Search Results - "Hall, Nathan E."
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RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia
Published in Scientific reports (05-03-2021)“…Currently there is no consensus regarding the aetiology of the excessive ocular volume that characterizes high myopia. Thus, we aimed to test whether the gene…”
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Identification of Orthosteric and Allosteric Site Mutations in M2 Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias
Published in The Journal of biological chemistry (05-03-2010)“…Muscarinic acetylcholine receptors contain at least one allosteric site that is topographically distinct from the acetylcholine, orthosteric binding site…”
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Whole mitochondrial genome of the Ram’s Horn Squid shines light on the phylogenetic position of the monotypic order Spirulida (Haeckel, 1896)
Published in Molecular phylogenetics and evolution (01-04-2017)“…[Display omitted] •Spirulida, Bathyteuthoidea and Oegopsida form a monophyletic group.•Sepiidae is the sister taxon to a clade containing all extant…”
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Trophic ecology of Octopus vulgaris paralarvae along the Iberian Canary current eastern boundary upwelling system
Published in Scientific reports (30-05-2023)“…Our knowledge of the diet of wild octopus paralarvae, Octopus vulgaris, is restricted to the first 2 weeks of its planktonic phase when they are selective…”
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Bidirectional Expression of Metabolic, Structural, and Immune Pathways in Early Myopia and Hyperopia
Published in Frontiers in neuroscience (30-08-2016)“…Myopia (short-sightedness) affects 1.45 billion people worldwide, many of whom will develop sight-threatening secondary disorders. Myopic eyes are…”
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Comparative analysis of the predicted secretomes of Rosaceae scab pathogens Venturia inaequalis and V. pirina reveals expanded effector families and putative determinants of host range
Published in BMC genomics (02-05-2017)“…Fungal plant pathogens belonging to the genus Venturia cause damaging scab diseases of members of the Rosaceae. In terms of economic impact, the most important…”
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Combined Transcriptomic and Proteomic Analysis of the Posterior Salivary Gland from the Southern Blue-Ringed Octopus and the Southern Sand Octopus
Published in Journal of proteome research (02-09-2016)“…This study provides comprehensive proteomic profiles from the venom producing posterior salivary glands of octopus (superorder Octopodiformes) species. A…”
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A serine-arginine-rich (SR) splicing factor modulates alternative splicing of over a thousand genes in Toxoplasma gondii
Published in Nucleic acids research (19-05-2015)“…Single genes are often subject to alternative splicing, which generates alternative mature mRNAs. This phenomenon is widespread in animals, and observed in…”
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Age, Gender, and Laterality of Retinal Vascular Occlusion: A Retrospective Study from the IRIS® Registry
Published in Ophthalmology retina (01-02-2022)“…Retinal vascular occlusion is a leading cause of profound irreversible visual loss, but the understanding of the disease is insufficient. We systematically…”
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Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target
Published in Structure (London) (02-08-2016)“…Dihydrodipicolinate synthase (DHDPS) catalyzes the first committed step in the lysine biosynthesis pathway of bacteria. The pathway can be regulated by…”
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Exploring the utility of human DNA methylation arrays for profiling mouse genomic DNA
Published in Genomics (San Diego, Calif.) (01-07-2013)“…Illumina Infinium Human Methylation (HM) BeadChips are widely used for measuring genome-scale DNA methylation, particularly in relation to epigenome-wide…”
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A combined proteomic and transcriptomic analysis of slime secreted by the southern bottletail squid, Sepiadarium austrinum (Cephalopoda)
Published in Journal of proteomics (04-10-2016)“…Sepiadarium austrinum, the southern bottletail squid, is a small squid that inhabits soft sediments along Australia's south-east coast. When provoked, it…”
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PLAG1 deficiency impairs spermatogenesis and sperm motility in mice
Published in Scientific reports (13-07-2017)“…Deficiency in pleomorphic adenoma gene 1 (PLAG1) leads to reduced fertility in male mice, but the mechanism by which PLAG1 contributes to reproduction is…”
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Using Transcriptomics to Identify Differential Gene Expression in Response to Salinity among Australian Phragmites australis Clones
Published in Frontiers in plant science (13-04-2016)“…Common Reed (Phragmites australis) is a frequent component of inland and coastal wetlands in temperate zones worldwide. Ongoing environmental changes have…”
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Zebrafish SPI-1 (PU.1) Marks a Site of Myeloid Development Independent of Primitive Erythropoiesis: Implications for Axial Patterning
Published in Developmental biology (15-06-2002)“…The mammalian transcription factor SPI-1 (synonyms: SPI1, PU.1, or Sfpi1) plays a critical role in myeloid development. To examine early myeloid commitment in…”
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Identification of the Epitope for the Epidermal Growth Factor Receptor-specific Monoclonal Antibody 806 Reveals That It Preferentially Recognizes an Untethered Form of the Receptor
Published in The Journal of biological chemistry (16-07-2004)“…The epidermal growth factor receptor (EGFR) is overexpressed in many epithelial cancers, an observation often correlated with poor clinical outcome…”
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Characterization of an Antagonist Interleukin-6 Dimer by Stable Isotope Labeling, Cross-linking, and Mass Spectrometry
Published in The Journal of biological chemistry (29-11-2002)“…The homodimeric form of a recombinant cytokine interleukin-6 (IL-6 D ) is known to antagonize IL-6 signaling. In this study, spatially proximal residues…”
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Neurotrophic Keratopathy in the United States: An Intelligent Research in Sight Registry Analysis
Published in Ophthalmology (Rochester, Minn.) (01-11-2022)“…To describe the characteristics of neurotrophic keratopathy (NK) in the United States. Retrospective database study. Thirty-one thousand nine hundred fifteen…”
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Abnormal Nuclear Pore Formation Triggers Apoptosis in the Intestinal Epithelium of elys -Deficient Zebrafish
Published in Gastroenterology (New York, N.Y. 1943) (01-03-2009)“…Background & Aims Zebrafish mutants generated by ethylnitrosourea-mutagenesis provide a powerful tool for dissecting the genetic regulation of developmental…”
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The complete mitochondrial genome of the pygmy squid, Idiosepius (Cephalopoda: Decapodiformes): the first representative from the family Idiosepiidae
Published in Mitochondrial DNA. Part A. DNA mapping, sequencing, and analysis (02-01-2016)“…We report the first complete mitochondrial genome of the pygmy squid, Idiosepius, (Idiosepiidae). The mtDNA genome is 16,183 bp long with an AT content of…”
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