Search Results - "Hakimi, Jalil"
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The Gene Associated with Trichorhinophalangeal Syndrome in Humans Is Overexpressed in Breast Cancer
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2005)“…A comprehensive differential gene expression screen on a panel of 54 breast tumors and >200 normal tissue samples using DNA microarrays revealed 15 genes…”
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An adjuvant-modulated vaccine response in human whole blood
Published in Human vaccines & immunotherapeutics (02-09-2017)“…The restimulation of an immune memory response by in vitro culture of blood cells with a specific antigen has been used as a way to gauge immunity to vaccines…”
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Significance of the CAG repeat polymorphism of the androgen receptor gene in prostate cancer progression
Published in The Journal of urology (01-08-2000)“…The CAG repeat polymorphism of the androgen receptor gene has been associated with an increased prostate cancer risk, and the repeat length correlated with…”
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Screening Vaccine Formulations in Fresh Human Whole Blood
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2017)“…Monitoring the immunological functionality of vaccine formulations is critical for vaccine development. While the traditional approach using established animal…”
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A high ratio of IC31® adjuvant to antigen is necessary for H4 TB vaccine immunomodulation
Published in Human vaccines & immunotherapeutics (03-06-2015)“…A tuberculosis (TB) vaccine consisting of a recombinant fusion protein (H4) and a novel TLR9 adjuvant (IC31) is in clinical development. To better understand…”
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A sensitive flow cytometry-based cytotoxic T-lymphocyte assay through detection of cleaved caspase 3 in target cells
Published in Journal of immunological methods (01-09-2005)“…We describe a highly sensitive flow cytometry-based CTL assay using the cleavage of caspase 3 in target cells as a readout. The assay involved labeling of…”
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Screening vaccine formulations for biological activity using fresh human whole blood
Published in Human vaccines & immunotherapeutics (28-04-2014)“…Understanding the relevant biological activity of any pharmaceutical formulation destined for human use is crucial. For vaccine-based formulations, activity…”
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Is Uterine Papillary Serous Adenocarcinoma a Manifestation of the Hereditary Breast–Ovarian Cancer Syndrome?
Published in Gynecologic oncology (01-12-2000)“…Background. Uterine papillary serous carcinoma (UPSC) shares common pathologic, genetic, and clinical features with other serous cancers of müllerian origin…”
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A rapid fluorescent multiplexed-PCR analysis (FMPA) for founder mutations in the BRCA1 and BRCA2 genes
Published in Clinical genetics (01-03-2000)“…Mutations of the BRCA1 and BRCA2 genes account for approximately 80% of hereditary breast/ovarian cancer families, but the size of these two genes makes…”
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A rapid fluorescent multiplexed‐PCR analysis (FMPA) for founder mutations in the BRCA 1 and BRCA 2 genes
Published in Clinical genetics (01-03-2000)“…Mutations of the BRCA 1 and BRCA 2 genes account for approximately 80% of hereditary breast/ovarian cancer families, but the size of these two genes makes…”
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