Search Results - "Hales, Karen G"

Anillin-mediated targeting of peanut to pseudocleavage furrows is regulated by the GTPase Ran by Silverman-Gavrila, Rosalind V, Hales, Karen G, Wilde, Andrew

“…During early development in Drosophila, pseudocleavage furrows in the syncytial embryo prevent contact between neighboring spindles, thereby ensuring proper…”
Get full text

Signaling Inclusivity in Undergraduate Biology Courses through Deliberate Framing of Genetics Topics Relevant to Gender Identity, Disability, and Race by Hales, Karen G

“…The study of genetics centers on how encoded information in DNA underlies similarities and differences between individuals and how traits are inherited…”
Get full text

Genetics on the Fly: A Primer on the Drosophila Model System by Hales, Karen G, Korey, Christopher A, Larracuente, Amanda M, Roberts, David M

“…Fruit flies of the genus Drosophila have been an attractive and effective genetic model organism since Thomas Hunt Morgan and colleagues made seminal…”
Get full text

Iron testes: sperm mitochondria as a context for dissecting iron metabolism by Hales, Karen G

“…A recent paper in BMC Developmental Biology reports that a mitochondrial iron importer is required for Drosophila male fertility and normal mitochondrial…”
Get full text

Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p by Hermann, G.J. (University of Utah, Salt Lake City, UT.), Thatcher, J.W, Mills, J.P, Hales, K.G, Fuller, M.T, Nunnari, J, Shaw, J.M

“…Membrane fusion is required to establish the morphology and cellular distribution of the mitochondrial compartment. In Drosophila, mutations in the fuzzy…”
Get full text

The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster by Miller, Danny E, Cook, Kevin R, Hemenway, Elizabeth A, Fang, Vivienne, Miller, Angela L, Hales, Karen G, Hawley, R Scott

“…Balancer chromosomes are multiply inverted and rearranged chromosomes used in for many tasks, such as maintaining mutant alleles in stock and complex stock…”
Get full text

Developmentally Regulated Mitochondrial Fusion Mediated by a Conserved, Novel, Predicted GTPase by Hales, Karen G, Fuller, Margaret T

“…The Drosophila melanogaster fuzzy onions( fzo) gene encodes the first known protein mediator of mitochondrial fusion. During Drosophila spermatogenesis,…”
Get full text

Asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis by Anderson, Michael A, Jodoin, Jeanne N, Lee, Ethan, Hales, Karen G, Hays, Thomas S, Lee, Laura A

“…Spermatogenesis uses mitotic and meiotic cell cycles coordinated with growth and differentiation programs to generate functional sperm. Our analysis of a…”
Get full text

A chromatin-associated kinesin-related protein required for normal mitotic chromosome segregation in Drosophila by Molina, I. (UAM, Madrid, Spain.), Baars, S, Brill, J.A, Hales, K.G, Fuller, M.T, Ripoll, P

“…The tiovivo (tio) gene of Drosophila encodes a kinesin-related protein, KLP38B, that colocalizes with condensed chromatin during cell division. Wild-type…”
Get full text

The machinery of mitochondrial fusion, division, and distribution, and emerging connections to apoptosis by Hales, Karen G

“…Mitochondrial undergo regulated fusion and division in many organisms and cell types, and each event is mediated by a different complex of proteins each…”
Get full text

A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis by Bergner, Laura M, Hickman, F Edward, Wood, Kathleen H, Wakeman, Carolyn M, Stone, Hunter H, Campbell, Tessa J, Lightcap, Samantha B, Favors, Sheena M, Aldridge, Amanda C, Hales, Karen G

“…Temporal coordination of meiosis with spermatid morphogenesis is crucial for successful generation of mature sperm cells. We identified a recessive male…”
Get more information

Cytokinesis: an emerging unified theory for eukaryotes? by Hales, Karen G, Bi, Erfei, Wu, Jian-Qiu, Adam, Jennifer C, Yu, I-Ching, Pringle, John R

“…In animal and fungal cells, cytokinesis involves an actomyosin ring that forms and contracts at the division plane. Important new details have emerged…”
Get full text

Roles for Drp1, a Dynamin-related Protein, and Milton, a Kinesin-associated Protein, in Mitochondrial Segregation, Unfurling, and Elongation During Drosophila Spermatogenesis by Aldridge, Amanda C., Benson, Levi, Siegenthaler, Monica M., Whigham, Benjamin T., Stowers, R. Steven, Hales, Karen G.

“…Mitochondria undergo dramatic rearrangement during Drosophila spermatogenesis. In wild type testes, the many small mitochondria present in pre-meiotic…”
Get full text

Testis-specific ATP synthase peripheral stalk subunits required for tissue-specific mitochondrial morphogenesis in Drosophila by Sawyer, Eric M, Brunner, Elizabeth C, Hwang, Yihharn, Ivey, Lauren E, Brown, Olivia, Bannon, Megan, Akrobetu, Dennis, Sheaffer, Kelsey E, Morgan, Oshauna, Field, Conroy O, Suresh, Nishita, Gordon, M Grace, Gunnell, E Taylor, Regruto, Lindsay A, Wood, Cricket G, Fuller, Margaret T, Hales, Karen G

“…In Drosophila early post-meiotic spermatids, mitochondria undergo dramatic shaping into the Nebenkern, a spherical body with complex internal structure that…”
Get full text

Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila by Shih, Hsin-Pei, Hales, Karen G, Pringle, John R, Peifer, Mark

“…The septins are a family of proteins involved in cytokinesis and other aspects of cell-cortex organization. In a two-hybrid screen designed to identify…”
Get full text

Denying Genetic Causality by Hales, Karen G.

“…This edited volume of essays presents a countermainstream view against genetic underpinnings for cancer, behavior, and psychiatric conditions…”
Get full text

Letters by Hales, Karen G.

Get full text

Letters by Hales, Karen G.

Get full text

"Finding a Lost Mouse" Refined by Hales, Karen G.

Get full text

Roles for Drp1, a Dynamin-related Protein, and Milton, a Kinesin-associated Protein, in Mitochondrial Segregation, Unfurling, and Elongation During Drosophila Spermatogenesis by Levi Benson, Amanda C. Aldridge, Monica M. Siegenthaler, Karen G. Hales, R. Steven Stowers, Benjamin T. Whigham

“…Mitochondria undergo dramatic rearrangement during Drosophila spermatogenesis. In wild type testes, the many small mitochondria present in pre-meiotic…”
Get full text