Search Results - "Haldar, Subhash"
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Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells
Published in Oncogene (13-02-2020)“…Periodontal diseases can lead to chronic inflammation affecting the integrity of the tooth supporting tissues. Recently, a striking association has been made…”
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Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming
Published in The Journal of clinical investigation (01-10-2018)“…Prostate cancer is an androgen-dependent disease subject to interactions between the tumor epithelium and its microenvironment. Here, we found that epigenetic…”
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Epigenetic changes in fibroblasts drive cancer metabolism and differentiation
Published in Endocrine-related cancer (01-12-2019)“…Genomic changes that drive cancer initiation and progression contribute to the co-evolution of the adjacent stroma. The nature of the stromal reprogramming…”
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Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner
Published in Oncogene (01-01-2019)“…Heterogeneous prostatic carcinoma-associated fibroblasts (CAF) contribute to tumor progression and resistance to androgen signaling deprivation therapy (ADT)…”
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Bone marrow mesenchymal stem cells interact with head and neck squamous cell carcinoma cells to promote cancer progression and drug resistance
Published in Neoplasia (New York, N.Y.) (01-01-2021)“…Head and neck cancers are often diagnosed at later stages with poor outcomes. Mesenchymal stem cells (MSC) are recruited to primary tumor sites where they can…”
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Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Chronic exposure to high glucose inside the human body helps in the progression of cancer by activating various signaling pathways including PI3K, Akt, mTOR,…”
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TGF-β controls stromal telomere length through epigenetic modifications
Published in 3 Biotech (01-11-2022)“…Telomere length is primarily controlled by the enzyme telomerase, but being chromatin structures, telomeres undergo epigenetic regulation for their maintenance…”
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Secondary Structure-Dependent Physicochemical Interaction of Oligonucleotides with Gold Nanorod and Photothermal Effect for Future Applications: A New Insight
Published in ACS omega (31-10-2018)“…We investigate the physicochemical interactions of gold nanorod (GNR) with single-stranded, double-stranded, and hairpin DNA structures to improve the…”
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Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism
Published in Mitochondrion (01-07-2023)“…[Display omitted] •Prostate tumor microenvironment, mtDNA/complement C3a positive feedback paracrine loop is actively involved in cancer-associated stromal…”
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Corrigendum to “Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism” [Mitochondrion 71 (2023) 40-49]
Published in Mitochondrion (01-07-2023)Get full text
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MP20-04 DNA DAMAGE REPAIR GENES REGULATE BLADDER INFLAMMATION
Published in The Journal of urology (01-04-2015)Get full text
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Abstract 2868: Use of methionine metabolites in predicting recurrent prostate cancer affordably
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Abstract Prostate cancer is often an over-treated disease due to our inability to distinguish its indolent & aggressive manifestations. Aggressive prostate…”
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Inflammation and Pyroptosis Mediate Muscle Expansion in an Interleukin-1β (IL-1β)-dependent Manner
Published in The Journal of biological chemistry (06-03-2015)“…Muscle inflammation is often associated with its expansion. Bladder smooth muscle inflammation-induced cell death is accompanied by hyperplasia and hypertrophy…”
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Mechanisms of hemorrhagic cystitis
Published in American journal of clinical and experimental urology (01-01-2014)“…The vast majority of cases of infectious cystitis are easily treated, and most patients have no long-term complications. However, hemorrhagic cystitis is a…”
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Cancer epithelia-derived mitochondrial DNA is a targetable initiator of a paracrine signaling loop that confers taxane resistance
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2020)“…Stromal-epithelial interactions dictate cancer progression and therapeutic response. Prostate cancer (PCa) cells were identified to secrete greater…”
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Antagonizing CD105 enhances radiation sensitivity in prostate cancer
Published in Oncogene (01-08-2018)“…Radiation therapy is the primary intervention for nearly half of the patients with localized advanced prostate cancer and standard of care for recurrent…”
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Parthenolide-Loaded Stimuli-Responsive Cross-Linked Nanocarrier for Targeting and Killing Triple-Negative Breast Cancer Cells
Published in ACS applied nano materials (28-05-2024)“…Aggressive triple-negative breast cancer (TNBC) is a current threat worldwide. The ineffectiveness of current TNBC therapy options highlights the need for…”
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Radiobiological analysis of VMAT treatment plan with flattened and flattening filter free photon beam: an EUD and TCP based comparative study
Published in Reports of practical oncology and radiotherapy (01-01-2024)“…This study aimed to evaluate the dosimetric and radiobiological differences between 6MV flattened filter (FF) and flattening filter free (FFF) using volumetric…”
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Histone deacetylase inhibitors mediate DNA damage repair in ameliorating hemorrhagic cystitis
Published in Scientific reports (20-12-2016)“…Hemorrhagic cystitis is an inflammatory and ulcerative bladder condition associated with systemic chemotherapeutics, like cyclophosphomide. Earlier, we…”
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