Search Results - "Haklai, Ronit"

Obituary for Professor Yoel Kloog by Haklai, Ronit, Stein, Reuven

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Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: A new drug combination for cancer therapy by Biran, Anat, Brownstein, Michael, Haklai, Ronit, Kloog, Yoel

“…Histone deacetylase (HDAC) inhibitors, such as valproic acid (VPA), constitute a novel class of anticancer agents that cause an increase in acetylated histones…”
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Galectin-3/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI/II mediated myelin phagocytosis in microglia by Rotshenker, Shlomo, Reichert, Fanny, Gitik, Miri, Haklai, Ronit, Elad-Sfadia, Galit, Kloog, Yoel

“…The removal of degenerated myelin is essential for repair in Wallerian degeneration that follows traumatic injury to axons and in autoimmune demyelinating…”
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Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid) by Zundelevich, Adi, Elad-Sfadia, Galit, Haklai, Ronit, Kloog, Yoel

“…Aberrant Ras pathway functions contribute to the malignant phenotype of lung cancers. Inhibitors of Ras might therefore be considered as potential drugs for…”
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Disruption of Cooperation Between Ras and MycN in Human Neuroblastoma Cells Promotes Growth Arrest by YAARI, Shira, JACOB-HIRSCH, Jasmine, AMARIGLIO, Ninette, HAKLAI, Ronit, RECHAVI, Gideon, KLOOG, Yoel

“…Purpose: Our aim was to examine whether active Ras and MycN cooperation contributes to the malignant phenotype of human neuroblastoma with amplified MycN gene,…”
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The Ras Inhibitor S-trans,trans-Farnesylthiosalicylic Acid Chemosensitizes Human Tumor Cells Without Causing Resistance by Gana-Weisz, Mali, Halaschek-Wiener, Julius, Jansen, Burkhard, Elad, Galit, Haklai, Ronit, Kloog, Yoel

“…Ras transformation requires Ras membrane anchorage, which is promoted by a farnesylcysteine carboxymethyl ester and by additional sequences specific to each…”
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The association between let-7, RAS and HIF-1α in Ewing Sarcoma tumor growth by Hameiri-Grossman, Michal, Porat-Klein, Adi, Yaniv, Isaac, Ash, Shifra, Cohen, Ian J, Kodman, Yona, Haklai, Ronit, Elad-Sfadia, Galit, Kloog, Yoel, Chepurko, Elena, Feinmesser, Meora, Issakov, Josephine, Sher, Osnat, Luria, Drorit, Kollender, Yehuda, Weizman, Avraham, Avigad, Smadar

“…Ewing Sarcoma (ES) is the second most common primary malignant bone tumor in children and adolescents. microRNAs (miRNAs) are involved in cancer as tumor…”
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Abstract A76: Ras pathway and HIF-1α contribute to the aggressiveness of Ewing sarcoma by Hameiri-Grossman, Michal, Porat-Klein, Adi, Cohen, Ian J., Ash, Shifra, Kloog, Yoel, Haklai, Ronit, Elad-Sfadia, Galit, Weizman, Avraham, Yaniv, Isaac, Avigad, Smadar

“…Aim: Ewing sarcoma (ES) is the second most common and aggressive primary malignant bone tumor in children and adolescents. The hallmarks of the tumor are…”
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Ras inhibition attenuates myocardial ischemia–reperfusion injury by Pando, Rakefet, Cheporko, Yelena, Haklai, Ronit, Maysel-Auslender, Sofia, Keren, Gad, George, Jacob, Porat, Eyal, Sagie, Alex, Kloog, Yoel, Hochhauser, Edith

“…Hemodynamic and histological staining of hearts treated pre- and post-LAD ligation with FTS showed better function and a reduction in the area of irreversible…”
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The Ras antagonist farnesylthiosalicylic acid ameliorates experimental myocarditis in the rat by Pando, Rakefet, Barshack, Iris, Raz, Alon, Luboshits, Galia, Haklai, Ronit, Maysel-Auslender, Sofia, Kloog, Yoel, Keren, Gad, George, Jacob

“…Abstract Background Myocarditis is an inflammatory disorder of the heart in which T lymphocytes have a central role. No effective treatment is currently at…”
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