Search Results - "Halder, Saayak"
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Synthesis and Application of a Versatile Immunoproteasome Activity Probe
Published in Chembiochem : a European journal of chemical biology (04-10-2024)“…The immunoproteasome (iCP) has gained significant interest in recent years as it has been discovered to be significantly expressed under inflammatory…”
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Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity
Published in Proceedings of the National Academy of Sciences - PNAS (23-02-2021)“…The maintenance of sufficient but nontoxic pools of metal micronutrients is accomplished through diverse homeostasis mechanisms in fungi. Siderophores play a…”
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Cytotoxic Oligomers and Fibrils Trapped in a Gel‐like State of α‐Synuclein Assemblies
Published in Angewandte Chemie International Edition (04-05-2018)“…α‐Synuclein (α‐Syn) aggregation is associated with Parkinson's disease (PD) pathogenesis. In PD, the role of oligomers versus fibrils in neuronal cell death is…”
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Solid‐Phase Synthesis and Application of a Clickable Version of Epoxomicin for Proteasome Activity Analysis
Published in Chembiochem : a European journal of chemical biology (05-04-2022)“…Degradation of proteins by the proteasome is an essential cellular process and one that many wish to study in a variety of disease types. There are…”
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Oleic amide derivatives as small molecule stimulators of the human proteasome's core particle
Published in RSC medicinal chemistry (21-09-2022)“…A series of oleic acid amide derivatives were synthesized based on our previous and continuing endeavors towards stimulation of the 20S core particle of the…”
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Synthesis and Application of a Clickable Epoxomicin-Based Probe for Proteasome Activity Analysis
Published in Current protocols (01-07-2022)“…The proteasome is a multisubunit protein complex responsible for the degradation of proteins, making it essential in myriad cellular processes. Several…”
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Cytotoxic Oligomers and Fibrils Trapped in a Gel‐like State of α‐Synuclein Assemblies
Published in Angewandte Chemie (04-05-2018)“…α‐Synuclein (α‐Syn) aggregation is associated with Parkinson's disease (PD) pathogenesis. In PD, the role of oligomers versus fibrils in neuronal cell death is…”
Get full text
Journal Article