Search Results - "Halfpenny, I."

PP128 Expression profiling of BRCA1 and BRCA2 deficient human tumours and cell-lines using a breast specific platform to identify a biomarker of DNA repair deficiency by Kerr, P, Mulligan, J, Farztdinov, V, McDyer, F, Halfpenny, I, Delaney, T, Couch, F, Quinn, J, Harkin, P, Kennedy, R

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Investigation of killer cell immunoglobulin-like receptor gene diversity V. KIR3DL2 by Meenagh, A., Williams, F., Sleator, C., Halfpenny, I. A., Middleton, D.

“…:  Allelic definition within the killer cell immunoglobulin‐like receptor gene, KIR3DL2, has been achieved through a sequence‐specific oligonucleotide probe…”
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Analysis of KIR gene frequencies in HLA class I characterised bladder, colorectal and laryngeal tumours by Middleton, D., Vilchez, J. R., Cabrera, T., Meenagh, A., Williams, F., Halfpenny, I., Maleno, I., Ruiz-Cabello, F., Lopez-Nevot, M. A., Garrido, F.

“…Three cohorts of patients with laryngeal, bladder or colorectal tumours were investigated for frequency of killer immunoglobulin‐like receptor (KIR) genes…”
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Identification of molecular subtypes within a formalin-fixed, paraffin-embedded breast cancer tumour cohort by Mulligan, JM, McDyer, F, Deharo, S, Farztdinov, V, Halfpenny, I, Delaney, T, Couch, F, Quinn, JE, Harkin, P, Kennedy, R

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Identification of a novel breast cancer molecular subgroup associated with a deficiency in DNA-damage response by Mulligan, J. M., Hill, L. A., Deharo, S., McDyer, F. A., Davison, T. S., Bylesjo, M., Lindor, N. M., Galligan, L., Delaney, T., Halfpenny, I. A., Farztdinov, V., Goffard, N., Proutski, V., Keating, K. E., Mullan, P. B., Quinn, J. E., Johnston, P. G., Couch, F. J., Harkin, D. P., Kennedy, R. D.

“…Abstract only…”
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Predicting response to RAD001 treatment in post-menopausal women with ER-positive breast cancer using the breast cancer DSA™ research tool (Almac) by Sabine, VS, McCulla, A, Wilson, CL, Sims, AH, McDyer, F, McCluskey, C, Halfpenny, I, Oliver, GR, Macaskill, EJ, Renshaw, L, Thomas, JS, Dixon, JM, Bartlett, JM

“…Abstract Abstract #2032 Background: RAD001 (everolimus) is a rapamycin derivative that inhibits mTOR and its downstream substrates and has shown promising…”
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KIR genes by Middleton, Derek, Williams, Fionnuala, Halfpenny, Iris A.

“…This review updates the on-going investigations into KIR genes and their alleles with the main emphasis on what has taken place in this laboratory over the…”
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Investigation of killer cell immunoglobulin-like receptor gene diversity: IV. KIR3DL1/S1 by Halfpenny, Iris A., Middleton, Derek, Barnett, Yvonne A., Williams, Fionnuala

“…The polymorphic nature of the KIR3DL1/S1 gene complex has been investigated through the development of a polymerase chain reaction-sequence-specific…”
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Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals by Williams, Fionnuala, Maxwell, Lynn D, Halfpenny, Iris A, Meenagh, Ashley, Sleator, Carole, Curran, Martin D, Middleton, Derek

“…Multiple copies of the killer immunoglobulin-like receptor gene, 3DL/S1, have been identified in certain individuals. Additionally, allele determination of the…”
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