Search Results - "Hall, F. L."
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Prognosis of Patients With Breast Cancer: Causes of Death and Effects of Time Since Diagnosis, Age, and Tumor Characteristics
Published in Journal of clinical oncology (20-10-2011)“…The proportion of women living with a diagnosis of breast cancer in developed countries is increasing. Because breast cancer-specific deaths decrease with time…”
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2
Stimulation of human neutrophils with formyl-methionyl-leucyl- phenylalanine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases
Published in The Journal of immunology (1950) (15-02-1993)“…Stimulation of human polymorphonuclear neutrophils with the chemotactic peptide FMLP induces an increase in the phosphorylation of several proteins on tyrosine…”
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3
CDK2 Encodes a 33-kDa Cyclin A-Associated Protein Kinase and is Expressed Before CDC2 in the Cell Cycle
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1992)“…Critical cell cycle transitions are controlled by the coordinate actions of the p34cdc2protein kinase and its regulatory subunits, cyclins. Recently we…”
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4
WAF1/Cip1 gene polymorphism and expression in carcinomas of the breast, ovary, and endometrium
Published in The American journal of pathology (01-01-1997)“…The p53 gene is altered in approximately 50% of human cancers and is considered to be important in the pathogenesis of these malignancies. The p53 protein…”
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5
FKBP-rapamycin inhibits a cyclin-dependent kinase activity and a cyclin D1-Cdk association in early G1 of an osteosarcoma cell line
Published in The Journal of biological chemistry (25-10-1993)“…Upon entering a cell the natural product rapamycin, like the structurally related immunosuppressant FK506, associates with members of the FKBP family of…”
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6
Phosphorylation and Inactivation of Protein Phosphatase 1 by Cyclin- Dependent Kinases
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-1994)“…Protein phosphatase 1 and protein phosphatase 2A contain potential phosphorylation sites for cyclin-dependent kinases. In the present study we found that…”
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7
Identification of a Novel Proline-directed Serine/Threonine Protein Kinase in Rat Pheochromocytoma
Published in The Journal of biological chemistry (25-09-1989)“…During investigations of the regulation of tyrosine hydroxylase (TH) by protein phosphorylation, a novel protein kinase activity has been discovered in rat…”
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8
Engineering, Expression, and Renaturation of a Collagen-Targeted Human bFGF Fusion Protein
Published in Growth factors (Chur, Switzerland) (2001)“…Abstract Basic fibroblast growth factor (bFGF) is a potent in vitro mitogen for capillary endothelial cells, stimulates angiogenesis in vivo, and may…”
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Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C
Published in The Journal of biological chemistry (25-03-1988)“…The formation of vertebrate neural circuitry is regulated in part by neurotrophic agents, such as nerve growth factor (NGF); however, the biochemical…”
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10
Inhibition of metastatic tumor growth in nude mice by portal vein infusions of matrix-targeted retroviral vectors bearing a cytocidal cyclin G1 construct
Published in Cancer research (Chicago, Ill.) (01-07-2000)“…Tumor invasion and associated angiogenesis evoke a remodeling of extracellular matrix components. Retroviral vectors bearing auxiliary matrix-targeting motifs…”
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11
Detection of a Cdc2-related kinase associated with Alzheimer paired helical filaments
Published in The American journal of pathology (01-01-1995)“…By immunocytochemical staining and Western blotting, we detected a Cdc2-related kinase in human brains. The kinase is recognized by antibodies against the…”
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12
Retroviral vector-mediated gene transfer of antisense cyclin G1 (CYCG1) inhibits proliferation of human osteogenic sarcoma cells
Published in Cancer research (Chicago, Ill.) (01-12-1995)“…Genetic changes found in human osteogenic sarcoma cells, including loss of the p53 and Rb tumor suppressor elements and overexpression of the cyclin G1 (CYCG1)…”
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13
Sequence of simian immunodeficiency virus and its relationship to the human immunodeficiency viruses
Published in Nature (London) (06-08-1987)“…The characterization of HIV-1 (HTLV-III/LAV), the human retrovirus associated with AIDS (acquired immune deficiency syndrome) has led to the identification of…”
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14
Molecular engineering of matrix-targeted retroviral vectors incorporating a surveillance function inherent in von Willebrand factor
Published in Human gene therapy (01-05-2000)“…A major obstacle that limits the potential of human gene therapy is the inefficiency of gene delivery to appropriate sites in vivo. Previous studies…”
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15
Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in mice
Published in Human gene therapy (20-01-2001)“…Targeting cytocidal vectors to tumors and associated vasculature in vivo is a long-standing goal of human gene therapy. In the present study, we demonstrated…”
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16
Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis
Published in Developmental biology (1992)“…A major unsolved problem in developmental biology is to determine when and how time- and position-restricted instructions are signaled and received during…”
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17
Downregulation of cyclin G1 expression by retrovirus-mediated antisense gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation
Published in Circulation (New York, N.Y.) (15-07-1997)“…The contemporary treatment of coronary athero-occlusive disease by percutaneous transluminal coronary angioplasty is hampered by maladaptive wound healing,…”
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18
Inhibition of rabbit keratocyte and human fetal lens epithelial cell proliferation by retrovirus-mediated transfer of antisense cyclin G1 and antisense MAT1 constructs
Published in Human gene therapy (01-01-2000)“…The aim of this study is to evaluate the potential of gene transfer of cell cycle control genes as treatment of corneal haze or secondary cataract formation…”
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Design, expression, and renaturation of a lesion-targeted recombinant epidermal growth factor-von Willebrand factor fusion protein: efficacy in an animal model of experimental colitis
Published in International journal of molecular medicine (01-12-2000)“…In the present study, the mature epidermal growth factor (EGF) protein was engineered to incorporate a high affinity collagen-binding domain (CBD) derived from…”
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Application of synthetic phospho- and unphospho- peptides to identify phosphorylation sites in a subregion of the tau molecule, which is modified in Alzheimer's disease
Published in Journal of neuroscience research (15-02-1993)“…Phospho- and unphospho- peptides were used to define the essential sequence for a tau epitope, which is recognized by Tau-1 antibody and phosphorylated in…”
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