Search Results - "Hallam, Catherine"

Understanding tablet defects in commercial manufacture and transfer by Sabri, Akmal H., Hallam, Catherine N., Baker, Noel A., Murphy, Dean S., Gabbott, Ian P.

“…The effect of tablet tensile strength, drop height, number of drops and formulation on the propensity of tablet defects was investigated using modified tablet…”
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Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A2 Based on a 1,3-Disubstituted Propan-2-one Skeleton by Connolly, Stephen, Bennion, Colin, Botterell, Sarah, Croshaw, Pamela J, Hallam, Catherine, Hardy, Kim, Hartopp, Paul, Jackson, Clive G, King, Sarah J, Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H, Smith, Gillian M, Stein, Linda, Walters, Iain, Wells, Edward, Withnall, W. John

“…Using knowledge of the substrate specificity of cPLA2 (phospholipases A2), a novel series of inhibitors of this enzyme were designed based upon a three point…”
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Increasing tensile strength by reducing particle size for extrudate-based tablet formulations by Hallam, Catherine N., Gabbott, Ian P.

“…The effect of milled extrudate particle size on tablet tensile strength was investigated in this study. Parameters used for milling with a hammer impact mill…”
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Corrigendum to “Understanding tablet defects in commercial manufacture and transfer” [J. Drug Delivery Sci. Technol. 46 (2018) 1–6] by Sabri, Akmal H., Hallam, Catherine N., Baker, Noel A., Murphy, Dean S., Gabbott, Ian P.

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Antianxiety properties of the angiotensin II antagonist, DUP 753, in the rat using the elevated plus-maze by Kaiser, F C, Palmer, G C, Wallace, A V, Carr, R D, Fraser-Rae, L, Hallam, C

“…The angiotensin II receptor antagonist, DUP 753 (Losartan), was compared with diazepam for antianxiety properties in the rat using the elevated plus-maze. Oral…”
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Defect passivation on cast-mono crystalline screen-printed cells by WENHAM, Alison, SONG, Lihui, ABBOTT, Malcolm, ZAFIROVSKA, Iskra, WANG, Sisi, HALLAM, Brett, CHAN, Catherine, BARNETT, Allen, WENHAM, Stuart

“…Cast-mono crystalline silicon wafers contain crystallographic defects, which can severely impact the electrical performance of solar cells. This paper demon-…”
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Teachers' viewpoints of strategies to prevent school exclusion: a q methodological study by Hallam, Catherine Ann

“…School exclusion is a complex topic and receives ongoing attention nationally (Children’s Commissioner, 2012; Department for Education, 2013). A variety of…”
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Design and synthesis of a novel and potent series of inhibitors of cytosolic phospholipase A(2) based on a 1,3-disubstituted propan-2-one skeleton by Connolly, Stephen, Bennion, Colin, Botterell, Sarah, Croshaw, Pamela J, Hallam, Catherine, Hardy, Kim, Hartopp, Paul, Jackson, Clive G, King, Sarah J, Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H, Smith, Gillian M, Stein, Linda, Walters, Iain, Wells, Edward, Withnall, W John

“…Using knowledge of the substrate specificity of cPLA(2) (phospholipases A(2)), a novel series of inhibitors of this enzyme were designed based upon a three…”
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Dual D2-Receptor and β2-Adrenoceptor Agonists for the Treatment of Airway Diseases. 1. Discovery and Biological Evaluation of Some 7-(2-Aminoethyl)- 4-hydroxybenzothiazol-2(3H)-one Analogues by Bonnert, Roger V, Brown, Roger C, Chapman, David, Cheshire, David R, Dixon, John, Ince, Francis, Kinchin, Elizabeth C, Lyons, Amanda J, Davis, Andrew M, Hallam, Catherine, Harper, Stephen T, Unitt, John F, Dougall, Iain G, Jackson, Dale M, McKechnie, Kenneth, Young, Alan, Simpson, Wilfred T

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Design and Synthesis of a Novel and Potent Series of Inhibitors of Cytosolic Phospholipase A 2 Based on a 1,3-Disubstituted Propan-2-one Skeleton by Connolly, Stephen, Bennion, Colin, Botterell, Sarah, Croshaw, Pamela J., Hallam, Catherine, Hardy, Kim, Hartopp, Paul, Jackson, Clive G., King, Sarah J., Lawrence, Louise, Mete, Antonio, Murray, David, Robinson, David H., Smith, Gillian M., Stein, Linda, Walters, Iain, Wells, Edward, Withnall, W. John

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Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2 by Beaton, Haydn G, Bennion, Colin, Connolly, Stephen, Cook, Anthony R, Gensmantel, Nigel P, Hallam, Catherine, Hardy, Kim, Hitchin, Barbara, Jackson, Clive G, Robinson, David H

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Dual D 2 -Receptor and β 2 -Adrenoceptor Agonists for the Treatment of Airway Diseases. 1. Discovery and Biological Evaluation of Some 7-(2-Aminoethyl)- 4-hydroxybenzothiazol-2(3 H )-one Analogues by Bonnert, Roger V., Brown, Roger C., Chapman, David, Cheshire, David R., Dixon, John, Ince, Francis, Kinchin, Elizabeth C., Lyons, Amanda J., Davis, Andrew M., Hallam, Catherine, Harper, Stephen T., Unitt, John F., Dougall, Iain G., Jackson, Dale M., McKechnie, Kenneth, Young, Alan, Simpson, Wilfred T.

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Design and synthesis of some substrate analog inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex by Bennion, Colin, Connolly, Stephen, Gensmantel, Nigel P, Hallam, Catherine, Jackson, Clive G, Primrose, William U, Roberts, Gordon C. K, Robinson, David H, Slaich, Pritpal K

“…A series of substrate analogue inhibitors of pancreatic phospholipase A2 has been designed and synthesized. The compounds were tested in a novel dual-screening…”
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Bombesin stimulates the rapid activation of phospholipase A2-catalyzed phosphatidylcholine hydrolysis in Swiss 3T3 cells by CURRIE, S, SMITH, G. L, CRICHTON, C. A, JACKSON, C. G, HALLAM, C, WAKELAM, M. J. O

“…In Swiss 3T3 fibroblasts bombesin stimulated the release of arachidonic acid in a time- and dose-dependent manner. Arachidonate levels were significantly…”
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(R)-2-(3-mercapto-2(S)-methyl-1-oxopropoxy)-3-(methylthio)propanoic acid (FPL 66564), the first ultra-short-acting angiotensin converting enzyme inhibitor by Baxter, Andrew J. G, Carr, Richard D, Eyley, Stephen C, Fraser-Rae, Lynne, Hallam, Catherine, Harper, Steve T, Hurved, Paul A, King, Sarah J, Meghani, Premji

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