Search Results - "Hake, Johan E."

  • Showing 1 - 8 results of 8
Refine Results
  1. 1

    Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice by Kekenes-Huskey, Peter M., Liao, Tao, Gillette, Andrew K., Hake, Johan E., Zhang, Yongjie, Michailova, Anushka P., McCulloch, Andrew D., McCammon, J. Andrew

    Published in Biophysical journal (05-11-2013)
    “…Contractile function of cardiac cells is driven by the sliding displacement of myofilaments powered by the cycling myosin crossbridges. Critical to this…”
    Get full text
    Journal Article
  2. 2

    Nonequilibrium Reactivation of Na+ Current Drives Early Afterdepolarizations in Mouse Ventricle by Edwards, Andrew G, Grandi, Eleonora, Hake, Johan E, Patel, Sonia, Li, Pan, Miyamoto, Shigeki, Omens, Jeffrey H, Heller Brown, Joan, Bers, Donald M, McCulloch, Andrew D

    “…BACKGROUND—Early afterdepolarizations (EADs) are triggers of cardiac arrhythmia driven by L-type Ca current (ICaL) reactivation or sarcoplasmic reticulum Ca…”
    Get full text
    Journal Article
  3. 3
  4. 4

    Modeling Effects of L-Type Ca2+ Current and Na+-Ca2+ Exchanger on Ca2+ Trigger Flux in Rabbit Myocytes with Realistic T-Tubule Geometries by Kekenes-Huskey, Peter M., Cheng, Yuhui, Hake, Johan E., Sachse, Frank B., Bridge, John H., Holst, Michael J., McCammon, J. Andrew, McCulloch, Andrew D., Michailova, Anushka P.

    Published in Frontiers in physiology (01-01-2012)
    “…The transverse tubular system of rabbit ventricular myocytes consists of cell membrane invaginations (t-tubules) that are essential for efficient cardiac…”
    Get full text
    Journal Article
  5. 5
  6. 6
  7. 7
  8. 8

    Automated adjoints of coupled PDE-ODE systems by Farrell, Patrick E, Hake, Johan E, Funke, Simon W, Rognes, Marie E

    Published 25-08-2017
    “…Mathematical models that couple partial differential equations (PDEs) and spatially distributed ordinary differential equations (ODEs) arise in biology,…”
    Get full text
    Journal Article