Search Results - "Halim, Sobia Ahsan"

α-Glucosidase Inhibition and Molecular Docking Studies of Natural Brominated Metabolites from Marine Macro Brown Alga Dictyopteris hoytii by Ur Rehman, Najeeb, Rafiq, Kashif, Khan, Ajmal, Ahsan Halim, Sobia, Ali, Liaqat, Al-Saady, Nadiya, Hilal Al-Balushi, Abdullah, Al-Busaidi, Haitham Khamis, Al-Harrasi, Ahmed

“…Bioassay guided isolation of the methanolic extract of marine macro brown alga afforded one new metabolite (ethyl methyl 2-bromobenzene 1,4-dioate, ), one new…”
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Antiproliferative and Carbonic Anhydrase II Inhibitory Potential of Chemical Constituents from Lycium shawii and Aloe vera : Evidence from In Silico Target Fishing and In Vitro Testing by Ur Rehman, Najeeb, Halim, Sobia Ahsan, Khan, Majid, Hussain, Hidayat, Yar Khan, Husain, Khan, Ajmal, Abbas, Ghulam, Rafiq, Kashif, Al-Harrasi, Ahmed

“…Roem. & Schult and resin of (L.) BURM. F. are commonly used in Omani traditional medication against various ailments. Herein, their antiproliferative and…”
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Bio-Potency and Molecular Docking Studies of Isolated Compounds from Grewia optiva J.R. Drumm. ex Burret by Ul Bari, Wasim, Ur Rehman, Najeeb, Khan, Ajmal, Ahsan Halim, Sobia, Yuan, Ye, Blaskovich, Mark A T, Ziora, Zyta M, Zahoor, Muhammad, Naz, Sumaira, Ullah, Riaz, Alotaibi, Amal, Al-Harrasi, Ahmed

“…In the study, two novel compounds along with two new compounds were isolated from . The novel compounds have never been reported in any plant source, whereas…”
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In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors by Halim, Sobia Ahsan, Zaheer-Ul-Haq, Khan, Ajmal, Al-Rawahi, Ahmed, Al-Harrasi, Ahmed

“…Interleukin-2 (IL-2) is involved in the activation and differentiation of T-helper cells. Uncontrolled activated T cells play a key role in the pathophysiology…”
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A highly sensitive β-AKBA-Ag-based fluorescent “turn off” chemosensor for rapid detection of abamectin in tomatoes by Ahmad, Touqeer, Mabood, Fazal, Sarwar, Rizwana, Khan, Ajmal, Halim, Sobia Ahsan, Rehman, Najeeb Ur, Csuk, Rene, Boque, Ricard, Al-Harrasi, Ahmed

“…This study presents the synthesis of a sensitive AKBA-Based fluorescent “Turn off” chemosensor for rapid detection of abamectin residues in tomatoes. Silver…”
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Unraveling the role of cloud computing in health care system and biomedical sciences by Sachdeva, Sonali, Bhatia, Saurabh, Al Harrasi, Ahmed, Shah, Yasir Abbas, Anwer, Md. Khalid, Philip, Anil K., Shah, Syed Faisal Abbas, Khan, Ajmal, Ahsan Halim, Sobia

“…Cloud computing has emerged as a transformative force in healthcare and biomedical sciences, offering scalable, on-demand resources for managing vast amounts…”
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Genome Subtraction and Comparison for the Identification of Novel Drug Targets against Mycobacterium avium subsp. hominissuis by Uddin, Reaz, Siraj, Bushra, Rashid, Muhammad, Khan, Ajmal, Ahsan Halim, Sobia, Al-Harrasi, Ahmed

“…complex (MAC) is a major cause of non-tuberculous pulmonary and disseminated diseases worldwide, inducing bronchiectasis, and affects HIV and immunocompromised…”
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Sources of β-galactosidase and its applications in food industry by Saqib, Shaima, Akram, Attiya, Halim, Sobia Ahsan, Tassaduq, Raazia

“…The enzyme β -galactosidases have been isolated from various sources such as bacteria, fungi, yeast, vegetables, and recombinant sources. This enzyme holds…”
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The 7-Hydroxyflavone attenuates chemotherapy-induced neuropathic pain by targeting inflammatory pathway by Ullah, Rahim, Ali, Gowhar, Rasheed, Abdur, Subhan, Fazal, Khan, Ajmal, Ahsan Halim, Sobia, Al-Harrasi, Ahmed

“…[Display omitted] •The 7-Hydroxyflavone attenuates peripheral and central nociceptive pain.•The 7-Hydroxyflavone ameliorates carrageenan induced paw edema.•The…”
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Exploring biological efficacy of coumarin clubbed thiazolo[3,2–b][1,2,4]triazoles as efficient inhibitors of urease: A biochemical and in silico approach by Khan, Imtiaz, Khan, Ajmal, Ahsan Halim, Sobia, Saeed, Aamer, Mehsud, Saifullah, Csuk, René, Al-Harrasi, Ahmed, Ibrar, Aliya

“…[Display omitted] •New coumarinyl thiazolotriazole hybrids were designed and synthesized.•Various functional groups were tolerated, guiding the initial…”
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In Silico Prediction of Novel Inhibitors of SARS-CoV-2 Main Protease through Structure-Based Virtual Screening and Molecular Dynamic Simulation by Halim, Sobia Ahsan, Waqas, Muhammad, Khan, Ajmal, Al-Harrasi, Ahmed

“…The unprecedented pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is threatening global health. SARS-CoV-2 has caused severe disease…”
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Rational Design of Novel Inhibitors of α-Glucosidase: An Application of Quantitative Structure Activity Relationship and Structure-Based Virtual Screening by Halim, Sobia Ahsan, Jabeen, Sumaira, Khan, Ajmal, Al-Harrasi, Ahmed

“…α-Glucosidase is considered a prime drug target for Diabetes Mellitus and its inhibitors are used to delay carbohydrate digestion for the treatment of diabetes…”
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Recent advances in combinatorial cancer therapy via multifunctionalized gold nanoparticles by Ahmad, Touqeer, Sarwar, Rizwana, Iqbal, Ayesha, Bashir, Uzma, Farooq, Umar, Halim, Sobia Ahsan, Khan, Ajmal, Al-Harrasi, Ahmed

“…The diverse behavior of nanogold in the therapeutic field is related to its unique size and shape. Nanogold offers improvements in modern diagnostic and…”
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Anti-nociceptive and Anti-inflammatory Activities of Asparacosin A Involve Selective Cyclooxygenase 2 and Inflammatory Cytokines Inhibition: An in-vitro, in-vivo , and in-silico Approach by Karim, Nasiara, Khan, Inamullah, Khan, Waheed, Khan, Imran, Khan, Ajmal, Halim, Sobia Ahsan, Khan, Hizbullah, Hussain, Javid, Al-Harrasi, Ahmed

“…Triterpenes possess anti-inflammatory and anti-nociceptive effects. In this study anti-inflammatory activities of Asparacosin A were evaluated' using…”
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Attenuation of nociceptive and paclitaxel-induced neuropathic pain by targeting inflammatory, CGRP and substance P signaling using 3-Hydroxyflavone by Ullah, Rahim, Ali, Gowhar, Subhan, Fazal, Naveed, Muhammad, Khan, Ajmal, Khan, Jawad, Halim, Sobia Ahsan, Ahmad, Nisar, Zakiullah, Al-Harrasi, Ahmed

“…Paclitaxel is an anti-microtubule agent, most widely used chemotherapeutic agent for the treatment of malignant solid tumors. However, it is associated with…”
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Bio-Oriented Synthesis of Novel (S)-Flurbiprofen Clubbed Hydrazone Schiff’s Bases for Diabetic Management: In Vitro and In Silico Studies by Alam, Aftab, Ali, Mumtaz, Rehman, Najeeb Ur, Ullah, Saeed, Halim, Sobia Ahsan, Latif, Abdul, Zainab, Khan, Ajmal, Ullah, Obaid, Ahmad, Shujaat, Al-Harrasi, Ahmed, Ahmad, Manzoor

“…A new series of (S)-flurbiprofen derivatives 4a–4p and 5a–5n were synthesized with different aromatic or aliphatic aldehydes and ketones to produce Schiff’s…”
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Attenuation of spatial memory in 5xFAD mice by targeting cholinesterases, oxidative stress and inflammatory signaling using 2-(hydroxyl-(2-nitrophenyl)methyl)cyclopentanone by Ullah, Rahim, Ali, Gowhar, Subhan, Fazal, Khan, Ajmal, Ahsan Halim, Sobia, Naveed, Muhammad, Kalsoom, Saima, Al-Harrasi, Ahmed

“…[Display omitted] •2-(hydroxyl-(2-nitrophenyl)methyl)cyclopentanone (2NCP) prevent memory impairment in 5xFAD mice.•2NCP reduces neuroinflammation in in-vivo…”
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Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis by Halim, Sobia Ahsan, Waqas, Muhammad, Khan, Ajmal, Ogaly, Hanan A, Othman, Gehan, Al-Harrasi, Ahmed

“…Sinusitis is one of the most common respiratory inflammatory conditions and a significant health issue that affects millions of people worldwide with a global…”
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One pot domino synthesis of new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thiones (THTTs) as anti-inflammatory and antinociceptive candidates: A proof from in-vivo to in-vitro and in-silico mechanistic studies by Raheem, Sumaya, Khan, Rasool, Pan, Xiandao, Ullah, Rahim, Ahsan Halim, Sobia, Khan, Ajmal, Al-Harrasi, Ahmed

“…[Display omitted] •A series of alkyl/aryl/aralkylamines or amino acids appended tetrahydro-2H-1,3,5-thiadiazine-2-thiones (4a-j, 5a-g, 6 and 7) were…”
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Synthesis, in vitro and in silico study of novel 1,3-diphenylurea derived Schiff bases as competitive α-glucosidase inhibitors by Pasha, Anam Rubbab, Ullah, Saeed, Khan, Ajmal, Halim, Sobia Ahsan, Hussain, Javid, Rehman, Tanzila, Talib, Rimsha, Alharthy, Rima D, Kashtoh, Hamdy, Abdellattif, Magda H, Al-Harrasi, Ahmed, Shafiq, Zahid

“…Diabetes mellitus has become a major global health burden because of several related consequences, including heart disease, retinopathy, cataracts, metabolic…”
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