Search Results - "Hakomori, Tadashi"

New approach to optimizing risk management of the sticking problem using scale-independent critical material attributes and the quantitative process parameter by Ando, Hirotaka, Hara, Yuko, Sato, Kazunari, Dohi, Masafumi, Hakomori, Tadashi, Yonemochi, Etsuo

“…[Display omitted] In pharmaceutical manufacturing of solid formulations, blending with a lubricant is a key process in preventing sticking during compression…”
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Application of novel compaction indicator for the optimization of compaction conditions based on a compaction simulation study by Takahashi, Takuma, Toyota, Hiroyasu, Kuroiwa, Yosuke, Kondo, Hisami, Dohi, Masafumi, Hakomori, Tadashi, Nakamura, Mitsuhiro, Takeuchi, Hirofumi

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Quantitative evaluation of different rotary tablet presses by compaction velocity based on compaction simulation study by Takahashi, Takuma, Toyota, Hiroyasu, Kuroiwa, Yosuke, Yoshino, Hiroyuki, Kondou, Hisami, Yamashita, Kazunari, Hakomori, Tadashi, Takeuchi, Hirofumi

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Use of Mixer Torque Rheometer to Clarify the Relationship between the Kneading States of Wet Mass and the Dissolution of Final Product in High Shear Granulation by Otsuka, Tomoko, Kuroiwa, Yosuke, Sato, Kazunari, Yamashita, Kazunari, Hakomori, Tadashi, Kimura, Shin-ichiro, Iwao, Yasunori, Itai, Shigeru

“…The properties of wet mass, which indicate the progress of high shear granulation processes, usually have an effect on final product properties, such as tablet…”
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Application of Terahertz Attenuated Total Reflection Spectroscopy to Detect Changes in the Physical Properties of Lactose during the Lubrication Process Required for Drug Formulation by Dohi, Masafumi, Momose, Wataru, Yamashita, Kazunari, Hakomori, Tadashi, Sato, Shusaku, Noguchi, Shuji, Terada, Katsuhide

“…Manufacturing the solid dosage form of an orally administered drug requires lubrication to enhance manufacturability, ensuring that critical quality attributes…”
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Impact of process parameters on Mg–St content and tablet surface wettability in the external lubrication method for a rotary tablet press by Kamiya, Takayuki, Kondo, Hisami, Hiroma, Hiroyuki, Yamashita, Kazunari, Hakomori, Tadashi, Sako, Kazuhiro, Iwao, Yasunori, Noguchi, Shuji, Itai, Shigeru

“…[Display omitted] •Tablet wettability by external lubrication was lower than by internal method.•Tablet wettability can be controlled by the setting of…”
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Effect of the External Lubrication Method for a Rotary Tablet Press on the Adhesion of the Film Coating Layer by Kondo, Hisami, Toyota, Hiroyasu, Kamiya, Takayuki, Yamashita, Kazunari, Hakomori, Tadashi, Imoto, Junko, Kimura, Shin-ichiro, Iwao, Yasunori, Itai, Shigeru

“…External lubrication is a useful method which reduces the adhesion of powder to punches and dies by spraying lubricants during the tableting process. However,…”
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Novel approach to evaluating granulation and segregation level considering the contribution of hydroxypropyl cellulose to the surface property change of granules by Ando, Hirotaka, Nozaki, Yusuke, Sato, Kazunari, Dohi, Masafumi, Hakomori, Tadashi, Yonemochi, Etsuo

“…[Display omitted] The granulation process is critical to the uniformity of not only the active ingredient (API) but also other excipients in granules…”
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Application of terahertz pulse imaging as PAT tool for non-destructive evaluation of film-coated tablets under different manufacturing conditions by Dohi, Masafumi, Momose, Wataru, Yoshino, Hiroyuki, Hara, Yuko, Yamashita, Kazunari, Hakomori, Tadashi, Sato, Shusaku, Terada, Katsuhide

“…Non-destructive evaluation of critical quality attribute of film coated tablet with Terahertz Pulsed Imaging (TPI). [Display omitted] •We analyzed the…”
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Development of extended‐release solid dispersion granules of tacrolimus: evaluation of release mechanism and human oral bioavailability by Tsunashima, Daisuke, Yamashita, Kazunari, Ogawara, Ken‐ichi, Sako, Kazuhiro, Hakomori, Tadashi, Higaki, Kazutaka

“…Objectives We aimed to prepare a once‐daily modified‐release oral formulation of tacrolimus by utilizing an extended‐release granules (ERG). Methods…”
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A Scale-up Approach for Film Coating Process Based on Surface Roughness as the Critical Quality Attribute by Yoshino, Hiroyuki, Hara, Yuko, Dohi, Masafumi, Yamashita, Kazunari, Hakomori, Tadashi, Kimura, Shin-ichiro, Iwao, Yasunori, Itai, Shigeru

“…Scale-up approaches for film coating process have been established for each type of film coating equipment from thermodynamic and mechanical analyses for…”
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