Search Results - "Hakami, Hana"
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1
Fibulin-4 exerts a dual role in LTBP-4L–mediated matrix assembly and function
Published in Proceedings of the National Academy of Sciences - PNAS (08-10-2019)“…Elastogenesis is a hierarchical process by which cells form functional elastic fibers, providing elasticity and the ability to regulate growth factor…”
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Journal Article -
2
PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells
Published in BMC cancer (27-07-2016)“…Triple-negative breast cancer (TNBC) is an aggressive histological subtype with limited treatment options and very poor prognosis following progression after…”
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Journal Article -
3
Venom of the desert black snake Walterinnesia aegyptia enhances anti-tumor immunity via its beneficial modulatory effects on pro- and anti-tumorigenic inflammatory mediators in cultured colon cancer cells
Published in Toxicology research (Cambridge) (01-12-2021)“…The role of inflammation in colon cancer is understood as a well-accepted factor that has the tendency to release multiple pro- and anti-tumorigenic…”
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Journal Article -
4
Identification of novel genomic imbalances in Saudi patients with congenital heart disease
Published in Molecular cytogenetics (25-01-2018)“…Quick genetic diagnosis of a patient with congenital heart disease (CHD) is quite important for proper health care and management. Copy number variations…”
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5
Identification of the Cell Receptors for Fibulin-4 and Latent Transforming Growth Factor-β Binding Protein-4, and Their Functional Roles in Elastogenesis
Published 01-01-2020“…Introduction: Elastic fibers are abundant extracellular matrix (ECM) components that provide tissues such as skin, blood vessels and lungs with elasticity…”
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Dissertation -
6
Mutations in NALCN Cause an Autosomal-Recessive Syndrome with Severe Hypotonia, Speech Impairment, and Cognitive Delay
Published in American journal of human genetics (03-10-2013)“…Sodium leak channel, nonselective (NALCN) is a voltage-independent and cation-nonselective channel that is mainly responsible for the leaky sodium transport…”
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Journal Article -
7
PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis
Published in Matrix biology (01-08-2021)“…•FBLN5 is a substrate of PAD2 and its citrullination in lungs undergoes a temporal change correlating with in vivo elastogenesis.•Citrullination of FBLN5…”
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Journal Article -
8
Assessment of tumor-suppressive inflammatory tendency of Echis coloratus venom against colon carcinogenesis, via up-regulation of anti-tumorigenic inflammatory cells and down-regulation of pro-tumorigenic inflammatory cells, in colon cancer cell lines
Published in Toxin reviews (02-01-2022)“…The present study aims to investigate the tumor-suppressive inflammatory tendency of Echis coloratus snake venom against colon cancer. For this purpose, venom…”
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Journal Article -
9
The anti-cancer effect of Echis coloratus and Walterinnesia aegyptia venoms on colon cancer cells
Published in Toxin reviews (03-07-2021)“…Colorectal cancer (CRC) is one of the most prevalent causes of cancer mortality worldwide. Saudi patients are more likely to present CRC at advanced disease…”
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Journal Article