Search Results - "Hakala, H."

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    Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase by Hakala, Joshua H., Laseke, Amanda J., Koza, Anya L., St. Maurice, Martin

    Published in Biochemistry (Easton) (06-09-2022)
    “…Biotin-dependent enzymes employ a carrier domain to efficiently transport reaction intermediates between distant active sites. The translocation of this…”
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    Journal Article
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    dissociative fluorescence enhancement technique for one-step time-resolved immunoassays by Blomberg, Kaj R, Mukkala, Veli-Matti, Hakala, Harri H. O, Mäkinen, Pauliina H, Suonpää, Mikko U, Hemmilä, Ilkka A

    Published in Analytical and bioanalytical chemistry (01-02-2011)
    “…The limitation of current dissociative fluorescence enhancement techniques is that the lanthanide chelate structures used as molecular probes are not stable…”
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    Journal Article
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    Introduction of Lanthanide(III) Chelates to Oligopeptides on Solid Phase by Peuralahti, Jari, Hakala, Harri, Mukkala, Veli-Matti, Loman, Kristiina, Hurskainen, Pertti, Mulari, Outi, Hovinen, Jari

    Published in Bioconjugate chemistry (01-07-2002)
    “…The synthesis of oligopeptide building blocks for the introduction of nonluminescent and luminescent lanthanide(III) chelates to the oligopeptide structure on…”
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    Journal Article
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    Chromatographic Purification of Natural Lycopene by Hakala, Sari H, Heinonen, I. Marina

    Published in Journal of agricultural and food chemistry (01-06-1994)
    “…The natural lycopene isolation method was developed in three steps. First, carotenoids were extracted from tomato puree with petroleum ether; next, the…”
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    Journal Article
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    Comparison of biomaterials and extracellular matrices as a culture platform for multiple, independently derived human embryonic stem cell lines by Hakala, Heidi, Rajala, Kristiina, Ojala, Marisa, Panula, Sarita, Areva, Sami, Kellomäki, Minna, Suuronen, Riitta, Skottman, Heli

    Published in Tissue engineering. Part A (01-07-2009)
    “…Long-term in vitro culture of undifferentiated human embryonic stem cells (hESCs) traditionally requires a fibroblast feeder cell layer. Using feeder cells in…”
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    Journal Article
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    Versatile Strategy for Oligonucleotide Derivatization. Introduction of Lanthanide(III) Chelates to Oligonucleotides by Hovinen, Jari, Hakala, Harri

    Published in Organic letters (09-08-2001)
    “…Novel nucleosidic phosphoramidite blocks were synthesized by a Mitsunobu reaction between 2‘-deoxy-5‘-O-(4,4‘-dimethoxytrityl)uridine and a primary alcohol…”
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    Journal Article
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    Measuring the Positioning and Translocation of the Swinging‐Arm Domain of Pyruvate Carboxylase by Hakala, Joshua H, St. Maurice, Martin

    Published in The FASEB journal (01-04-2017)
    “…Abstract only A central goal of studies on large, multi‐domain enzymes such as polyketide synthases and fatty acid synthase is to reveal the mechanism(s)…”
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    Journal Article
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    Modeling the silicon–hafnia interface by Nieminen, R.M., Hakala, M.H., Foster, A.S.

    “…We report first-principles calculations of the structure and electronic properties of several different silicon–hafnia interfaces. The structures have been…”
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    Journal Article Conference Proceeding
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    Oligonucleotide conjugates based on acyclonucleosides and their use in DNA hybridization assays by Hakala, Harri, Ollikka, Pia, Degerholm, Jenni, Hovinen, Jari

    Published in Tetrahedron (21-10-2002)
    “…Synthesis of two oligonucleotide building blocks based on acyclonucleosides ( 10 , 11 ) which enable the introduction of several nonluminescent and luminescent…”
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    Journal Article
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    Evaluation of system components for mobile navigation applications by Hakala, H.

    “…A concept for the evaluation of navigation components with known system requirements and limitations makes use of modern structured analysis and design methods…”
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    Conference Proceeding
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    Solid-Phase Synthesis of Oligonucleotides Labeled with Luminescent Lanthanide(III) Chelates by Jaakkola, Lassi, Peuralahti, Jari, Hakala, Harri, Kunttu, Jenni, Tallqvist, Pekka, Mukkala, Veli-Matti, Ylikoski, Alice, Hovinen, Jari

    Published in Bioconjugate chemistry (01-05-2005)
    “…The synthesis of phosphoramidite building blocks that allow introduction of luminescent europium(III), terbium(III), dysprosium(III), and samarium(III)…”
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    Journal Article
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    Caspase multiplexing: simultaneous homogeneous time-resolved quenching assay (TruPoint) for caspases 1, 3, and 6 by Karvinen, Jarkko, Elomaa, Annika, Mäkinen, Maija-Liisa, Hakala, Harri, Mukkala, Veli-Matti, Peuralahti, Jari, Hurskainen, Pertti, Hovinen, Jari, Hemmilä, Ilkka

    Published in Analytical biochemistry (15-02-2004)
    “…Caspases are a group of cysteine proteases involved in apoptosis and inflammation. A multiparametric homogeneous assay capable of measuring activity of three…”
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    Journal Article
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    Development of luminescent Sm(III) chelates containing hexadentate to nonadentate ligands: synthesis, photophysical properties and coupling to biomolecules by Hakala, Harri, Liitti, Päivi, Peuralahti, Jari, Karvinen, Jarkko, Mukkala, Veli-Matti, Hovinen, Jari

    Published in Journal of luminescence (01-05-2005)
    “…Seventeen novel samarium (Sm)(III) chelates containing two iminodiacetic acid moieties were synthesised and their luminescence properties were measured with…”
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    Journal Article
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    Hybridization Properties of Support-Bound Oligonucleotides: The Effect of the Site of Immobilization on the Stability and Selectivity of Duplex Formation by Ketomaeki, K, Hakala, H, Kuronen, O, Loennberg, H

    Published in Bioconjugate chemistry (01-07-2003)
    “…Four 12-mer oligodeoxyribonucleotide sequences were immobilized to uniformly sized (50 mu m) polymer particles through C5-tethered thymine and N…”
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    Journal Article
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    Hybridization Properties of Support-Bound Oligonucleotides:  The Effect of the Site of Immobilization on the Stability and Selectivity of Duplex Formation by Ketomäki, Kaisa, Hakala, Harri, Kuronen, Outi, Lönnberg, Harri

    Published in Bioconjugate chemistry (16-07-2003)
    “…Four 12-mer oligodeoxyribonucleotide sequences were immobilized to uniformly sized (50 μm) polymer particles through C5-tethered thymine and N4-tethered…”
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    Journal Article