Search Results - "Hakomori, S I"

The Globoseries Glycosphingolipid Sialosyl Galactosyl Globoside Is Found in Urinary Tract Tissues and Is a Preferred Binding Receptor In Vitro for Uropathogenic Escherichia coli Expressing pap-Encoded Adhesins by STAPLETON, A. E, STROUD, M. R, HAKOMORI, S. I, STAMM, W. E

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Enhanced GM3 expression, associated with decreased invasiveness, is induced by brefeldin A in bladder cancer cells by Satoh, M, Ito, A, Nojiri, H, Handa, K, Numahata, K, Ohyama, C, Saito, S, Hoshi, S, Hakomori, S I

“…We reported previously that non-invasive bladder cancer expresses high level of GM3 ganglioside, whereas invasive tumors have low levels. Since…”
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A specific cell surface glycoconjugate controlling cell motility: evidence by functional monoclonal antibodies that inhibit cell motility and tumor cell metastasis by Miyake, Masayuki, Hakomori, Senitiroh

“…The biochemical basis of cell motility has been viewed as a complex process involving cell surface membrane proteins, integrin receptors, growth factors and…”
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Relationship between specific embryonic antigen-4 expression and the androgen dependency of cancer cells and tumour-infiltrating cells in prostate cancer by Shida, Y., Miyata, Y., Hakariya, T., Nakamura, Y., Matsuo, T., Ohba, K., Taima, T., Ito, A., Suda, T., Hakomori, S-I., Saito, S., Sakai, H.

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Inhibition of human immunodeficiency virus (HIV) infection in vitro by anticarbohydrate monoclonal antibodies: peripheral glycosylation of HIV envelope glycoprotein gp120 may be a target for virus neutralization by HANSEN, J.-E. S, CLAUSEN, H, NIELSEN, C, TEGLBJAERG, L. S, HANSEN, L. L, NIELSEN, C. M, DABELSTEEN, E, MATHIESEN, L, HAKOMORI, S.-I, NIELSEN, J. O

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Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions by Hakomori, S

“…Glycosphingolipids (GSLs), or their modified catabolites, at the cell surface modulate transmembrane signal transduction by influencing protein kinases…”
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Incompatible A antigen expressed in tumors of blood group O individuals: immunochemical, immunohistologic, and enzymatic characterization by Clausen, H, Hakomori, S, Graem, N, Dabelsteen, E

“…Monofucosyl type 1 chain A (type 1 Aa) and difucosyl type 1 chain A (ALeb), but not other types of A antigens, have been detected by application of carrier…”
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Structure and function of sphingoglycolipids in transmembrane signalling and cell-cell interactions by Hakomori, S

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Identification of ganglio-N-tetraosylceramide as a new cell surface marker for murine natural killer (NK) cells by Young, Jr, W W, Hakomori, S I, Durdik, J M, Henney, C S

“…The BCG-induced NK cell activity of murine peritoneal exudate cells was abolished by preincubation of effector cells with anti-ganglio-N-tetraosylceramide…”
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Molecular genetic basis of the histo-blood group ABO system by Yamamoto, Fumi-ichiro, Clausen, Henrik, White, Thayer, Marken, John, Hakomori, Sen-itiroh

“…The histo-blood group ABO, the major human alloantigen system, involves three carbohydrate antigens (ABH). A, B and AB individuals express glycosyltransferase…”
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ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex by PHILLIPS, M. L, NUDELMAN, E, GAETA, F. C. A, PEREZ, M, SINGHAL, A. K, HAKOMORI, S.-I, PAULSON, J. C

“…Recruitment of neutrophils to sites of inflammation is mediated in part by endothelial leukocyte adhesion molecule-1 (ELAM-1), which is expressed on activated…”
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Tumor-Associated Carbohydrate Antigens by Hakomori, Sen-itiroh

“…This review concisely surveys (a) the general biochemical characteristics of the carbohydrate changes associated with oncogenic transformation; (b) the…”
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Inhibition of selectin-dependent tumor cell adhesion to endothelial cells and platelets by blocking O-glycosylation of these cells by Kojima, N, Handa, K, Newman, W, Hakomori, S

“…Expression of sialosyl-Le(x) (SLe(x)) and sialosyl-Le(a) (SLe(a)) on tumor cell lines HL60, Colo205, and U937 was greatly suppressed by application of…”
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Possible Role of Ceramide in Defining Structure and Function of Membrane Glycolipids by Kannagi, Reiji, Nudelman, Edward, Hakomori, Sen-Itiroh

“…A possible role of ceramide in defining the carbohydrate structure of glycolipids and the expression of glycolipid function has been proposed, on the basis of…”
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Sphingosine 1-Phosphate, a Specific Endogenous Signaling Molecule Controlling Cell Motility and Tumor Cell Invasiveness by Sadahira, Yoshito, Ruan, Fuqiang, Hakomori, Sen-itiroh, Igarashi, Yasuyuki

“…Sphingosine 1-phosphate (Sph-1-P), the initial product of Sph degradation by Sph kinase, was shown to be a strong inhibitor of cell motility and phagokinesis…”
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Studies on Cell Adhesion and Recognition. I. Extent and Specificity of Cell Adhesion Triggered by Carbohydrate-Reactive Proteins (Glycosidases and Lectins) and by Fibronectin by Rauvala, Heikki, Carter, William G., Hakomori, Sen-Itiroh

“…The extent and the specificity of the initial cell attachment induced by various proteins coated on plastic surfaces have been studied with the following…”
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CD62 and Endothelial Cell-Leukocyte Adhesion Molecule 1 (ELAM-1) Recognize the Same Carbohydrate Ligand, Sialyl-Lewis x by Polley, Margaret J., Phillips, M. Laurie, Wayner, Elizabeth, Nudelman, Edward, Singhal, Anil K., Hakomori, Sen-Itiroh, Paulson, James C.

“…The leukocyte receptor CD62, which is expressed on activated platelets and endothelial cells, is shown to mediate cell adhesion by binding a sialylated…”
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Glycosphingolipids as tumor-associated and differentiation markers by Hakomori, S, Kannagi, R

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Density-dependent recognition of cell surface GM3 by a certain anti- melanoma antibody, and GM3 lactone as a possible immunogen: requirements for tumor-associated antigen and immunogen by Nores, GA, Dohi, T, Taniguchi, M, Hakomori, S

“…A mouse monoclonal antibody M2590, previously established after immunization of mice (C57BL/6) with syngeneic melanoma B16 cells and showing preferential…”
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Therapeutic effect of intradermal injections with difucosyl lactosamine (dimeric Lex) on patients with rheumatoid arthritis by Ochi, T, Hakomori, S, Fujimoto, M, Okamura, M, Owaki, H, Wakitani, S, Shimaoka, Y, Hayashida, K, Tomita, T, Kawamura, S

“…As reported by us, a new myeloid cell population with an oncofetal membrane marker, dimeric Lex (di-Lex; III3FucV3 FucnLc6), was found in the epiphyseal bone…”
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