Search Results - "Hale, Douglas"

A Cost Comparison for Telehealth Utilization in the Kidney Transplant Waitlist Evaluation Process by Forbes, Rachel C, Rybacki, Diane B, Johnson, Tommy B, Hannah-Gillis, Angela, Shaffer, David, Hale, Douglas A

“…BACKGROUNDThere have been limited publications on telehealth utilization in transplantation with no prior reports of telehealth-related costs for pretransplant…”
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Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (Campath-1H) by KIRK, Allan D, HALE, Douglas A, MANNON, Roslyn B, KLEINER, David E, HOFFMANN, Steven C, KAMPEN, Robert L, CENDALES, Linda K, TADAKI, Douglas K, HARLAN, David M, SWANSON, S. John

“…Profound T-cell depletion before allotransplantation with gradual posttransplant T-cell repopulation induces a state of donor-specific immune…”
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Immunocompetent T‐Cells with a Memory‐Like Phenotype are the Dominant Cell Type Following Antibody‐Mediated T‐Cell Depletion by Pearl, Jonathan P., Parris, Jeremy, Hale, Douglas A., Hoffmann, Steven C., Bernstein, Wendy B., McCoy, Kelly L., Swanson, S. John, Mannon, Roslyn B., Roederer, Mario, Kirk, Allan D.

“…T‐cell depletion facilitates reduced immunosuppression following organ transplantation and has been suggested to be pro‐tolerant. However, the characteristics…”
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Chemokines and Their Receptors in Human Renal Allotransplantation by LO, Denise J, WEAVER, Tim A, KLEINER, David E, MANNON, Roslyn B, JACOBSON, Lynn M, BECKER, Bryan N, SWANSON, S. John, HALE, Douglas A, KIRK, Allan D

“…Chemokines and their receptors play a critical role in leukocyte trafficking, and inhibition of select chemokines has been shown to attenuate kidney disease…”
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Basic transplantation immunology by Hale, Douglas A

“…Humans are protected from a daily onslaught of pathogenic organisms by an immune system that provides multiple layers of protection. Until solid organ…”
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Associations of ABCB1 3435C>T and IL-10 -1082G>A Polymorphisms With Long-Term Sirolimus Dose Requirements in Renal Transplant Patients by SAM, Wai-Johnn, CHAMBERLAIN, Christine E, LEE, Su-Jun, GOLDSTEIN, Joyce A, HALE, Douglas A, MANNON, Roslyn B, KIRK, Allan D, YUEN YI HON

“…Sirolimus (SRL) absorption and metabolism are affected by p-glycoprotein-mediated transport and CYP3A enzyme activity, which are further under the influences…”
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Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin by KIRK, Allan D, MANNON, Roslyn B, HALE, Douglas A, KLEINER, David E, SWANSON, John S, KAMPEN, Robert L, CENDALES, Linda K, ELSTER, Eric A, WAKEFIELD, Terri, CHAMBERLAIN, Christine, HOFFMANN, Steven C

“…Perioperative lymphocyte depletion induces allograft tolerance in some animal models, but in humans has only been shown to reduce immunosuppressive…”
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Functionally Significant Renal Allograft Rejection Is Defined by Transcriptional Criteria by Hoffmann, Steven C., Hale, Douglas A., Kleiner, David E., Mannon, Roslyn B., Kampen, Robert L., Jacobson, Lynn M., Cendales, Linda C., Swanson, S. John, Becker, Bryan N., Kirk, Allan D.

“…Renal allograft acute cellular rejection (ACR) is a T‐cell mediated disease that is diagnosed histologically. However, many normally functioning allografts…”
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Associations of ABCB1 and IL-10 Genetic Polymorphisms With Sirolimus-Induced Dyslipidemia in Renal Transplant Recipients by SAM, Wai-Johnn, CHAMBERLAIN, Christine E, LEE, Su-Jun, GOLDSTEIN, Joyce A, HALE, Douglas A, MANNON, Roslyn B, KIRK, Allan D, HON, Yuen Yi

“…Hyperlipidemia is a common adverse effect of sirolimus (SRL). We previously showed significant associations of ABCB1 3435C>T and IL-10 -1082G>A with…”
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Characteristics Associated With Successful Fitting of a Vaginal Bowel Control System for Fecal Incontinence by Matthews, Catherine A, Varma, Madhulika G, Takase-Sanchez, Michelle M, Hale, Douglas S, Van Drie, Douglas, Muir, Tristi, Wells, Ellen, Jannelli, Mary, Richter, Holly E

“…OBJECTIVESWe previously showed that management with a novel vaginal bowel control system was efficacious in women with moderate to severe fecal incontinence…”
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Obesity following kidney transplantation and steroid avoidance immunosuppression by Elster, Eric A., Leeser, David B., Morrissette, Craig, Pepek, Joseph M., Quiko, Albin, Hale, Douglas A., Chamberlain, Christine, Salaita, Christine, Kirk, Allan D., Mannon, Roslyn B.

“…:  Obesity is an important co‐morbidity within end‐stage renal disease (ESRD) and renal transplant populations. Previous studies have suggested that chronic…”
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IDEC‐131 (Anti‐CD154), Sirolimus and Donor‐Specific Transfusion Facilitate Operational Tolerance in Non‐Human Primates by Preston, Edwin H., Xu, He, Dhanireddy, Kiran K., Pearl, Jonathan P., Leopardi, Frank V., Starost, Matthew F., Hale, Douglas A., Kirk, Allan D.

“…CD154‐specific antibody therapy prevents allograft rejection in many experimental transplant models. However, initial clinical transplant trials with…”
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Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy by Swanson, S John, Hale, Douglas A, Mannon, Roslyn B, Kleiner, David E, Cendales, Linda C, Chamberlain, Christine E, Polly, Shirley M, Harlan, David M, Kirk, Allan D

“…Renal allograft recipients generally need to take several immunosuppressive agents for life. Calcineurin inhibitors and glucocorticosteroids are the mainstays…”
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Biological effects of induction immunosuppression by Hale, Douglas A

“…The concept of induction immunosuppression is evolving. Once used to buttress the inadequacies of past maintenance immunosuppressive regimens, it is now being…”
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Molecular and immunohistochemical characterization of the onset and resolution of human renal allograft ischemia-reperfusion injury by HOFFMANN, Steven C, KAMPEN, Robert L, KIRK, Allan D, AMUR, Shashi, SHARAF, Muhammad A, KLEINER, David E, HUNTER, Keith, SWANSON, S. John, HALE, Douglas A, MANNON, Roslyn B, BLAIR, Patrick J

“…BACKGROUND Following allotransplantation, renal ischemia-reperfusion (I/R) injury initiates a series of events that provokes counter-adaptive immunity. Though…”
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Induction of transplantation tolerance in non-human primate preclinical models by Hale, Douglas A, Dhanireddy, Kiran, Bruno, David, Kirk, Allan D

“…Short-term outcomes following organ transplantation have improved considerably since the availability of cyclosporine ushered in the modern era of…”
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Studies Investigating Pretransplant Donor-Specific Blood Transfusion, Rapamycin, and the CD154-Specific Antibody IDEC-131 in a Nonhuman Primate Model of Skin Allotransplantation by Xu, He, Montgomery, Sean P, Preston, Edwin H, Tadaki, Douglas K, Hale, Douglas A, Harlan, David M, Kirk, Allan D

“…Anti-CD154 variably prolongs allograft survival in nonhuman primates. Rodent studies suggest that adding pretransplant donor-specific transfusion (DST) and/or…”
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Evaluation of tacrolimus abbreviated area-under-the-curve monitoring in renal transplant patients who are potientially at risk for adverse events by Hon, Yuen Yi, Chamberlain, Christine E., Kleiner, David E., Ring, Michael S., Hale, Douglas A., Kirk, Allan D., Mannon, Roslyn B.

“…Hon YY, Chamberlain CE, Kleiner DE, Ring MS, Hale DA, Kirk AD, Mannon RB. Evaluation of tacrolimus abbreviated area‐under‐the‐curve monitoring in renal…”
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IDEC-131 (anti-CD154), sirolimus and donor-specific transfusion facilitate operational tolerance in non-human primates by PRESTON, Edwin H, HE XU, DHANIREDDY, Kiran K, PEARL, Jonathan P, LEOPARDI, Frank V, STAROST, Matthew F, HALE, Douglas A, KIRK, Allan D

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Strategies for minimizing immunosuppression in kidney transplantation by Kirk, Allan D, Mannon, Roslyn B, Swanson, S John, Hale, Douglas A

“…Immunosuppression remains the cause of most morbidity following organ transplantation. However, its use is also responsible for the outstanding graft and…”
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