Search Results - "Hall, D. E."

Attenuation of acute mitochondrial dysfunction after traumatic brain injury in mice by NIM811, a non-immunosuppressive cyclosporin A analog by Mbye, L.H., Singh, I.N., Sullivan, P.G., Springer, J.E., Hall, E.D.

“…Following traumatic brain injury (TBI), mitochondrial function becomes compromised. Mitochondrial dysfunction is characterized by intra-mitochondrial Ca2+…”
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Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS by Hall, Edward D., Oostveen, Jo A., Gurney, Mark E.

“…Transgenic mice that highly over‐express a mutated human CuZn superoxide dismutase (SOD1) gene [gly93→ala; TgN(SOD1‐G93A)G1H line] found in some patients with…”
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A comparison of long-term functional outcome after 2 middle cerebral artery occlusion models in rats by ROOF, Robin L, SCHIELKE, Gerald P, XIAODAN REN, HALL, Edward D

“…Proven behavioral assessment strategies for testing potential therapeutic agents in rat stroke models are needed. Few studies include tasks that demand higher…”
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The neuroprotective pharmacology of methylprednisolone by HALL, E. D

“…A 24-hour intensive intravenous dosing regimen with the glucocorticoid steroid methylprednisolone has recently been shown to be effective in enhancing…”
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Estrogen-related gender difference in survival rate and cortical blood flow after impact-acceleration head injury in rats by Roof, R L, Hall, E D

“…While a number of laboratories have begun to examine gender differences in outcome following experimental stroke, little is known about the relative response…”
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A Cell Culture Model of the Blood-Brain Barrier by Rubin, L. L., Hall, D. E., Porter, S., Barbu, K., Cannon, C., Horner, H. C., Janatpour, M., Liaw, C. W., Manning, K., Morales, J., Tanner, L. I., Tomaselli, K. J., Bard, F.

“…Endothelial cells that make up brain capillaries and constitute the blood-brain barrier become different from peripheral endothelial cells in response to…”
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Protein Oxidative Damage in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis by Andrus, Paula K., Fleck, Timothy J., Gurney, Mark E., Hall, Edward D.

“…: The Gly93→Ala mutation in the Cu,Zn superoxide dismutase (Cu,Zn‐SOD) gene (SOD1) found in some familial amyotrophic lateral sclerosis (FALS) patients has…”
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Severe Nutritional Deficiencies in Toddlers Resulting From Health Food Milk Alternatives by Carvalho, Norman F, Kenney, Richard D, Carrington, Paul H, Hall, David E

“…It is widely appreciated that health food beverages are not appropriate for infants. Because of continued growth, children beyond infancy remain susceptible to…”
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Diffusion imaging for evaluation of tumor therapies in preclinical animal models by Moffat, B A, Hall, D E, Stojanovska, J, McConville, P J, Moody, J B, Chenevert, T L, Rehemtulla, A, Ross, B D

“…The increasing development of novel targeted therapies for treating solid tumors has necessitated the development of technology to determine their efficacy in…”
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Inhibition of lipid peroxidation in central nervous system trauma and ischemia by Hall, Edward D.

“…A novel group of compounds, the 21-aminosteroids (“lazaroids”), have been designed that are potent inhibitors of oxygen free radical-induced, iron-catalyzed…”
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Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis by GURNEY, M. E, FLECK, T. J, HIMES, C. S, HALL, E. D

“…Riluzole was tested in a dose-ranging study for preservation of motor function in a transgenic mouse model of familial ALS. The model is based on expression of…”
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Recommended guidelines for studies of human subjects with spinal cord injury by Anderson, D K, Beattie, M, Blesch, A, Bresnahan, J, Bunge, M, Dietrich, D, Dietz, V, Dobkin, B, Fawcett, J, Fehlings, M, Fischer, I, Grossman, R, Guest, J, Hagg, T, Hall, E D, Houle, J, Kleitman, N, McDonald, J, Murray, M, Privat, A, Reier, P, Steeves, J, Steward, O, Tetzlaff, W, Tuszynski, M H, Waxman, S G, Whittemore, S, Wolpaw, J, Young, W, Zheng, B

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Activation of iCaspase-9 in Neovessels Inhibits Oral Tumor Progression by Pinsky, M.S., Song, W., Dong, Z., Warner, K., Zeitlin, B., Karl, E., Hall, D.E., Nör, J.E.

“…Tumors of the oral cavity are highly vascularized malignancies. Disruption of neovascular networks was shown to limit the access of nutrients and oxygen to…”
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Mild pre- and posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat by Smith, S L, Hall, E D

“…Recent studies have demonstrated a neuroprotective effect of mild/moderate hypothermia in models of cerebral trauma and ischemia. In contrast, hypotension is…”
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Preoperative Rehabilitation Is Feasible in the Weeks Prior to Surgery and Significantly Improves Functional Performance by Hall, Daniel E, Youk, A, Allsup, K, Kennedy, K, Byard, T. D, Dhupar, R, Chu, D, Rahman, A. M, Wilson, M, Cahalin, L. P, Afilalo, J, man, D

“…BackgroundFrailty is a multidimensional state of increased vulnerability. Frail patients are at increased risk for poor surgical outcomes. Prior research…”
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Pathophysiology of spinal cord trauma by Anderson, D K, Hall, E D

“…This article reviews the pathophysiology of spinal cord injury. The focus is on the role of post-traumatic membrane lipid changes, including lipid hydrolysis…”
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Lipid antioxidants in acute central nervous system injury by Hall, E D

“…Oxygen radical-mediated lipid peroxidation increasingly has been suggested to be an important factor in post-traumatic neuronal degeneration. Thus, numerous…”
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Effects of the 21-aminosteroid U74006F on posttraumatic spinal cord ischemia in cats by Hall, E D

“…The ability of a single intravenous dose of the 21-aminosteroid U74006F to affect the development of posttraumatic spinal cord ischemia was examined in…”
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Effects of the 21-aminosteroid U74006F on experimental head injury in mice by Hall, E D, Yonkers, P A, McCall, J M, Braughler, J M

“…The ability of a novel non-glucocorticoid 21-aminosteroid U74006F to inhibit lipid peroxidation of central nervous system tissue in vitro and to enhance the…”
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Predicting postfire erosion and mitigation effectiveness with a web-based probabilistic erosion model by Robichaud, P.R., Elliot, W.J., Pierson, F.B., Hall, D.E., Moffet, C.A.

“…The decision of where, when, and how to apply the most effective postfire erosion mitigation treatments requires land managers to assess the risk of damaging…”
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