Search Results - "Hak, A"

Adult-onset autoinflammation caused by somatic mutations in UBA1: A Dutch case series of patients with VEXAS by van der Made, Caspar I., Potjewijd, Judith, Hoogstins, Annemiek, Willems, Huub P.J., Kwakernaak, Arjan J., de Sevaux, Ruud G.L., van Daele, Paul L.A., Simons, Annet, Heijstek, Marloes, Beck, David B., Netea, Mihai G., van Paassen, Pieter, Elizabeth Hak, A., van der Veken, Lars T., van Gijn, Marielle E., Hoischen, Alexander, van de Veerdonk, Frank L., Leavis, Helen L., Rutgers, Abraham

“…A novel autoinflammatory syndrome was recently described in male patients who harbored somatic mutations in the X-chromosomal UBA1 gene. These patients were…”
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Menopause, postmenopausal hormone use and risk of incident gout by Hak, A Elisabeth, Curhan, Gary C, Grodstein, Francine, Choi, Hyon K

“…To prospectively study the relation between menopause, postmenopausal hormone use and risk of gout, since female sex hormones have been postulated to decrease…”
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The paramount importance of pattern recognition in auto-inflammatory diseases in reducing time to diagnosis by Hak, A E

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Systemic autoimmune disease as a cause of death: mortality burden and comorbidities by Mitratza, Marianna, Klijs, Bart, Hak, A Elisabeth, Kardaun, Jan W P F, Kunst, Anton E

“…Abstract Objectives Systemic autoimmune diseases (SAIDs) have chronic trajectories and share characteristics of self-directed inflammation, as well as aspects…”
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Systemic lupus erythematosus and the risk of cardiovascular disease: Results from the nurses' health study by Hak, A. Elisabeth, Karlson, Elizabeth W., Feskanich, Diane, Stampfer, Meir J., Costenbader, Karen H.

“…Objective Systemic lupus erythematosus (SLE) has been associated with an increased risk of cardiovascular disease. However, prospective population‐based data…”
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Menopause, postmenopausal hormone use and serum uric acid levels in US women--the Third National Health and Nutrition Examination Survey by Hak, A Elisabeth, Choi, Hyon K

“…Despite the substantial prevalence of gout in the ageing female population, female hormonal influence has not been comprehensively examined. We evaluated and…”
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Subclinical hypothyroidism is an independent risk factor for atherosclerosis and myocardial infarction in elderly women : The Rotterdam Study by HAK, A. E, POLS, H. A. P, VISSER, T. J, DREXHAGE, H. A, HOFMAN, A, WITTEMAR, J. C. M

“…Overt hypothyroidism has been found to be associated with cardiovascular disease. Whether subclinical hypothyroidism and thyroid autoimmunity are also risk…”
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Nailfold capillary abnormalities in childhood-onset systemic lupus erythematosus: a cross-sectional study compared with healthy controls by Schonenberg-Meinema, Dieneke, Bergkamp, Sandy C, Nassar-Sheikh Rashid, Amara, van der Aa, Leontien B, de Bree, Godelieve J, ten Cate, Rebecca, Cutolo, Maurizio, Hak, A Elisabeth, Hissink Muller, Petra CE, van Onna, Marieke, Kuijpers, Taco W, Smith, Vanessa, van den Berg, J Merlijn

“…Objectives For selection of high-risk systemic lupus erythematosus (SLE) patients it is necessary to obtain indicators of disease severity that predict disease…”
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IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study by Al-Soudi, A, Doorenspleet, M E, Esveldt, R E, Burgemeister, L T, Hak, A E, van den Born, B J H, Tas, S W, van Vollenhoven, R F, Klarenbeek, P L, de Vries, N

“…An important limitation in granulomatosis with polyangiitis (GPA) is the lack of disease activity markers. Immunoglobulin G4-positive (IgG4 ) B cells and…”
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Porto-sinusoidal vascular disorder and nephrotic-range proteinuria due to venous vasculitis in Behçet's disease by van der Houwen, T.B., Annink, M.E., Roelofs, J.J.T.H., Takkenberg, R.B., van Laar, J.A.M., van der Weerd, N.C., Hak, A.E., Kwakernaak, A.J.

“…Behçet's disease (BD) is an autoinflammatory disease with multifactorial and polygenic etiology, potentially involving arteries and veins of any size resulting…”
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Progression of Aortic Calcification Is Associated With Metacarpal Bone Loss During Menopause: A Population-Based Longitudinal Study by Hak, A Elisabeth, Pols, Huibert A. P, van Hemert, Albert M, Hofman, Albert, Witteman, Jacqueline C. M

“…Atherosclerosis and osteoporosis are major causes of morbidity and mortality in postmenopausal women and have been suggested to be associated. No study has…”
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Unexplained early-onset lacunar stroke and inflammatory skin lesions: Consider ADA2 deficiency by Westendorp, Willeke F, Nederkoorn, Paul J, Aksentijevich, Ivona, Hak, A Elisabeth, Lichtenbelt, Klaske D, Braun, Kees P.J

“…We report 2 brothers who presented at young age with multiple lacunar strokes, inflammatory skin rash, and a range of neurologic symptoms…”
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Associations of C-Reactive Protein With Measures of Obesity, Insulin Resistance, and Subclinical Atherosclerosis in Healthy, Middle-Aged Women by Hak, A Elisabeth, Stehouwer, Coen D.A, Bots, Michiel L, Polderman, Kees H, Schalkwijk, Casper G, Westendorp, Iris C.D, Hofman, Albert, Witteman, Jacqucline C.M

“…Obesity, the insulin resistance syndrome, and atherosclerosis are closely linked and may all be determinants of an increased acute-phase response. In this…”
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Associations Between Child Maltreatment, Inflammation, and Comorbid Metabolic Syndrome to Depressed Mood in a Multiethnic Urban Population: The HELIUS Study by Willemen, Fabienne E M, van Zuiden, Mirjam, Zantvoord, Jasper B, de Rooij, Susanne R, van den Born, Bert-Jan H, Hak, A Elisabeth, Thomaes, Kathleen, Segeren, Menno, Elsenburg, Leonie K, Lok, Anja

“…Child maltreatment is a common negative experience and has potential long-lasting adverse consequences for mental and physical health, including increased risk…”
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Assessment of reproductive toxicity of gold nanoparticles and its reversibility in male albino rats by Abdulhaq, Nancy A., Elnady, Dina A., Abo El-atta, Hend M., El-Morsi, Doaa A., Gad El-Hak, Seham A.

“…Nanotechnology has become a trending area in science all over the world. Although gold nanoparticles (AuNPs) have been utilized widely in biomedical fields,…”
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Acrocyanosis after neoadjuvant ipilimumab plus nivolumab: a case report by Reijers, Irene L M, Hilhorst, Marc, Tan, Melanie, Klarenbeek, Paul L, Hak, A Elisabeth, Blank, Christian U

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Clinical Symptoms, Laboratory Parameters and Long-Term Follow-up in a National DADA2 Cohort by Andriessen, Marie Valérie E., Legger, G. Elizabeth, Bredius, Robbert G. M., van Gijn, Marielle E., Hak, A. Elisabeth, Muller, Petra C. E. Hissink, Kamphuis, Sylvia, Klouwer, Femke C. C., Kuijpers, Taco W., Leavis, Helen L., Nierkens, Stefan, Rutgers, Abraham, van der Veken, Lars T., van Well, Gijs T. J., Mulders-Manders, Catharina M., van Montfrans, Joris M.

“…Deficiency of adenosine deaminase-2 (DADA2) is an autosomal recessive autoinflammatory disease with an extremely variable disease presentation. This paper…”
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Neurological phenotype of adenosine deaminase 2 deficient patients: a cohort study by Verschoof, Merelijne A., Meenen, Laura C. C., Andriessen, M. Valérie E., Brinkman, Daniëlle M. C., Kamphuis, Sylvia, Kuijpers, Taco W., Leavis, Helen L., Legger, G. Elizabeth, Mulders‐Manders, Catharina M., Pagter, Anne P. J., Rutgers, Abraham, Well, Gijs T. J., Coutinho, Jonathan M., Hak, A. Elisabeth, Montfrans, Joris M., Klouwer, Femke C. C.

“…Background and purpose Patients with adenosine deaminase 2 (ADA2) deficiency can present with various neurological manifestations due to vasculopathies and…”
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Dysregulated Fcγ receptor IIa‐induced cytokine production in dendritic cells of lupus nephritis patients by Newling, M., Fiechter, R. H., Sritharan, L., Hoepel, W., Burgsteden, J. A., Hak, A. E., Vollenhoven, R. F., Sande, M. G. H., Baeten, D. L. P., den Dunnen, J.

“…Summary Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown etiology. One of the key factors associated with SLE pathogenesis is excessive…”
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Not Everything Is as It Seems: A Case Series and Overview of Diseases Mimicking Antineutrophil Cytoplasmic Antibody-Associated Vasculitis by Houben, Eline, de Groot, Pieter F, Vegting, Yosta, Vos, Josephine M. I, Nur, Erfan, Hilhorst, Marc L, Hak, A. E. (Liesbeth), Kwakernaak, Arjan J

“…Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare heterogeneous disease in which treatment must be initiated early to prevent…”
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