Search Results - "Hall, Angela M."

Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans by Liss, Kim H.H., Lutkewitte, Andrew J., Pietka, Terri, Finck, Brian N., Franczyk, Michael, Yoshino, Jun, Klein, Samuel, Hall, Angela M.

“…Adipocyte triglyceride storage provides a reservoir of energy that allows the organism to survive times of nutrient scarcity, but excessive adiposity has…”
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Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver by Hall, Angela M., Kou, Kou, Chen, Zhouji, Pietka, Terri A., Kumar, Mrudula, Korenblat, Kevin M., Lee, Kyuha, Ahn, Kay, Fabbrini, Elisa, Klein, Samuel, Goodwin, Bryan, Finck, Brian N.

“…Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic…”
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Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response[S] by Lutkewitte, Andrew J., McCommis, Kyle S., Schweitzer, George G., Chambers, Kari T., Graham, Mark J., Wang, Lingjue, Patti, Gary J., Hall, Angela M., Finck, Brian N.

“…During prolonged fasting, the liver plays a central role in maintaining systemic energy homeostasis by producing glucose and ketones in processes fueled by…”
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Fatty acid metabolism in adipocytes: functional analysis of fatty acid transport proteins 1 and 4 by Lobo, Sandra, Wiczer, Brian M., Smith, Ann J., Hall, Angela M., Bernlohr, David A.

“…The role of fatty acid transport protein 1 (FATP1) and FATP4 in facilitating adipocyte fatty acid metabolism was investigated using stable FATP1 or FATP4…”
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Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation by Mitra, Mayurranjan S., Chen, Zhouji, Ren, Hongmei, Harris, Thurl E., Chambers, Kari T., Hall, Angela M., Nadra, Karim, Klein, Samuel, Chrast, Roman, Su, Xiong, Morris, Andrew J., Finck, Brian N.

“…Lipin 1 is a coregulator of DNA-bound transcription factors and a phosphatidic acid (PA) phosphatase (PAP) enzyme that catalyzes a critical step in the…”
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Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1 by Lutkewitte, Andrew J., Singer, Jason M., Shew, Trevor M., Martino, Michael R., Hall, Angela M., He, Mai, Finck, Brian N.

“…Monoacylglycerol acyltransferase (MGAT) enzymes catalyze the synthesis of diacylglycerol from monoacylglycerol. Previous work has suggested the importance of…”
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CD36-Facilitated Fatty Acid Uptake Inhibits Leptin Production and Signaling in Adipose Tissue by HAJRI, Tahar, HALL, Angela M, JENSEN, Dalan R, PIETKA, Terri A, DROVER, Victor A, HUAN TAO, ECKEL, Robert, ABUMRAD, Nada A

“…CD36-Facilitated Fatty Acid Uptake Inhibits Leptin Production and Signaling in Adipose Tissue Tahar Hajri 1 , Angela M. Hall 2 , Dalan R. Jensen 3 , Terri A…”
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Characterization of the Acyl-CoA Synthetase Activity of Purified Murine Fatty Acid Transport Protein 1 by Hall, Angela M., Smith, Anne J., Bernlohr, David A.

“…Fatty acid transport protein 1 (FATP1) is an ∼63-kDa plasma membrane protein that facilitates the influx of fatty acids into adipocytes as well as skeletal and…”
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Enzymatic Properties of Purified Murine Fatty Acid Transport Protein 4 and Analysis of Acyl-CoA Synthetase Activities in Tissues from FATP4 Null Mice by Hall, Angela M., Wiczer, Brian M., Herrmann, Thomas, Stremmel, Wolfgang, Bernlohr, David A.

“…Fatty acid transport protein 4 (FATP4) is an integral membrane protein expressed in the plasma and internal membranes of the small intestine and adipocyte as…”
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Lipin 2 Is a Liver-enriched Phosphatidate Phosphohydrolase Enzyme That Is Dynamically Regulated by Fasting and Obesity in Mice by Gropler, Matthew C., Harris, Thurl E., Hall, Angela M., Wolins, Nathan E., Gross, Richard W., Han, Xianlin, Chen, Zhouji, Finck, Brian N.

“…Lipin 1 is a bifunctional intracellular protein that regulates fatty acid metabolism in the nucleus via interactions with DNA-bound transcription factors and…”
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Sexually dimorphic effect of aging on skeletal muscle protein synthesis by Smith, Gordon I, Reeds, Dominic N, Hall, Angela M, Chambers, Kari T, Finck, Brian N, Mittendorfer, Bettina

“…Although there appear to be no differences in muscle protein turnover in young and middle aged men and women, we have reported significant differences in the…”
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Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice[S] by Hall, Angela M., Brunt, Elizabeth M., Chen, Zhouji, Viswakarma, Navin, Reddy, Janardan K., Wolins, Nathan E., Finck, Brian N.

“…Lipid droplet proteins (LDPs) coat the surface of triglyceride-rich lipid droplets and regulate their formation and lipolysis. We profiled hepatic LDP…”
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Hepatic Expression of Cell Death-inducing DFFA-like Effector C in Obese Subjects Is Reduced by Marked Weight Loss by Hall, Angela M., Brunt, Elizabeth M., Klein, Samuel, Finck, Brian N.

“…The hepatic expression of the cell death–inducing DNA fragmentation factor A–like effector family (CIDEA, CIDEB, and CIDEC) genes is markedly upregulated in…”
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Mouse fatty acid transport protein 4 (FATP4): Characterization of the gene and functional assessment as a very long chain acyl-CoA synthetase by Herrmann, Thomas, Buchkremer, Florian, Gosch, Isabella, Hall, Angela M, Bernlohr, David A, Stremmel, Wolfgang

“…FATP4 (SLC27A4) is a member of the fatty acid transport protein (FATP) family, a group of evolutionarily conserved proteins that are involved in cellular…”
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Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance? by Finck, Brian N., Hall, Angela M.

“…Numerous studies conducted on obese humans and various rodent models of obesity have identified a correlation between hepatic lipid content and the development…”
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ChREBP refines the hepatic response to fructose to protect the liver from injury by Hall, Angela M, Finck, Brian N

“…Overconsumption of fructose and other sugars has been linked to nonalcoholic fatty liver disease (NAFLD); however, the sugar-associated effects that lead to…”
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FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells by Hatch, Grant M, Smith, Anne J, Xu, Fred Y, Hall, Angela M, Bernlohr, David A

“…Biosynthesis of lipids was investigated in growing 293 cells stably expressing fatty acid (FA) transport protein 1 (FATP1), a bifunctional polypeptide with FA…”
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Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice by Singer, Jason M., Shew, Trevor M., Ferguson, Daniel, Renkemeyer, M. Katie, Pietka, Terri A., Hall, Angela M., Finck, Brian N., Lutkewitte, Andrew J.

“…Objective Monoacylglycerol O‐acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes…”
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Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid by Chen, Yana, McCommis, Kyle S, Ferguson, Daniel, Hall, Angela M, Harris, Charles A, Finck, Brian N

“…Abstract Several recent studies have suggested that compounds known as endocrine-disrupting chemicals (EDCs) can promote obesity by serving as ligands for…”
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Insulin Resistance and Metabolic Derangements in Obese Mice Are Ameliorated by a Novel Peroxisome Proliferator-activated Receptor γ-sparing Thiazolidinedione by Chen, Zhouji, Vigueira, Patrick A., Chambers, Kari T., Hall, Angela M., Mitra, Mayurranjan S., Qi, Nathan, McDonald, William G., Colca, Jerry R., Kletzien, Rolf F., Finck, Brian N.

“…Currently approved thiazolidinediones (TZDs) are effective insulin-sensitizing drugs that may have efficacy for treatment of a variety of metabolic and…”
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