Search Results - "Hallam, T M"

Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic by Hallam, T.M., Sharp, S.J., Andreadi, A., Kavanagh, D.

“…Complement factor I (FI) is the nexus for classical, lectin and alternative pathway complement regulation. FI is an 88 kDa plasma protein that circulates in an…”
Get full text

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade by McMahon, O, Hallam, T M, Patel, S, Harris, C L, Menny, A, Zelek, W M, Widjajahakim, R, Java, A, Cox, T E, Tzoumas, N, Steel, D H W, Shuttleworth, V G, Smith-Jackson, K, Brocklebank, V, Griffiths, H, Cree, A J, Atkinson, J P, Lotery, A J, Bubeck, D, Morgan, B P, Marchbank, K J, Seddon, J M, Kavanagh, D

“…Abstract Age-related macular degeneration (AMD) is a complex neurodegenerative eye disease with behavioral and genetic etiology and is the leading cause of…”
Get full text

Rubinstein-Taybi syndrome: molecular findings and therapeutic approaches to improve cognitive dysfunction by Hallam, T M, Bourtchouladze, R

“…Rubinstein-Taybi syndrome (RTS) is a rare human genetic disorder characterized by mental retardation and physical abnormalities. Many RTS patients have a…”
Get full text

Comparison of behavioral deficits and acute neuronal degeneration in rat lateral fluid percussion and weight-drop brain injury models by Hallam, Thomas M, Floyd, Candace L, Folkerts, Michael M, Lee, Lillian L, Gong, Q-Z, Lyeth, Bruce G, Muizelaar, J Paul, Berman, Robert F

“…The behavioral and histological effects of the lateral fluid percussion (LFP) brain injury model were compared with the weight drop impact-acceleration model…”
Get more information