatibility and physicochemical characteristics of alginate–polycation microcapsules
Published in Acta biomaterialia (01-04-2011)“…There is a need for better understanding of the biocompatibility of alginate–polycation microcapsules based on their physicochemical characteristics…”
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Long-term comparison of losartan and enalapril on kidney function in hypertensive type 2 diabetics with early nephropathy
Published in Kidney international (01-08-2000)“…Long-term comparison of losartan and enalapril on kidney function in hypertensive type 2 diabetics with early nephropathy. The objectives of this study were to…”
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Therapeutic cell encapsulation techniques and applications in diabetes
Published in Advanced drug delivery reviews (01-04-2014)“…The encapsulation of therapeutic cells permits the implantation of allogeneic and xenogeneic cells for the regulation of certain physiological processes…”
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Albuminuria and Risk of Cardiovascular Events, Death, and Heart Failure in Diabetic and Nondiabetic Individuals
Published in JAMA : the journal of the American Medical Association (25-07-2001)“…CONTEXT Microalbuminuria is a risk factor for cardiovascular (CV) events. The relationship between the degree of albuminuria and CV risk is unclear. OBJECTIVES…”
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The Ca2+-binding Proteins S100A8 and S100A9 Are Encoded by Novel Injury-regulated Genes
Published in The Journal of biological chemistry (21-09-2001)“…To gain insight into the molecular mechanisms underlying cutaneous wound repair, we performed a large scale screen to identify novel injury-regulated genes…”
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A thematic review of scientific and family interests in Canavan Disease: where are the developmentalists?
Published in Journal of intellectual disability research (01-09-2013)“…Background Canavan Disease is a degenerative neurological condition resulting in a spongy deterioration of the brain. Much research has been conducted by the…”
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Similar progression of diabetic retinopathy with insulin glargine and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes: a long-term, randomised, open-label study
Published in Diabetologia (01-09-2009)“…Aims/hypothesis This long-term study was designed to further characterise the retinal safety profile of insulin glargine and human neutral protamine Hagedorn…”
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WE‐C‐BRA‐04: Left Breast Deep Inspiration Breath Hold Treatment Based on 3D Surface Matching
Published in Medical Physics (01-06-2011)“…Deep inspiration breath hold (DIBH) is a cardiac sparing technique to treat left‐sided breast cancer. By supervising a patient holding her breath at the deep…”
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MO‐F‐BRC‐04: Is the External Point/marker a Good Surrogate for the Breast Surface Motion during the Left Breast DIBH Treatment?
Published in Medical Physics (01-06-2011)“…Purpose: The ideal way of treating left breast DIBH is through direct breast surface matching. Many DIBH techniques, however, rely on a surrogate—external…”
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