Search Results - "Hakami, Abdulrahim R."
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Targeting the RBD of Omicron Variant (B.1.1.529) with Medicinal Phytocompounds to Abrogate the Binding of Spike Glycoprotein with the hACE2 Using Computational Molecular Search and Simulation Approach
Published in Biology (Basel, Switzerland) (07-02-2022)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus continues to inflict chaos globally. The emergence of a novel Omicron variant…”
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Nanomaterials-Based Novel Immune Strategies in Clinical Translation for Cancer Therapy
Published in Molecules (Basel, Switzerland) (26-01-2023)“…Immunotherapy shows a lot of promise for addressing the problems with traditional cancer treatments. Researchers and clinicians are working to create…”
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Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach
Published in Vaccines (Basel) (25-01-2022)“…Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over some time, thus protecting the bacteria against antibiotics. AR is…”
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Development and In Vitro Characterization of Antibiotic-Loaded Nanocarriers for Dental Delivery
Published in Molecules (Basel, Switzerland) (24-03-2023)“…The aim of this research work was to formulate and evaluate ciprofloxacin hydrochloride-loaded nanocarriers for treating dental infections and bone…”
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Studying the Effect of Particulate Matter as SARS-CoV-2 Transmitters
Published in Journal of public health research (21-10-2021)“…Background Studies of risk factors are especially valuable at this difficult time in the midst of a pandemic. High levels of particulate matter (PM) represent…”
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Blue Biotechnology: Computational Screening of Sarcophyton Cembranoid Diterpenes for SARS-CoV-2 Main Protease Inhibition
Published in Marine drugs (13-07-2021)“…The coronavirus pandemic has affected more than 150 million people, while over 3.25 million people have died from the coronavirus disease 2019 (COVID-19). As…”
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Detection of chikungunya virus in the Southern region, Saudi Arabia
Published in Virology journal (20-09-2021)“…Despite the fact that the chikungunya viral infection is a neglected disease, complications such as hemorrhagic fever, arthritis, and lymphopenia remain a…”
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Virtual Screening and Molecular Docking Studies for Discovery of Potential RNA-Dependent RNA Polymerase Inhibitors
Published in Crystals (Basel) (01-05-2021)“…The current COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Globally, this pandemic has affected over…”
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In Vitro Potent Anticancer, Antifungal, and Antioxidant Efficacy of Walnut (Juglans regia L.) Genotypes
Published in Agronomy (Basel) (01-04-2023)“…Walnuts are one of the healthiest foods in the world because they are one of the best sources of beneficial nutrients, minerals, and antioxidants. They also…”
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Correlation of circulating endothelial markers in COVID-19 patients admitted to the intensive care unit with laboratory data
Published in European journal of inflammation (01-10-2023)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still a global concern with high morbidity and mortality rates. The role of endothelial cells…”
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Antimicrobial efficacy of different pulp-capping materials against Enterococcus faecalis: An In vitro study
Published in Journal of pharmacy & bioallied science (01-06-2021)“…Aim: The present study aims to assess the antimicrobial action of three different pulp-capping agents against Enterococcus faecalis. Materials and Methods:…”
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Application of CRISPR-Cas System to Mitigate Superbug Infections
Published in Microorganisms (Basel) (26-09-2023)“…Multidrug resistance in bacterial strains known as superbugs is estimated to cause fatal infections worldwide. Migration and urbanization have resulted in…”
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Selection of SARS-CoV-2 main protease inhibitor using structure-based virtual screening
Published in Future medicinal chemistry (01-01-2022)“…Conserved domains within SARS-CoV-2 nonstructural proteins represent key targets for the design of novel inhibitors. The authors aimed to identify potential…”
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High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma
Published in Journal of computer-aided molecular design (01-12-2021)“…Paradoxical Raf activation via Raf dimerization is a major drawback of wild/mutant B-Raf inhibitors. Herein, we report that CB-1 a novel, potent B-Raf/c-Raf…”
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Effectiveness of single versus multiple sessions of photodynamic therapy as adjunct to scaling and root planing on periodontopathogenic bacteria in patients with periodontitis
Published in Photodiagnosis and photodynamic therapy (01-12-2020)“…•All patients had Grade B/Stage I periodontitis.•The patient population comprised of non-smoking systemically healthy individuals.•Efficacy of a single versus…”
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Role of miRNA-495 and NRXN-1 and CNTN-1 mRNA Expression and Its Prognostic Importance in Breast Cancer Patients
Published in Journal of oncology (08-10-2021)“…Breast cancer is a heterogeneous disease in which genetic factors are involved in disease worsening and higher mortality. Epidemiological and clinical research…”
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Antibacterial evaluation of 2-(6-Chloro-2-p-tolylquinazolin-4-ylthio) acetonitrile against pathogenic bacterial isolates with special reference to biofilm formation inhibition and anti-adherence properties
Published in Journal of King Saud University. Science (01-09-2024)“…Evaluating the effectiveness of a specific quinazoline molecule with antibacterial activity on microorganisms as a potential antibiotic substitution. A variety…”
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Serological markers of transfusion transmissible infections and ABO blood groups in Najran, Saudi Arabia
Published in Saudi medical journal (01-07-2024)“…To ascertain the prevalence of transfusion transmissible infections (TTIs) across diverse donor groups in the Najran province. Additionally, to establish a…”
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Non-ionic detergents facilitate non-specific binding of M13 bacteriophage to polystyrene surfaces
Published in Journal of virological methods (01-09-2015)“…•Non-specific interactions observed during screening of M13-displayed peptide libraries by ELISA.•Interaction between phage and polystyrene surfaces is caused…”
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The correlation between severe complications and blood group types in COVID-19 patients; with possible role of T polyagglutination in promoting thrombotic tendencies
Published in AIMS medical science (01-03-2023)“…Introduction Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still posing detrimental effects on…”
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