Search Results - "Hall, Susan H"
-
1
Activation of Toll-Like Receptor 4 (TLR4) by In Vivo and In Vitro Exposure of Rat Epididymis to Lipopolysaccharide from Escherichia Coli
Published in Biology of reproduction (01-12-2008)“…This study provides the first evidence that rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia…”
Get full text
Journal Article -
2
Comparative profiling of genes and miRNAs expressed in the newborn, young adult, and aged human epididymides
Published in Acta biochimica et biophysica Sinica (01-02-2010)“…To understand roles of transcriptional factors and miRNAs in regulating gene expression in the epididymis from postnatal development through aging, systematic…”
Get full text
Journal Article -
3
Antimicrobial Activity of Human EPPIN, an Androgen-Regulated, Sperm-Bound Protein with a Whey Acidic Protein Motif
Published in Biology of reproduction (01-11-2004)“…The role of epididymal sperm-binding proteins in reproductive tract immunity is now well recognized in addition to their role in sperm maturation. Spermatozoa…”
Get full text
Journal Article -
4
Novel Partners of SPAG11B Isoform D in the Human Male Reproductive Tract
Published in Biology of reproduction (01-10-2009)“…Human sperm-associated antigen 11 (SPAG11) is closely related to beta-defensins in structure, expression, and function. Like the beta-defensins, SPAG11…”
Get full text
Journal Article -
5
RNase9, an Androgen-Dependent Member of the RNase A Family, Is Specifically Expressed in the Rat Epididymis
Published in Biology of reproduction (2007)“…Members of the RNase superfamily participate in a diverse array of biological processes, including RNA degradation, antipathogen activities, angiogenesis, and…”
Get full text
Journal Article -
6
Antimicrobial actions of the human epididymis 2 (HE2) protein isoforms, HE2alpha, HE2beta1 and HE2beta2
Published in Reproductive biology and endocrinology (24-08-2004)“…The HE2 gene encodes a group of isoforms with similarities to the antimicrobial beta-defensins. We demonstrated earlier that the antimicrobial activity of HE2…”
Get full text
Journal Article -
7
Cloning and primary characterizations of rLcn9, a new member of epididymal lipocalins in rat
Published in Acta biochimica et biophysica Sinica (01-10-2012)“…Lipocalins are a structurally conserved and diversely functional family of proteins that are of potential import- ance in epididymis functions. The rat Lcn9…”
Get full text
Journal Article -
8
Antimicrobial Actions of Human and Macaque Sperm Associated Antigen (SPAG) 11 Isoforms: influence of the N-terminal peptide
Published in Molecular and cellular biochemistry (01-03-2006)“…In addition to their role in sperm maturation, recent evidence has indicated that epididymal proteins have a role in male reproductive tract innate immunity…”
Get full text
Journal Article -
9
Identification, cloning and functional characterization of novel beta-defensins in the rat (Rattus norvegicus)
Published in Reproductive biology and endocrinology (04-02-2006)“…Beta-defensins are small cationic peptides that exhibit broad spectrum antimicrobial properties. The majority of beta-defensins identified in humans are…”
Get full text
Journal Article -
10
Cloning and sequencing of human Eppin: A novel family of protease inhibitors expressed in the epididymis and testis
Published in Gene (30-05-2001)“…In this report we describe the discovery of Eppin ( Epididymal protease inhibitor), a gene on human chromosome 20 expressing three mRNAs encoding two isoforms…”
Get full text
Journal Article -
11
Novel Aspects of the Sperm-Associated Antigen 11 (SPAG11) Gene Organization and Expression in Cattle (Bos taurus)
Published in Biology of reproduction (01-06-2007)“…Beta-defensins are small cationic peptides exhibiting broad spectrum antimicrobial properties. In humans, many beta-defensin genes are located within a cluster…”
Get full text
Journal Article -
12
Protein Inhibitors of Activated STAT Resemble Scaffold Attachment Factors and Function as Interacting Nuclear Receptor Coregulators
Published in The Journal of biological chemistry (10-05-2002)“…Protein inhibitor of activated STAT1 (PIAS1) functions as a nuclear receptor coregulator and is expressed in several cell types of human testis. However, the…”
Get full text
Journal Article -
13
Differential Expression and Antibacterial Activity of Epididymis Protein 2 Isoforms in the Male Reproductive Tract of Human and Rhesus Monkey (Macaca mulatta)
Published in Biology of reproduction (01-11-2004)“…The epididymis protein 2 (EP2) gene, the fusion of two ancestral β-defensin genes, is highly expressed in the epididymis and subject to species-specific…”
Get full text
Journal Article -
14
Activation of Toll-Like Receptor 4 (TLR4) by In Vivo and In Vitro Exposure of Rat Epididymis to Lipopolysaccharide from Escherichia Coli1
Published in Biology of reproduction (01-12-2008)“…This study provides the first evidence that rat epididymis is fully capable of initiating an inflammatory response to lipopolysaccharide (LPS) from Escherichia…”
Get full text
Journal Article -
15
Thyroid Receptor Activator Molecule, TRAM-1, Is an Androgen Receptor Coactivator
Published in Endocrinology (Philadelphia) (01-09-2000)“…Abstract An androgen receptor (AR) interacting protein was isolated from a HeLa cell complementary DNA library by two-hybrid screening in yeast using the AR…”
Get full text
Journal Article -
16
LCN6, a novel human epididymal lipocalin
Published in Reproductive biology and endocrinology (14-11-2003)“…The lipocalin (LCN) family of structurally conserved hydrophobic ligand binding proteins is represented in all major taxonomic groups from prokaryotes to…”
Get full text
Journal Article -
17
Antimicrobial host defence peptide, LL-37, as a potential vaginal contraceptive
Published in Human reproduction (Oxford) (01-04-2014)“…STUDY QUESTION Does antimicrobial peptide, LL-37, inhibit sperm fertilizing ability? SUMMARY ANSWER Our results indicate that LL-37 inhibits mouse and human…”
Get full text
Journal Article -
18
The Androgen-Regulated Epididymal Sperm-Binding Protein, Human β-Defensin 118 (DEFB118) (Formerly ESC42), Is an Antimicrobial β-Defensin
Published in Endocrinology (Philadelphia) (01-07-2004)“…Spermatozoa bind a variety of proteins as they pass through the proximal regions of the epididymis, where they acquire forward motility and fertilizing…”
Get full text
Journal Article -
19
Identification, cloning and functional characterization of novel sperm associated antigen 11 (SPAG11) isoforms in the rat
Published in Reproductive biology and endocrinology (28-04-2006)“…Sperm binding proteins and their C-terminal peptides of the Sperm Associated Antigen 11 (SPAG11) family were found to play an important role in epididymal…”
Get full text
Journal Article -
20
Characterization and functions of beta defensins in the epididymis
Published in Asian journal of andrology (01-07-2007)“…The epididymal β‐defensins have evolved by repeated gene duplication and divergence to encode a family of proteins that provide direct protection against…”
Get full text
Journal Article