Search Results - "Hall, Adam C."
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Role for Metallothioneins-I/II in Isoflurane Preconditioning of Primary Murine Neuronal Cultures
Published in Anesthesiology (Philadelphia) (01-03-2009)“…Pretreatment with inhaled anesthetics, including isoflurane, can induce long-lasting cellular protection against ischemia-derived toxicity in multiple tissues,…”
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2
Interactions of DEET and Novel Repellents With Mosquito Odorant Receptors
Published in Journal of medical entomology (01-07-2020)“…The carboxamide N, N-di-ethyl-meta-toluamide (DEET) is the most effective and widely used insect repellent today. However, drawbacks concerning the efficacy…”
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3
Microarray Analyses of Genes Regulated by Isoflurane Anesthesia In Vivo: A Novel Approach to Identifying Potential Preconditioning Mechanisms
Published in Anesthesia and analgesia (01-03-2013)“…Although general anesthetics are recognized for their potential to render patients unconscious during surgery, exposure can also lead to long-term outcomes of…”
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4
Alkylphenol inverse agonists of HCN1 gating: H-bond propensity, ring saturation and adduct geometry differentially determine efficacy and potency
Published in Biochemical pharmacology (01-05-2019)“…[Display omitted] In models of neuropathic pain, inhibition of HCN1 is anti-hyperalgesic. 2,6-di-iso-propyl phenol (propofol) and its non-anesthetic congener,…”
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Cation transport by a redox-active synthetic ion channel
Published in Organic & biomolecular chemistry (21-08-2003)“…The synthesis, cation binding and transmembrane conductive properties of a novel group of synthetic ion channels containing a redox-active centre are…”
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Menthol shares general anesthetic activity and sites of action on the GABAA receptor with the intravenous agent, propofol
Published in European journal of pharmacology (20-08-2008)Get full text
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Differential Potency of 2,6-Dimethylcyclohexanol Isomers for Positive Modulation of GABAA Receptor Currents
Published in The Journal of pharmacology and experimental therapeutics (01-06-2016)“…GABAA receptors meet all of the pharmacological requirements necessary to be considered important targets for the action of general anesthetic agents in the…”
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8
Menthol shares general anesthetic activity and sites of action on the GABA A receptor with the intravenous agent, propofol
Published in European journal of pharmacology (20-08-2008)“…Menthol and related compounds were investigated for modulation of recombinant human γ-aminobutyric acid type A (GABA A, α 1β 2γ 2s) receptor currents expressed…”
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9
Modulation of human GABAA and glycine receptor currents by menthol and related monoterpenoids
Published in European journal of pharmacology (03-12-2004)“…Effects of common monoterpenoid alcohols and ketones were investigated on recombinant human gamma-aminobutyric acid A (GABAA; alpha1beta2gamma2s) and glycine…”
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10
Assessment of general anaesthetic cytotoxicity in murine cortical neurones in dissociated culture
Published in Toxicology (Amsterdam) (28-04-2011)“…Abstract General anaesthetics are proposed to cause unconsciousness by modulating neuronal excitability in the mammalian brain through mechanisms that include…”
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Cyclohexanol analogues are positive modulators of GABA A receptor currents and act as general anaesthetics in vivo
Published in European journal of pharmacology (30-09-2011)“…GABA A receptors meet all the pharmacological criteria required to be considered important general anaesthetic targets. In the following study, the modulatory…”
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12
Cyclohexanol analogues are positive modulators of GABAA receptor currents and act as general anaesthetics in vivo
Published in European journal of pharmacology (01-09-2011)Get full text
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13
Synthesis and characterization of a redox-active ion channel supporting cation flux in lipid bilayers
Published in Organic & biomolecular chemistry (01-01-2009)“…The synthesis, cation binding and transmembrane conductive properties of a novel synthetic ion channel containing a redox-active ferrocene unit are described…”
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14
The effects of isoflurane on desensitized wild-type and alpha 1(S270H) gamma-aminobutyric acid type A receptors
Published in Anesthesia and analgesia (01-05-2004)“…gamma-aminobutyric acid type A receptors (GABA(A)-R) mediate synaptic inhibition and meet many pharmacological criteria required of important general…”
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Interactions of N, N‐ diethyl‐ meta ‐toluamide (DEET) and Novel Insect Repellents with Mammalian GABA A and Glycine Receptors
Published in The FASEB journal (01-04-2019)“…Abstract only Mosquito‐borne diseases such as malaria, dengue and yellow fever are responsible for millions of deaths annually. Repellents disrupt interactions…”
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16
Interactions of N, N‐ diethyl‐meta‐toluamide (DEET) and Novel Insect Repellents with Mammalian GABAA and Glycine Receptors
Published in The FASEB journal (01-04-2019)“…Mosquito‐borne diseases such as malaria, dengue and yellow fever are responsible for millions of deaths annually. Repellents disrupt interactions between…”
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17
Subunit-dependent block by isoflurane of wild-type and mutant α1S270H GABAA receptor currents in Xenopus oocytes
Published in Neuroscience letters (15-07-2005)Get full text
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18
The Effects of Isoflurane on Desensitized Wild-Type and α1(S270H) γ-Aminobutyric Acid Type A Receptors
Published in Anesthesia and analgesia (01-05-2004)“…γ-aminobutyric acid type A receptors (GABAA-R) mediate synaptic inhibition and meet many pharmacological criteria required of important general anesthetic…”
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Role of membrane conductances and protein synthesis in subjective day phase advances of the hamster circadian clock by neuropeptide Y
Published in The European journal of neuroscience (01-10-1999)“…Neurons of the mammalian circadian pacemaker in the hypothalamic suprachiasmatic nuclei exhibit a rhythm in firing rate that can be reset by neuropeptide Y. We…”
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Circadian modulation of the ryanodine receptor type 2 in the SCN of rodents
Published in Neuroreport (25-02-1999)“…WE examined the temporal modulation of intracellular calcium release channels in the suprachiasmatic nucleus (SCN). We found a circadian rhythm in [H]ryanodine…”
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