Search Results - "Hallén, S."

Organization of the Membrane Domain of the Human Liver Sodium/Bile Acid Cotransporter by Hallén, S, Mareninova, O, Brändén, M, Sachs, G

“…Mammalian sodium/bile acid cotransporters (SBATs) are glycoproteins with an exoplasmic N-terminus, an odd number of transmembrane regions, and a cytoplasmic…”
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Identification of a Region of the Ileal-Type Sodium/Bile Acid Cotransporter Interacting with a Competitive Bile Acid Transport Inhibitor by Hallén, S, Björquist, A, Östlund-Lindqvist, A. M, Sachs, G

“…Drug intervention that prevents reabsorption of circulating bile acids by the apical (ileal) sodium/bile acid cotransporter (ASBT) may be a promising new…”
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Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes by Harms, Matthew J., Li, Qian, Lee, Sunjae, Zhang, Cheng, Kull, Bengt, Hallen, Stefan, Thorell, Anders, Alexandersson, Ida, Hagberg, Carolina E., Peng, Xiao-Rong, Mardinoglu, Adil, Spalding, Kirsty L., Boucher, Jeremie

“…White adipose tissue (WAT) is a central factor in the development of type 2 diabetes, but there is a paucity of translational models to study mature…”
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Cell-based multiwell assays for the detection of substrate accumulation and oxidation by Wensaas, A.J, Rustan, A.C, Lövstedt, K, Kull, B, Wikström, S, Drevon, C.A, Hallén, S

“…We describe multiwell assays for detecting the accumulation as well as the subsequent oxidation of ¹⁴C-labeled substrates in cultured cells. Accumulation is…”
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Cell-based multiwell assays for the detection of substrate accumulation and oxidation1 by Wensaas, A.J., Rustan, A.C., Lövstedt, K., Kull, B., Wikström, S., Drevon, C.A., Hallén, S.

“…We describe multiwell assays for detecting the accumulation as well as the subsequent oxidation of 14C-labeled substrates in cultured cells. Accumulation is…”
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Proton transfer during the reaction between fully reduced cytochrome c oxidase and dioxygen: pH and deuterium isotope effects by Hallen, Stefan, Nilsson, Thomas

“…The pH dependence of proton uptake and electron transfers during the reaction between fully reduced cytochrome c oxidase and oxygen has been studied using the…”
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Light-induced structural changes in cytochrome c oxidase: implication for the mechanism of electron and proton gating by Hallén, S, Brzezinski, P

“…We have investigated electrogenic events and absorbance changes following pulsed illumination of partly reduced cytochrome c oxidase in the absence of dioxygen…”
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Internal Electron Transfer in Cytochrome c Oxidase Is Coupled to the Protonation of a Group Close to the Bimetallic Site by Hallen, Stefan, Brzezinski, Peter, Malmstroem, Bo G

“…Absorbance changes following CO dissociation by flash photolysis from mixed-valence cytochrome oxidase have been followed in the Soret and alpha regions. Apart…”
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Uptake and release of protons during the reaction between cytochrome c oxidase and molecular oxygen: a flow-flash investigation by Oliveberg, Mikael, Hallen, Stefan, Nilsson, Thomas

“…Changes in pH during the reactions of the fully reduced and mixed-valence cytochrome oxidase with molecular oxygen have been followed in flow-flash…”
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Light-induced structural changes in cytochrome c oxidase : Measurements of electrogenic events and absorbance changes by Hallén, Stefan, Oliveberg, Mikael, Brzezinski, Peter

“…We have investigated flash-induced electrogenic events and absorbance changes in cytochrome c oxidase in the absence of dioxygen and carbon monoxide…”
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Cytochrome bo from E. coli does not exhibit the same proton transfer characteristics as the bovine cytochrome c oxidase during oxygen reduction by Hallén, Stefan, Svensson, Margareta, Nilsson, Thomas

“…The reaction where fully reduced cytochrome bo from E. coli partially reduces dioxygen has been characterized with respect to the kinetics of the associated…”
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Inhibition of the Human Sodium/Bile Acid Cotransporters by Side-Specific Methanethiosulfonate Sulfhydryl Reagents:  Substrate-Controlled Accessibility of Site of Inactivation by Hallén, Stefan, Fryklund, Jan, Sachs, George

“…Mammalian sodium/bile acid cotransporters (SBATs) constitute a subgroup of the sodium cotransporter superfamily and function in the enterohepatic circulation…”
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Kinetic Coupling between Electron and Proton Transfer in Cytochrome c Oxidase: Simultaneous Measurements of Conductance and Absorbance Changes by Adelroth, Pia, Sigurdson, Hakan, Hallen, Stefan, Brzezinski, Peter

“…Bovine heart cytochrome c oxidase is an electron-current driven proton pump. To investigate the mechanism by which this pump operates it is important to study…”
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Membrane Insertion Scanning of the Human Ileal Sodium/Bile Acid Co-transporter by Hallén, Stefan, Brändén, Magnus, Dawson, Paul A, Sachs, George

“…Mammalian sodium-dependent bile acid transporters (SBATs) responsible for bile salt uptake across the liver sinusoidal or ileal/renal brush border membrane…”
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Cytostar-T Scintillating Microplate Assay for Measurement of Sodium-Dependent Bile Acid Uptake in Transfected HEK-293 Cells by Bonge, Helena, Hallén, Stefan, Fryklund, Jan, Sjöström, Jan-Eric

“…Real-time measurements of bile acid uptake into HEK-293 cell monolayers expressing the human sodium/bile acid cotransporters have been demonstrated using…”
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Evaluation of the MaineHealth Skilled Nursing Facility Congestive Heart Failure Protocol by Hallen, Sarah, Hallen, S., Caminiti, M., Marino, R., Shao, E., Cannon, A., Veilleux, R., Dmytrasz, K., Wierman, H.

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The narrow proton beam therapy unit at the the Svedberg Laboratory in Uppsala by Montelius, A, Blomquist, E, Naeser, P, Brahme, A, Carlsson, J, Carlsson, A C, Graffman, S, Grusell, E, Hallén, S, Jakobsson, P

“…The synchrocyclotron at the The Svedberg Laboratory (TSL) in Uppsala is now reconstructed and can presently operate with fixed frequency and proton energies up…”
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Topography of the Membrane Domain of the Liver Na+-Dependent Bile Acid Transporter by Mareninova, Olga, Shin, Jai Moo, Vagin, Olga, Turdikulova, Shahlo, Hallen, Stefan, Sachs, George

“…The ileal apical and liver basolateral bile acid transporters catalyze the Na+-dependent uptake of these amphipathic molecules in the intestine and liver. They…”
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Oxygen Reaction and Proton Uptake in Helix VIII Mutants of Cytochrome bo3 by Svensson, Margareta, Hallen, Stefan, Thomas, Jeffrey W, Lemieux, Laura J, Gennis, Robert B, Nilsson, Thomas

“…The oxygen reaction of wild-type and helix VIII mutants of cytochrome bo3 from Escherichia coli, and the associated proton uptake during this reaction, has…”
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Safekeeping of drugs in lifeboats by HALLEN, S

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