Search Results - "Hall, Leroy"

Protective role of spleen-derived macrophages in lung inflammation, injury, and fibrosis induced by nitrogen mustard by Venosa, Alessandro, Malaviya, Rama, Gow, Andrew J, Hall, Leroy, Laskin, Jeffrey D, Laskin, Debra L

“…Nitrogen mustard (NM) is a vesicant that causes lung injury and fibrosis, accompanied by a persistent macrophage inflammatory response. In these studies we…”
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Beyond miR-122: Identification of MicroRNA Alterations in Blood During a Time Course of Hepatobiliary Injury and Biliary Hyperplasia in Rats by Church, Rachel J, Otieno, Monicah, McDuffie, James Eric, Singh, Bhanu, Sonee, Manisha, Hall, LeRoy, Watkins, Paul B, Ellinger-Ziegelbauer, Heidrun, Harrill, Alison H

“…Identification of circulating microRNAs for the diagnosis of liver injury and as an indicator of underlying pathology has been the subject of recent…”
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Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production by Dragomir, Ana-Cristina, Sun, Richard, Mishin, Vladimir, Hall, LeRoy B, Laskin, Jeffrey D, Laskin, Debra L

“…Galectin-3 (Gal-3) is a β-galactoside-binding lectin implicated in the regulation of macrophage activation and inflammatory mediator production. In the present…”
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Repeated exposure of house dust mite induces progressive airway inflammation in mice: Differential roles of CCL17 and IL‐13 by Malaviya, Ravi, Zhou, Zhao, Raymond, Holly, Wertheimer, Josh, Jones, Brian, Bunting, Rachel, Wilkinson, Patrick, Madireddy, Lohith, Hall, LeRoy, Ryan, Mary, Rao, Tadimeti S.

“…We conducted a systematic evaluation of lung inflammation indued by repeated intranasal exposure (for 10 consecutive days) to a human aeroallergen, house dust…”
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Comparative Effects of Carbapenems on Bacterial Load and Host Immune Response in a Klebsiella pneumoniae Murine Pneumonia Model by HILLIARD, Jamese J, MELTON, John L, HALL, Leroy, ABBANAT, Darren, FERNANDEZ, Jeffrey, WARD, Christine K, BUNTING, Rachel A, BARRON, A, SIMON LYNCH, A, FLAMM, Robert K

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice by MALAVIYA, Ravi, ANSELL, Justin, HALL, Leroy, FAHMY, Mila, ARGENTIERI, Rochelle L, OLINI, Gilbert C, PEREIRA, David W, SUR, Runa, CAVENDER, Druie

“…Cytosolic phospholipase A(2) (cPLA(2)) plays a pivotal role in inflammation by catalyzing the release of arachidonic acid, a substrate for lipoxygenase and…”
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Reduced incidence and severity of collagen-induced arthritis in interleukin-12-deficient mice by McIntyre, K W, Shuster, D J, Gillooly, K M, Warrier, R R, Connaughton, S E, Hall, L B, Arp, L H, Gately, M K, Magram, J

“…Collagen-induced arthritis (CIA) is an animal model for rheumatoid arthritis. The disease is elicited by immunization of genetically susceptible DBA/1 mice…”
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Regulation of Nitrogen Mustard-Induced Lung Macrophage Activation by Valproic Acid, a Histone Deacetylase Inhibitor by Venosa, Alessandro, Gow, James G, Hall, LeRoy, Malaviya, Rama, Gow, Andrew J, Laskin, Jeffrey D, Laskin, Debra L

“…Nitrogen mustard (NM)-induced lung injury is associated with an accumulation of proinflammatory/cytotoxic M1 and antiinflammatory/wound repair M2 macrophages,…”
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Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody by Malaviya, Rama, Sunil, Vasanthi R, Venosa, Alessandro, Verissimo, Vivianne L, Cervelli, Jessica A, Vayas, Kinal N, Hall, LeRoy, Laskin, Jeffrey D, Laskin, Debra L

“…Nitrogen mustard (NM) is a bifunctional alkylating agent that causes acute injury to the lung that progresses to fibrosis. This is accompanied by a prominent…”
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Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation by Sunil, Vasanthi R., Vayas, Kinal N., Cervelli, Jessica A., Malaviya, Rama, Hall, LeRoy, Massa, Christopher B., Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.

“…Nitrogen mustard (NM) is a toxic alkylating agent that causes damage to the respiratory tract. Evidence suggests that macrophages and inflammatory mediators…”
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Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor by Malaviya, Rama, Venosa, Alessandro, Hall, LeRoy, Gow, Andrew J., Sinko, Patrick J., Laskin, Jeffrey D., Laskin, Debra L.

“…Nitrogen mustard (NM) is a toxic vesicant known to cause damage to the respiratory tract. Injury is associated with increased expression of inducible nitric…”
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Age-related increases in ozone-induced injury and altered pulmonary mechanics in mice with progressive lung inflammation by Groves, Angela M, Gow, Andrew J, Massa, Christopher B, Hall, LeRoy, Laskin, Jeffrey D, Laskin, Debra L

“…In these studies we determined whether progressive pulmonary inflammation associated with aging in surfactant protein D (Sftpd)-/- mice leads to an exacerbated…”
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The Inhibin B Response to the Testicular Toxicant 1, 3 Dinitrobenzene in Male Rats: Special Issue on Inhibin B Biomarker Research by SONEE, Manisha, BOGDAN, Nancy, HALL, Leroy, BRYANT, Stewart, VINKEN, Petra

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The Inhibin B Response to the Testicular Toxicant 1, 3 Dinitrobenzene in Male Rats by Sonee, Manisha, Bogdan, Nancy, Hall, LeRoy, Bryant, Stewart, Vinken, Petra

“…BACKGROUND This study was conducted as part of an ILSI‐HESI International Life Sciences Institute‐Health & Environmental Sciences Institute consortium effort…”
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Limited additional release of cardiac troponin I and T in isoproterenol-treated beagle dogs with cardiac injury by Feng, Xiao, Taggart, Peter, Hall, LeRoy, Bryant, Stewart, Sansone, Joseph, Kemmerer, Michael, Herlich, Judy, Lord, Peter

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Targeting cytosolic phospholipase A 2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice by Malaviya, Ravi, Ansell, Justin, Hall, LeRoy, Fahmy, Mila, Argentieri, Rochelle L., Olini, Gilbert C., Pereira, David W., Sur, Runa, Cavender, Druie

“…Cytosolic phospholipase A 2 (cPLA 2) plays a pivotal role in inflammation by catalyzing the release of arachidonic acid, a substrate for lipoxygenase and…”
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The non-GLP toleration/dose range finding study: design and methodology used in an early toxicology screening program by Herlich, Judith A, Taggart, Peter, Proctor, Jim, Stahle, Paul, Colis, Rolland, Hall, LeRoy, Pugsley, Michael K

“…A major directive of Pharmaceutical Research and Development (R&D) is to efficiently advance potential new chemical entities (NCEs) from the Discovery…”
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Neuroticism, forgiveness of others, and blood pressure by Hall, Leroy R

“…This study investigated the relationship between personality, other-forgiveness, and health. Specifically, this investigation was of the personality factor of…”
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Interleukin-12-induced adhesion molecule expression in murine liver by Myers, KJ, Eppihimer, MJ, Hall, L, Wolitzky, B

“…Systemically administered interleukin (IL)-12 causes liver inflammation in mice characterized by Kupffer cell proliferation and hypertrophy, hepatocyte…”
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Chronic Toxicity Studies of 5-(2-Pyrazinyl)-4-methyl-l,2-dithiole-3-thione, a Potential Chemopreventive Agent by CROWELL, JAMES A., PAGE, JOHN G., RODMAN, LARRY E., HEATH, JAMES E., GOLDENTHAL, EDWIN I., HALL, LEROY B., KELLOFF, GARY J.

“…The synthetic compound Oltipraz, 5-(2-pyraziny1)-4-methyl-1,2- dithiole-3-thione, is related to the 1,2-dithiolthiones naturally found in cruciferous…”
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