Search Results - "Hale, Kari"

Performance of epigenetic markers SEPT9 and ALX4 in plasma for detection of colorectal precancerous lesions by Tänzer, Marc, Balluff, Benjamin, Distler, Jürgen, Hale, Kari, Leodolter, Andreas, Röcken, Christoph, Molnar, Bela, Schmid, Roland, Lofton-Day, Catherine, Schuster, Tibor, Ebert, Matthias P A

“…Screening for colorectal cancer (CRC) has shown to reduce cancer-related mortality, however, acceptance and compliance to current programmes are poor…”
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Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease by Model, Fabian, Osborn, Neal, Ahlquist, David, Gruetzmann, Robert, Molnar, Bela, Sipos, Ferenc, Galamb, Orsolya, Pilarsky, Christian, Saeger, Hans-Detlev, Tulassay, Zsolt, Hale, Kari, Mooney, Suzanne, Lograsso, Joseph, Adorjan, Peter, Lesche, Ralf, Dessauer, Andreas, Kleiber, Joerg, Porstmann, Baerbel, Sledziewski, Andrew, Lofton-Day, Catherine

“…Aberrant DNA methylation occurs early in oncogenesis, is stable, and can be assayed in tissues and body fluids. Therefore, genes with aberrant methylation can…”
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Expression of Trop2 Cell Surface Glycoprotein in Normal and Tumor Tissues: Potential Implications as a Cancer Therapeutic Target by Stepan, Lara P., Trueblood, Esther S., Hale, Kari, Babcook, John, Borges, Luis, Sutherland, Claire L.

“…Trop2 is a cell-surface glycoprotein reported to be overexpressed in various types of adenocarcinomas with minimal expression in normal tissues. Recent…”
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Abstract 2992: Stringent analysis of large-scale siRNA screens identifies a kinase fusion oncogene by Ruefli-Brasse, Astrid A., Hart, Cynthia, Fajardo, Liza, Swearingen, Elissa, Wong, Linda, Sakamoto, Doreen, Hale, Kari, Ge, Huanying, McDowell, Jeffery, Ramachandran, Bharath, Cosgrove, Elissa, Watson, J.E.Vivienne, Ragan, Seamus, Kassner, Paul, Quon, Kim

“…Abstract The interpretation of RNAi knockdown experiments can be challenging due to the extensive off-target effects exhibited by siRNAs and shRNAs. This has…”
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Fetal Hemoglobin Expression Is Differentially Affected by Inhibition of the Proposed Dred Complex Constituents, LSD1 and DNMT1 by Arvedson, Tara L, Tran, Lynn, Ross, Sandra L, Yoder, Sean, Hertz, Alexandra, Hale, Kari, Eschelbach, John, Dineen, Tom, Matyas, Stephanie, Hartley, Cynthia, Morgenstern, Kurt, Winters, Dwight, Cindy, Park, Molineux, Graham, Coxon, Angela

“…Abstract 3263 Sickle cell disease and beta thalassemia are disorders caused by mutations in adult hemoglobin (HbA) or defects in HbA expression. A potential…”
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Expression analyses of CHST4, a carbohydrate sulfotransferase required for L-selectin ligand biosynthesis, suggests novel role in epithelial cells (95.10) by Hopkins, Deborah A, Allred, Sean, Pretorius, James, Harrison, Janine, Hale, Kari, Trueblood, Esther, Ramachandran, Chidambaram

“…Abstract Slowed lymphocyte rolling along high endothelial venules (HEV) is initiated by the L selectin: PNAd interaction, as an essential first step in a…”
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Aristaless-like Homeobox-4 Gene Methylation Is a Potential Marker for Colorectal Adenocarcinomas by Ebert, Matthias P.A., Model, Fabian, Mooney, Suzanne, Hale, Kari, Lograsso, Joe, Tonnes–Priddy, Lori, Hoffmann, Juliane, Csepregi, Antal, Röcken, Christoph, Molnar, Bela, Schulz, Hans–Ulrich, Malfertheiner, Peter, Lofton–Day, Catherine

“…Background & Aims: The identification of novel genetic and epigenetic markers indicative of changes in the pathogenesis of colon cancer, along with…”
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Preparing for your Arrow visit by Hale, Kari

“…The FSA's primary tool for examining a company's High Level Standards (HLS) compliance is the so called "Arrow visit", designed as part of the overarching…”
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Successful governance and regulatory risk management by Hale, Kari

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Using good governance to gain you lighter regulation by Hale, Kari

“…Authorized businesses are facing enormous pressure from an unprecedented amount of complex regulatory obligations and increased external scrutiny on corporate…”
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