Search Results - "Hall, Roger G."

The importance of trifluoromethyl pyridines in crop protection by Burriss, Adam, Edmunds, Andrew JF, Emery, Daniel, Hall, Roger G, Jacob, Olivier, Schaetzer, Jürgen

“…The pyridine ring, substituted by a trifluoromethyl substituent has been successfully incorporated into molecules with useful biological properties. During the…”
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Investigating the mode of action of sulfoxaflor: a fourth‐generation neonicotinoid by Cutler, Penny, Slater, Russell, Edmunds, Andrew JF, Maienfisch, Peter, Hall, Roger G, Earley, Fergus GP, Pitterna, Thomas, Pal, Sitaram, Paul, Verity‐Laura, Goodchild, Jim, Blacker, Melissa, Hagmann, Leonhard, Crossthwaite, Andrew J

“…BACKGROUND: The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor‐modulating insecticide, is unclear. A detailed understanding of…”
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Synthesis of CF3-Substituted Sulfoximines from Sulfonimidoyl Fluorides by Kowalczyk, Rafal, Edmunds, Andrew J. F, Hall, Roger G, Bolm, Carsten

“…N-Protected trifluoromethyl-substituted sulfoximines have been prepared by treatment of sulfonimidoyl fluorides with a combination of the Ruppert−Prakash…”
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Investigating the Structure-Activity Relationship of the Insecticidal Natural Product Rocaglamide by Hall, Roger G, Bruce, Ian, Cooke, Nigel G, Diorazio, Louis J, Cederbaum, Fredrik, Dobler, Markus R, Irving, Ed

“…The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection. In…”
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An Evaluation of the Use of Carbon Dioxide Angiography in Endovascular Aortic Aneurysm Repair by Lee, Arvind D., Hall, Roger G.

“…Introduction: Renal dysfunction after endovascular aortic aneurysm repair is an increasingly recognised problem. Carbon dioxide (CO2) angiography has been used…”
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The design and synthesis of biologically active organophosphorus compounds--the role of a central research laboratory by Hall, Roger G

“…The properties and benefits offered by incorporating phosphorus into molecules are varied and numerous as shown by the many divisional research programs within…”
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A Concise Synthesis of 3,5-Dicyano-6-trifluoromethylpyridine and Preparation of a Mono Thioamide by Hall, Roger G.

“…A concise 3-step synthesis of 3,5-dicyano-6-trifluoromethyl pyridine is reported from commercially available starting materials. Selective conversion of one…”
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Herbicidal 4-hydroxyphenylpyruvate dioxygenase inhibitors—A review of the triketone chemistry story from a Syngenta perspective by Beaudegnies, Renaud, Edmunds, Andrew J.F., Fraser, Torquil E.M., Hall, Roger G., Hawkes, Timothy R., Mitchell, Glynn, Schaetzer, Juergen, Wendeborn, Sebastian, Wibley, Jane

“…A review, outlining the origins and subsequent development of the triketone class of herbicidal 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors. A…”
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Synthesis and insecticidal activity of N-(5-phenylpyrazin-2-yl)-benzamide derivatives: Elucidation of mode of action on chitin biosynthesis through symptomology and genetic studies by Napolitano, Carmela, Benfatti, Fides, Hamdan, Farhan Bou, Bristow, Julia A., Dapiaggi, Federico, Firth, Lucy C., Guest, Marcus, Saunders, Helena A., Hall, Roger G., Monaco, Mattia R., Quetglas, Vincent, Rendine, Stefano, Eterovic, Marisa

“…Among the six-membered heterocycles, the pyrazine ring is poorly explored in crop protection and does not feature in any product listed in the current IRAC MoA…”
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Synthesis of 2,2-difluoro-3H-benzothiophen-3-ol via a difluorocarbene insertion reaction, investigating the scope for further derivatization by Rodrigues, Clarence, Hall, Roger G., Montgomery, Mark, Yang, Xiuhua, Xiang, Yong, Lu, Long, Pal, Sitaram, Manjunath, Bhanu N.

“…A simple, and efficient synthesis of 2,2-difluoro-3H-benzothiophen-3-ol using readily available sodium chlorodifluoroacetate (SCDA) is reported. We also…”
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Phosphinic Acid Analogs of GABA. 1. New Potent and Selective GABAB Agonists by Froestl, Wolfgang, Mickel, Stuart J, Hall, Roger G, von Sprecher, Georg, Strub, Dietrich, Baumann, Peter A, Brugger, Felix, Gentsch, Conrad, Jaekel, Joachim

“…The antispastic agent and muscle relaxant baclofen 1 is a potent and selective agonist for bicuculline-insensitive GABAB receptors. For many years efforts to…”
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Phosphinic Acid Analogs of GABA. 2. Selective, Orally Active GABAB Antagonists by Froestl, Wolfgang, Mickel, Stuart J, von Sprecher, Georg, Diel, Peter J, Hall, Roger G, Maier, Ludwig, Strub, Dietrich, Melillo, Vito, Baumann, Peter A

“…In 1987, 25 years after the synthesis of the potent and selective GABAB agonist baclofen (1), Kerr et al. described the first GABAB antagonist phaclofen 2…”
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The Importance of Fluorine in the Life Science Industry by Peter Maienfisch, Roger G. Hall

“…Fluorine-containing compounds are at the leading edge of many new developments in the life science industry. In recent years a steady increase in the number of…”
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Bicyclic heterocyclic anthranilic diamides as ryanodine receptor modulators with insecticidal activity by Jeanguenat, André, Durieux, Patricia, Edmunds, Andrew J.F., Hall, Roger G., Hughes, Dave, Loiseleur, Olivier, Pabba, Jagadish, Stoller, André, Trah, Stephan, Wenger, Jean, Dutton, Anna, Crossthwaite, Andrew

“…[Display omitted] The diamide insecticides act on the ryanodine receptor (RyR). The synthesis of various bicyclic anthranilic derivatives is reported. Their…”
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Total synthesis of (±)-rocaglamide and some aryl analogues by Dobler, Markus R, Bruce, Ian, Cederbaum, Fredrik, Cooke, Nigel G, Diorazio, Louis J, Hall, Roger G, Irving, Ed

“…The insecticidal activity found for rocaglamide and its congeners, prompted us to establish a short and efficient synthesis of the natural product and some…”
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Substituted α-(phenylhydrazono)phenylacetonitrile derivatives. Part 1: A new class of uncoupler of oxidative phosphorylation by Danko, Peter, Flury, Thomas, Hall, Roger G, Karrer, Friedrich, Kienast, Heinz, Kriz, Miroslav, Leuenberger, Katrin, Pascual, Alfons, Steiger, Arthur, Trah, Stephan

“…Substituted α‐(phenylhydrazono)phenylacetonitrile derivatives have been discovered which constitute a series of potent uncouplers of oxidative phosphorylation…”
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Synthesis of unsymmetrical dihydro triazine-2,4-diones by the N–N bond fragmentation of urazoles followed by intramolecular cyclization by Panga, Subhaskar R., Hall, Roger G., Samant, Rashmi V., Montgomery, Mark, Shyadligeri, Ashok S.

“…[Display omitted] A new synthesis of unsymmetrical dihydro triazine-2,4- diones has been accomplished, through the strategy of a base-induced fragmentation of…”
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Substituted α-(phenylhydrazono)phenylacetonitrile derivatives. Part 2: synthesis and biological activity of pro-pesticides by Flury, Thomas, Hall, Roger G, Karrer, Friedrich, Kienast, Heinz, Leuenberger, Katrin, Pascual, Alfons, Rindlisbacher, Alfred, Trah, Stephan, Widmer, Hans-Joerg

“…Pro‐pesticides of α‐(2,6‐dichloro‐4‐trifluoromethylphenylhydrazono)‐4‐nitrophenylacetonitrile have been prepared and tested against mite and insect pests…”
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CGP 35348: a centrally active blocker of GABAB receptors by Olpe, H R, Karlsson, G, Pozza, M F, Brugger, F, Steinmann, M, Van Riezen, H, Fagg, G, Hall, R G, Froestl, W, Bittiger, H

“…The biochemical, electrophysiological and pharmacological properties of the new GABAB receptor blocker CGP 35348 are described. In a variety of receptor…”
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Intermolecular coupling of 2-iodoanilides with benzoxazoles: synthesis of N-(2-Benzoxazol-2-ylphenyl)benzamides via C–H activation by Sasmal, Swarnendu, Sen, Indira, Hall, Roger G., Pal, Sitaram

“…[Display omitted] Using CuI/xantphos/Pd(OAc)2 catalytic system, the intermolecular C–C cross coupling between benzoxazoles and ortho-haloanilides has been…”
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