Search Results - "Halász, M"
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Spatial Stochastic Model of the Pre-B Cell Receptor
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-01-2023)“…Survival and proliferation of immature B lymphocytes requires expression and tonic signaling of the pre-B cell receptor (pre-BCR). This low level,…”
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Modeling the Cluster Size Distribution of Vascular Endothelial Growth Factor (VEGF) Receptors
Published in Bioinformatics and biology insights (01-03-2022)“…We previously developed a method of defining receptor clusters in the membrane based on mutual distance and applied it to a set of transmission microscopy…”
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Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling
Published in Biophysical journal (17-09-2013)“…ErbB1 overexpression is strongly linked to carcinogenesis, motivating better understanding of erbB1 dimerization and activation. Recent…”
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The impact of high density receptor clusters on VEGF signaling
Published in Electronic proceedings in theoretical computer science (27-08-2013)“…Vascular endothelial growth factor (VEGF) signaling is involved in the process of blood vessel development and maintenance. Signaling is initiated by binding…”
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Analytical Solution of Steady-State Equations for Chemical Reaction Networks with Bilinear Rate Laws
Published in IEEE/ACM transactions on computational biology and bioinformatics (01-07-2013)“…True steady states are a rare occurrence in living organisms, yet their knowledge is essential for quasi-steady-state approximations, multistability analysis,…”
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Effect of Spatial Inhomogeneities on the Membrane Surface on Receptor Dimerization and Signal Initiation
Published in Frontiers in cell and developmental biology (12-08-2016)“…Important signal transduction pathways originate on the plasma membrane, where microdomains may transiently entrap diffusing receptors. This results in a…”
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Exploring the Dynamics of Mass Action Systems
Published in Electronic proceedings in theoretical computer science (27-08-2013)“…We present the Populus toolkit for exploring the dynamics of mass action systems under different assumptions…”
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Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells
Published in The Journal of clinical investigation (01-03-2011)“…HSCs either self-renew or differentiate to give rise to multipotent cells whose progeny provide blood cell precursors. However, surprisingly little is known…”
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Use of Stereotactic Radiosurgery for Brain Metastases From Non-Small Cell Lung Cancer in the United States
Published in International journal of radiation oncology, biology, physics (01-02-2013)“…Purpose The indications for treatment of brain metastases from non-small cell lung cancer (NSCLC) with stereotactic radiosurgery (SRS) remain controversial. We…”
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Intensity modulated radiation therapy following lumpectomy in early-stage breast cancer: Patterns of use and cost consequences among Medicare beneficiaries
Published in PloS one (30-09-2019)“…In 2013, the American Society for Radiation Oncology (ASTRO) issued a Choosing Wisely recommendation against the routine use of intensity modulated…”
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Simulation-based learning for enhanced gynecologic brachytherapy training among radiation oncology residents
Published in Brachytherapy (01-01-2021)“…Brachytherapy is an irreplaceable component of gynecologic cancer treatment. Resident training has declined, and procedural exposure is variable. We evaluated…”
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Intracranial Solitary Fibrous Tumor/Hemangiopericytoma Treated with Microsurgical Resection: Retrospective Cohort Analysis of a Single-Center Experience
Published in Therapeutics and clinical risk management (30-09-2022)“…Objective: To provide benchmarks for further studies of solitary fibrous tumor/hemangiopericytoma (SFT/HPC) of the central nervous system (CNS), we…”
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Clinical Outcomes in Patients with Recurrent Glioblastoma Treated with Proton Beam Therapy Reirradiation: Analysis of the Multi-Institutional Proton Collaborative Group Registry
Published in Advances in radiation oncology (01-09-2020)“…As a means of limiting normal tissue toxicity, proton-beam therapy (PBT) is an emerging radiation modality for glioblastoma (GBM) reirradiation. However, data…”
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Impact of fresh fuel loading management in fuel cycle simulators: A functionality isolation test
Published in Nuclear engineering and design (01-06-2022)“…•International effort involving many fuel cycle simulators.•Innovative approach to deal with fuel cycle simulation uncertainties.•Impact on plutonium inventory…”
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Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells
Published in Oncogenesis (New York, NY) (09-10-2017)“…Triple negative breast cancer (TNBC) is an aggressive subtype with relatively poor clinical outcomes and limited treatment options. Chemotherapy, while killing…”
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Physical model of the nuclear fuel cycle simulation code SITON
Published in Annals of nuclear energy (01-01-2017)“…Finding answers to main challenges of nuclear energy, like resource utilisation or waste minimisation, calls for transient fuel cycle modelling. This…”
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The Advantage of Proton Therapy in Hypothalamic-Pituitary Axis and Hippocampus Avoidance for Children with Medulloblastoma
Published in International journal of particle therapy (2022)“…Craniospinal irradiation (CSI) improves clinical outcomes at the cost of long-term neuroendocrine and cognitive sequelae. The purpose of this pilot study was…”
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Skyrmion–anti-Skyrmion annihilation with ω mesons
Published in Physical review. D, Particles and fields (2001)Get full text
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Orchestration of ErbB3 signaling through heterointeractions and homointeractions
Published in Molecular biology of the cell (05-11-2015)“…Members of the ErbB family of receptor tyrosine kinases are capable of both homointeractions and heterointeractions. Because each receptor has a unique set of…”
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