Search Results - "Hakozaki, Tomohiro"

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  1. 1

    Identification of Yellow Advanced Glycation End Products in Human Skin by Fang, Bin, Li, Lijuan, Winget, Jason, Laughlin, Timothy, Hakozaki, Tomohiro

    “…Skin yellowness is a hallmark of dull or unhealthy skin, particularly among Asians. Previous research has indicated a link between skin glycation and skin…”
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    Journal Article
  2. 2

    A framework to mitigate the risk of chemical leukoderma: Consumer products by Bjerke, Donald L., Wu, Shengde, Wakamatsu, Kazumasa, Ito, Shosuke, Wang, Jiazhen, Laughlin, Timothy, Hakozaki, Tomohiro

    Published in Regulatory toxicology and pharmacology (01-06-2022)
    “…Chemical leukoderma is an acquired depigmentation of the skin caused by repeated exposure to specific agents damaging to epidermal melanocytes. Case reports of…”
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  3. 3

    A Potential Role of Keratinocyte-Derived Bilirubin in Human Skin Yellowness and Its Amelioration by Sucrose Laurate/Dilaurate by Fang, Bin, Card, Patrick D, Chen, Junjun, Li, Lijuan, Laughlin, Timothy, Jarrold, Bradley, Zhao, Wenzhu, Benham, Adam M, Määttä, Arto T, Hawkins, Timothy J, Hakozaki, Tomohiro

    “…Sallow and/or dull skin appearance is greatly attributable to the yellow components of skin tone. Bilirubin is a yellow chromophore known to be made in the…”
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    Journal Article
  4. 4

    Unripe peach (Prunus persica) extract ameliorates damage from UV irradiation and improved collagen XVIII expression in 3D skin model by Yonezawa, Tomoko, Momota, Ryusuke, Iwano, Hideki, Zhao, Steven, Hakozaki, Tomohiro, Soh, Chieko, Sawaki, Shigetoyo, Toyama, Kazumi, Oohashi, Toshitaka

    Published in Journal of cosmetic dermatology (01-10-2019)
    “…Summary Introduction Collagen type XVIII regulates cellular activities of adjacent cells at the dermal‐epidermal junction (DEJ). To investigate its possible…”
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  5. 5

    Epidermal Keratinocytes from Light vs. Dark Skin Exhibit Differential Degradation of Melanosomes by Ebanks, Jody P., Koshoffer, Amy, Wickett, R. Randall, Schwemberger, Sandy, Babcock, George, Hakozaki, Tomohiro, Boissy, Raymond E.

    Published in Journal of investigative dermatology (01-06-2011)
    “…Modification of skin complexion coloration has traditionally been accomplished by interruption or attenuation of melanogenesis and/or melanosome transfer…”
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  6. 6

    Hydrolytic enzymes of the interfollicular epidermis differ in expression and correlate with the phenotypic difference observed between light and dark skin by Ebanks, Jody P., Koshoffer, Amy, Wickett, R. Randall, Hakozaki, Tomohiro, Boissy, Raymond E.

    Published in Journal of dermatology (01-01-2013)
    “…Degradation of melanosomes in light skin (LS, i.e. phototype I/II) appears to occur more rapidly than dark skin (DS, i.e. phototype IV/V). Hydrolytic enzymes…”
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  7. 7

    Visualization and characterization of UVB-induced reactive oxygen species in a human skin equivalent model by Hakozaki, Tomohiro, Date, Akira, Yoshii, Takashi, Toyokuni, Shinya, Yasui, Hiroyuki, Sakurai, Hiromu

    Published in Archives of Dermatological Research (01-04-2008)
    “…Reactive oxygen species (ROS) play important roles in the process of ultraviolet-induced skin damage or photoaging. Although many enzymatic and chemical…”
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  8. 8

    Effective inhibition of melanosome transfer to keratinocytes by lectins and niacinamide is reversible by Greatens, Amanda, Hakozaki, Tomohiro, Koshoffer, Amy, Epstein, Howard, Schwemberger, Sandy, Babcock, George, Bissett, Donald, Takiwaki, Hirotsugu, Arase, Seiji, Wickett, R. Randall, Boissy, Raymond E.

    Published in Experimental dermatology (01-07-2005)
    “…:  Skin pigmentation results in part from the transfer of melanized melanosomes synthesized by melanocytes to neighboring keratinocytes. Plasma membrane…”
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  9. 9
  10. 10

    Inhibition of inflammatory nitric oxide production and epidermis damages by Saccharomycopsis Ferment Filtrate by Tsai, Hsiou-Hsin, Chen, Yen-Chou, Lee, Woan-Ruoh, Hu, Chung-Hong, Hakozaki, Tomohiro, Yoshii, Takashi, Shen, Shing-Chuan

    Published in Journal of dermatological science (01-06-2006)
    “…Yeast extracts have been shown to perform anti-inflammatory and cytoprotective activities. However, the effects of yeast extracts on lipopolysaccharide…”
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  11. 11

    Skin inflammatory signatures, as measured by disordered spatial redness patterns, predict current and future skin ageing attributes by Omotezako, Tatsuya, Zhao, Wenzhu, Rodrigues, MyriamRubecca, Ehrman, Matthew, Deng, Denny, Lau, HiuFung, Hakozaki, Tomohiro

    Published in Experimental dermatology (01-08-2024)
    “…Facial skin redness can be an indicator of skin inflammation, however the physiological connection between facial redness and inflammatory status, as well as…”
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  12. 12

    Comprehensive metabolic profiling of Geotrichum candidum and comparison with Saccharomyces cerevisiae by Bamba, Takahiro, Hori, Yoshimi, Umebayashi, Kyohei, Soh, Chieko, Hakozaki, Tomohiro, Toyama, Kazumi, Osumi, Masako, Kondo, Akihiko, Hasunuma, Tomohisa

    Published in Journal of bioscience and bioengineering (01-01-2024)
    “…Geotrichum candidum is a dimorphic yeast used in cheese processing. To our knowledge, no major metabolites have been identified to date in G. candidum except…”
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  13. 13

    Sleep Deprivation Increases Facial Skin Yellowness by Matsubara, Akira, Deng, Gang, Gong, Lili, Chew, Eileen, Furue, Masutaka, Xu, Ying, Fang, Bin, Hakozaki, Tomohiro

    Published in Journal of clinical medicine (12-01-2023)
    “…Sleep shortage is a major concern in modern life and induces various psycho-physical disorders, including skin problems. In cosmeceutics, females are aware…”
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  14. 14

    Transcriptomic Analysis of Human Keratinocytes Treated with Galactomyces Ferment Filtrate, a Beneficial Cosmetic Ingredient by Nakajima, Akiko, Sakae, Nahoko, Yan, Xianghong, Hakozaki, Tomohiro, Zhao, Wenzhu, Laughlin, Timothy, Furue, Masutaka

    Published in Journal of clinical medicine (09-08-2022)
    “…Galactomyces ferment filtrate (GFF, Pitera™) is a cosmetic ingredient known to have multiple skin care benefits, such as reducing redness and pore size via the…”
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  15. 15

    Numerical simulation of plasma chemical vapor deposition from silane : Effects of the plasma-substrate distance and hydrogen dilution by KAWASE, M, NAKAI, T, YAMAGUCHI, A, HAKOEAKI, T, HASHIMOTO, K

    Published in Japanese Journal of Applied Physics (01-06-1997)
    “…Rf plasma chemical vapor deposition from silane was numerically analyzed. When a substrate was moved away from the plasma, gas-phase polymerization increased…”
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  16. 16

    Inter- and intra-observer agreement in dermatologists' diagnoses of hyperpigmented facial lesions and development of an algorithm for automated diagnosis by Yu, Peicong, Li, Xiaojie, Huang, Yi, Tey, Hong Liang, Kong, Adams Wai Kin, Hakozaki, Tomohiro, Purwar, Ankur

    Published in Skin research and technology (01-11-2019)
    “…Hyperpigmentation has varied aetio-pathologies. Hence, accurate and reproducible diagnosis of the type of hyperpigmentation is essential for effective…”
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  17. 17

    Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine by Bissett, Donald L, Robinson, Larry R, Raleigh, Patricia S, Miyamoto, Kukizo, Hakozaki, Tomohiro, Li, Jim, Kelm, Gary R

    Published in Journal of cosmetic dermatology (01-03-2007)
    “…Summary Glucosamine has been reported to inhibit melanin production in melanocyte culture. It thus has a potential to reduce hyperpigmentation via topical use…”
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  18. 18

    Real-time chemiluminescent imaging and detection of reactive oxygen species generated in the UVB-exposed human skin equivalent model by Yasui, Hiroyuki, Hakozaki, Tomohiro, Date, Akira, Yoshii, Takashi, Sakurai, Hiromu

    “…The objective of this study is to image and detect reactive oxygen species (ROS) generated in the UVB-exposed three-dimensional human skin equivalent model…”
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  19. 19

    Ultrasound enhanced skin-lightening effect of vitamin C and niacinamide by Hakozaki, Tomohiro, Takiwaki, Hirotsugu, Miyamoto, Kukizo, Sato, Yasuhiro, Arase, Seiji

    Published in Skin research and technology (01-05-2006)
    “…Cutaneous hyperpigmentation occurs in multiple conditions. There is a strong need for the improvement of hyperpigmentation especially among Asian women…”
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  20. 20

    Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-l-phenylalanine and its combination with niacinamide by Bissett, Donald L, Robinson, Larry R, Raleigh, Patricia S, Miyamoto, Kukizo, Hakozaki, Tomohiro, Li, Jim, Kelm, Gary R

    Published in Journal of cosmetic dermatology (01-12-2009)
    “…Summary Objectives  N‐undecyl‐10‐enoyl‐l‐phenylalanine (Sepiwhite®, N‐undecylenoyl phenylalanine), a reported alpha‐melanocyte‐stimulating hormone (MSH)…”
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    Journal Article