Search Results - "Halabi, A"

Photoregulated fluxional fluorophores for live-cell super-resolution microscopy with no apparent photobleaching by Halabi, Elias A., Pinotsi, Dorothea, Rivera-Fuentes, Pablo

“…Photoswitchable molecules have multiple applications in the physical and life sciences because their properties can be modulated with light. Fluxional…”
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Effect of renal impairment on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor linagliptin by Graefe-Mody, U., Friedrich, C., Port, A., Ring, A., Retlich, S., Heise, T., Halabi, A., Woerle, H.-J.

“…Aim: This study assessed the influence of various degrees of renal impairment on the exposure of linagliptin, a dipeptidyl peptidase‐4 (DPP‐4) inhibitor with a…”
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Pharmacokinetics, pharmacodynamics and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in subjects with renal impairment by Macha, S., Mattheus, M., Halabi, A., Pinnetti, S., Woerle, H. J., Broedl, U. C.

“…Aims Empagliflozin is a selective sodium glucose cotransporter 2 (SGLT2) inhibitor that inhibits renal glucose reabsorption and is being investigated for the…”
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Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti‐Tumor Immunity in Murine Glioblastoma by Lugani, Sophie, Halabi, Elias A., Oh, Juhyun, Kohler, Rainer H., Peterson, Hannah M., Breakefield, Xandra O., Chiocca, E. Antonio A., Miller, Miles A., Garris, Christopher S., Weissleder, Ralph

“…Myeloid cells are abundant, create a highly immunosuppressive environment in glioblastoma (GBM), and thus contribute to poor immunotherapy responses. Based on…”
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Multiple-dose tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P1 receptor modulator: Favorable impact of dose up-titration by Brossard, P., Scherz, M., Halabi, A., Maatouk, H., Krause, A., Dingemanse, J.

“…This multiple‐ascending‐dose study investigated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ponesimod, an S1P1 receptor modulator and a…”
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Tailings Dam Failures: A Historical Analysis of the Risk by Halabi, A. L. M., Siacara, A. T., Sakano, V. K., Pileggi, R. G., Futai, M. M.

“…The number of great magnitude tailings dam collapses has made society increasingly aware of the need to better understand the risk associated with tailings…”
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Hydrogen adsorption and diffusion on amorphous solid water ice by Al-Halabi, A., Van Dishoeck, E. F.

“…Results of classical trajectory calculations on the adsorption of H atoms to amorphous solid water (ASW) ice, at a surface temperature Ts of 10 K are…”
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Dual-Activatable Cell Tracker for Controlled and Prolonged Single-Cell Labeling by Halabi, Elias A, Arasa, Jorge, Püntener, Salome, Collado-Diaz, Victor, Halin, Cornelia, Rivera-Fuentes, Pablo

“…Cell trackers are fluorescent chemical tools that facilitate imaging and tracking cells within live organisms. Despite their versatility, these dyes lack…”
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In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy by Ko, Jina, Lucas, Kilean, Kohler, Rainer, Halabi, Elias A., Wilkovitsch, Martin, Carlson, Jonathan C. T., Weissleder, Ralph

“…The ability to observe cells in live organisms is essential for understanding their function in complex in vivo milieus. A major challenge today has been the…”
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Reactive scattering of H2 from Cu(100): comparison of dynamics calculations based on the specific reaction parameter approach to density functional theory with experiment by Sementa, L, Wijzenbroek, M, van Kolck, B J, Somers, M F, Al-Halabi, A, Busnengo, H F, Olsen, R A, Kroes, G J, Rutkowski, M, Thewes, C, Kleimeier, N F, Zacharias, H

“…We present new experimental and theoretical results for reactive scattering of dihydrogen from Cu(100). In the new experiments, the associative desorption of…”
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Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery by Das, Riddha, Halabi, Elias A., Fredrich, Ina R., Oh, Juhyun, Peterson, Hannah M., Ge, Xinying, Scott, Ella, Kohler, Rainer H., Garris, Christopher S., Weissleder, Ralph

“…The efficient activation of professional antigen‐presenting cells—such as dendritic cells (DC)—in tumors and lymph nodes is critical for the design of…”
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Pharmacological Polarization of Tumor‐Associated Macrophages Toward a CXCL9 Antitumor Phenotype by Enbergs, Noah, Halabi, Elias A., Goubet, Anne‐Gaëlle, Schleyer, Kelton, Fredrich, Ina R., Kohler, Rainer H., Garris, Christopher S., Pittet, Mikaël J., Weissleder, Ralph

“…Tumor‐associated macrophages (TAM) are a diverse population of myeloid cells that are often abundant and immunosuppressive in human cancers. CXCL9Hi TAM has…”
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Perfusion Window Chambers Enable Interventional Analyses of Tumor Microenvironments by Korolj, Anastasia, Kohler, Rainer H., Scott, Ella, Halabi, Elias A., Lucas, Kilean, Carlson, Jonathan C.T., Weissleder, Ralph

“…Intravital microscopy (IVM) allows spatial and temporal imaging of different cell types in intact live tissue microenvironments. IVM has played a critical role…”
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Effect of Rifampicin on The Pharmacokinetics of Selexipag, An Oral Prostacyclin Receptor Agonist, and Its Active Metabolite In Healthy Male Subjects by Bruderer, S, Petersen-Sylla, M, Boehler, M, Remeňová, T, Halabi, A, Dingemanse, J

“…Methods This was an open-label, randomized, two-treatment, two-period, crossover study including 20 healthy male subjects. Concomitant administration of…”
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Effect of Gemfibrozil on The Pharmacokinetics of Selexipag, An oral Prostacyclin Receptor Agonist, And Its Active Metabolite In Healthy Male Subjects by Bruderer, S, Petersen-Sylla, M, Boehler, M, Remeňová, T, Halabi, A, Dingemanse, J

“…Methods This was an open-label, randomized, two-treatment, two-period, crossover study including 20 healthy male subjects. In the presence of multiple-dose…”
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Synthesis of Dicyano-Substituted Benzo[c]fluorenes from Tetraaryl[3]cumulenes by Gawel, Przemyslaw, Halabi, Elias A., Schweinfurth, David, Trapp, Nils, Ruhlmann, Laurent, Boudon, Corinne, Diederich, François

“…We have developed a one‐step synthesis of 5,6‐dicyano‐7‐(diphenylvinyl)‐7H‐benzo[c]fluorenes, starting from easily accessible tetraaryl[3]cumulenes and…”
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Light-Deactivated Fluorescent Probes (FLASH-Off) for Multiplexed Imaging by Halabi, Elias A., Weissleder, Ralph

“…Highly multiplexed, cyclic fluorescence imaging has advanced our understanding of the biology, evolution, and complexity of human diseases. Currently available…”
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Infantile Parotid Hemangioma With Diagnostic Dilemma: A Case Report by Abidi, Kamel T, Kamal, Naglaa M, Althobaiti, Khaled A, Althobaiti, Sami D, Halabi, Yasser A, Alalyani, Saad A

“…Introduction: Salivary gland tumors are uncommon in children; hemangiomas are one of them. We report a case of infantile hemangioma of the parotid gland which…”
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The effect of mild and moderate renal impairment on the pharmacokinetics of pridopidine, a new drug for Huntington's disease by Rabinovich‐Guilatt, L., Siegler, K. E., Schultz, A., Halabi, A., Rembratt, A., Spiegelstein, O.

“…Aim Pridopidine, a new oral drug for treatment of patients with motor symptoms associated with Huntington's Disease (HD) is currently under development. In…”
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A Photoactivatable Probe for Super-Resolution Imaging of Enzymatic Activity in Live Cells by Halabi, Elias A, Thiel, Zacharias, Trapp, Nils, Pinotsi, Dorothea, Rivera-Fuentes, Pablo

“…A dual-activatable, fluorogenic probe was developed to sense esterase activity with single-molecule resolution. Without enzymatic pre-activation, the…”
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