Search Results - "Halassy, Beata"

Multi-Detection Size Exclusion Chromatography as an Advanced Tool for Monitoring Enzyme-Antibody Conjugation Reaction and Quality Control of a Final Product by Štimac, Adela, Kurtović, Tihana, Halassy, Beata

“…The multi-detection size exclusion chromatography (SEC) has been recognized as an advanced analytical technique for the characterization of macromolecules and…”
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Development of Improved High-Performance Liquid Chromatography Method for the Determination of Residual Caprylic Acid in Formulations of Human Immunoglobulins by Štimac, Adela, Kurtović, Tihana, Pavlović, Nediljko, Halassy, Beata

“…Quality control of human immunoglobulin formulations produced by caprylic acid precipitation necessitates a simple, rapid, and accurate method for…”
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Recovery of infective virus particles in ion-exchange and hydrophobic interaction monolith chromatography is influenced by particle charge and total-to-infective particle ratio by Sviben, Dora, Forcic, Dubravko, Ivancic-Jelecki, Jelena, Halassy, Beata, Brgles, Marija

“…•Purification recovery of MeV and MuV by IEX is below 20%.•Recovery of MuV and MeV by HIC is around 60%.•MuV and MeV chromatography requires large channel…”
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Snake Antivenoms-Toward Better Understanding of the Administration Route by Gamulin, Erika, Mateljak Lukačević, Sanja, Halassy, Beata, Kurtović, Tihana

“…Envenomations induced by animal bites and stings constitute a significant public health burden. Even though a standardized protocol does not exist,…”
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Roughness of Production Conditions: Does It Really Affect Stability of IgG-Based Antivenoms? by Mateljak Lukačević, Sanja, Kurtović, Tihana, Borić, Juraj, Halassy, Beata

“…Antivenoms contain either pure animal IgGs or their fragments as an active substance, and are the only specific therapeutics against envenomation arising from…”
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Production- and Purification-Relevant Properties of Human and Murine Cytomegalovirus by Ravlić, Sanda, Brgles, Marija, Hiršl, Lea, Jonjić, Stipan, Halassy, Beata

“…There is a large unmet need for a prophylactic vaccine against human cytomegalovirus (HCMV) to combat the ubiquitous infection that is ongoing with this…”
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Refinement strategy for antivenom preparation of high yield and quality by Kurtović, Tihana, Lang Balija, Maja, Brgles, Marija, Sviben, Dora, Tunjić, Monika, Cajner, Hrvoje, Marchetti-Deschmann, Martina, Allmaier, Günter, Halassy, Beata

“…Antivenoms from hyperimmune animal plasma are the only specific pharmaceuticals against snakebites. The improvement of downstream processing strategies is of…”
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Comparison of Preclinical Properties of Several Available Antivenoms in the Search for Effective Treatment of Vipera ammodytes and Vipera berus Envenoming by Kurtović, Tihana, Lang Balija, Maja, Brvar, Miran, Dobaja Borak, Mojca, Mateljak Lukačević, Sanja, Halassy, Beata

“…Snakebites are a relatively rare medical emergency in Europe. In more than half of the annual cases caused by , , and , immunotherapy with animal-derived…”
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Efficient and Sustainable Platform for Preparation of a High-Quality Immunoglobulin G as an Urgent Treatment Option During Emerging Virus Outbreaks by Kurtović, Tihana, Ravlić, Sanda, Štimac, Adela, Mateljak Lukačević, Sanja, Hećimović, Ana, Kazazić, Saša, Halassy, Beata

“…During the pre-vaccine era of the COVID-19 pandemic convalescent plasma has once again emerged as a major potential therapeutic form of passive immunization…”
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Stability, biophysical properties and effect of ultracentrifugation and diafiltration on measles virus and mumps virus by Sviben, Dora, Forčić, Dubravko, Kurtović, Tihana, Halassy, Beata, Brgles, Marija

“…Measles virus and mumps virus (MeV and MuV) are enveloped RNA viruses used for production of live attenuated vaccines for prophylaxis of measles and mumps…”
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What can neutralizing antibodies tell us about the quality of immunity in COVID-19 convalescents and vaccinees? by Ravlić, Sanda, Kurtović, Tihana, Cvetko Krajinović, Lidija, Hećimović, Ana, Miloš, Marija, Mateljak Lukačević, Sanja, Markotić, Alemka, Halassy, Beata

“…During the SARS-CoV-2 pandemic, the lack of standardized measurements of the immune response after vaccination or recovery from COVID-19 resulted in…”
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Biological Activities and Proteomic Profile of the Venom of Vipera ursinii ssp., a very Rare Karst Viper from Croatia by Lang Balija, Maja, Leonardi, Adrijana, Brgles, Marija, Sviben, Dora, Kurtović, Tihana, Halassy, Beata, Križaj, Igor

“…The karst viper ( ssp.) favours high-mountain dry grasslands in southern and south-eastern Croatia. It is medically less important than other species, because…”
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Intravenous Vipera berus Venom-Specific Fab Fragments and Intramuscular Vipera ammodytes Venom-Specific F(ab') 2 Fragments in Vipera ammodytes -Envenomed Patients by Kurtović, Tihana, Karabuva, Svjetlana, Grenc, Damjan, Dobaja Borak, Mojca, Križaj, Igor, Lukšić, Boris, Halassy, Beata, Brvar, Miran

“…( ) is the most venomous European viper. The aim of this study was to compare the clinical efficacy and pharmacokinetic values of intravenous venom-specific…”
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Mass spectrometry-based investigation of measles and mumps virus proteome by Sviben, Dora, Forcic, Dubravko, Halassy, Beata, Allmaier, Günter, Marchetti-Deschmann, Martina, Brgles, Marija

“…Measles (MEV) and mumps virus (MUV) are enveloped, non-segmented, negative single stranded RNA viruses of the family Paramyxoviridae, and are the cause of…”
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An Unconventional Case Study of Neoadjuvant Oncolytic Virotherapy for Recurrent Breast Cancer by Forčić, Dubravko, Mršić, Karmen, Perić-Balja, Melita, Kurtović, Tihana, Ramić, Snježana, Silovski, Tajana, Pedišić, Ivo, Milas, Ivan, Halassy, Beata

“…Intratumoural oncolytic virotherapy may have promise as a means to debulk and downstage inoperable tumours in preparation for successful surgery. Here, we…”
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Quality-Related Properties of Equine Immunoglobulins Purified by Different Approaches by Mateljak Lukačević, Sanja, Kurtović, Tihana, Lang Balija, Maja, Brgles, Marija, Steinberger, Stephanie, Marchetti-Deschmann, Martina, Halassy, Beata

“…Whole IgG antivenoms are prepared from hyperimmune animal plasma by various refinement strategies. The ones most commonly used at industrial scale are…”
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Is Better Standardization of Therapeutic Antibody Quality in Emerging Diseases Epidemics Possible? by Ravlić, Sanda, Hećimović, Ana, Kurtović, Tihana, Ivančić Jelečki, Jelena, Forčić, Dubravko, Slović, Anamarija, Kurolt, Ivan Christian, Mačak Šafranko, Željka, Mušlin, Tatjana, Rnjak, Dina, Jakšić, Ozren, Sorić, Ena, Džepina, Gorana, Đaković Rode, Oktavija, Kujavec Šljivac, Kristina, Vuk, Tomislav, Jukić, Irena, Markotić, Alemka, Halassy, Beata

“…During the ongoing COVID-19 epidemic many efforts have gone into the investigation of the SARS-CoV-2-specific antibodies as possible therapeutics. Currently,…”
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Streamlined downstream process for efficient and sustainable (Fab') 2 antivenom preparation by Kurtović, Tihana, Brgles, Marija, Balija, Maja Lang, Steinberger, Stephanie, Sviben, Dora, Marchetti-Deschmann, Martina, Halassy, Beata

“…Antivenoms are the only validated treatment against snakebite envenoming. Numerous drawbacks pertaining to their availability, safety and efficacy are becoming…”
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A Single Dose of ViperfavTM May Be Inadequate for Vipera ammodytes Snake Bite: A Case Report and Pharmacokinetic Evaluation by Kurtović, Tihana, Brvar, Miran, Grenc, Damjan, Lang Balija, Maja, Križaj, Igor, Halassy, Beata

“…Viperfav TM is a commercial F(ab’) 2 antivenom prepared against European vipers venom. It is safe and effective for treating envenomation caused by Vipera…”
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Adjuvant activity of peptidoglycan monomer and its metabolic products by Halassy, Beata, Krstanović, Marina, Frkanec, Ruža, Tomašić, Jelka

“…Peptidoglycan monomer (PGM) is a natural compound of bacterial origin. It is a non-toxic, non-pyrogenic, water-soluble immunostimulator potentiating humoral…”
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