Search Results - "Hake, Johan E."
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Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice
Published in Biophysical journal (05-11-2013)“…Contractile function of cardiac cells is driven by the sliding displacement of myofilaments powered by the cycling myosin crossbridges. Critical to this…”
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2
Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle
Published in Circulation. Arrhythmia and electrophysiology (01-12-2014)“…BACKGROUND—Early afterdepolarizations (EADs) are triggers of cardiac arrhythmia driven by L-type Ca current (ICaL) reactivation or sarcoplasmic reticulum Ca…”
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3
Modeling Calcium Sparks in a Three-Dimensional Reconstruction of a Cardiac Calcium Release Unit
Published in Biophysical journal (01-01-2012)Get full text
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4
Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes with Realistic T-Tubule Geometries
Published in Frontiers in physiology (01-01-2012)“…The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations (t-tubules) that are essential for efficient cardiac…”
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5
cbcbeat: an adjoint-enabled framework for computational cardiac electrophysiology
Published in Journal of open source software (31-05-2017)Get full text
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Non-equilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricle
Published in Circulation. Arrhythmia and electrophysiology (18-09-2014)Get full text
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Modeling effects of L-type ca(2+) current and na(+)-ca(2+) exchanger on ca(2+) trigger flux in rabbit myocytes with realistic T-tubule geometries
Published in Frontiers in physiology (2012)“…The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations (t-tubules) that are essential for efficient cardiac…”
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8
Automated adjoints of coupled PDE-ODE systems
Published 25-08-2017“…Mathematical models that couple partial differential equations (PDEs) and spatially distributed ordinary differential equations (ODEs) arise in biology,…”
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