Search Results - "Hajszan, Tibor"

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder by Kang, Hyo Jung, Voleti, Bhavya, Hajszan, Tibor, Rajkowska, Grazyna, Stockmeier, Craig A, Licznerski, Pawel, Lepack, Ashley, Majik, Mahesh S, Jeong, Lak Shin, Banasr, Mounira, Son, Hyeon, Duman, Ronald S

“…Ronald Duman and colleagues report that synapse number is reduced in subjects with major depressive disorder. This is associated with decreased expression of…”
Get full text

Bisphenol A prevents the synaptogenic response to estradiol in hippocampus and prefrontal cortex of ovariectomized nonhuman primates by Leranth, Csaba, Hajszan, Tibor, Szigeti-Buck, Klara, Bober, Jeremy, MacLusky, Neil J

“…Exposure measurements from several countries indicate that humans are routinely exposed to low levels of bisphenol A (BPA), a synthetic xenoestrogen widely…”
Get full text

Remodeling of Hippocampal Spine Synapses in the Rat Learned Helplessness Model of Depression by Hajszan, Tibor, Dow, Antonia, Warner-Schmidt, Jennifer L, Szigeti-Buck, Klara, Sallam, Nermin L, Parducz, Arpad, Leranth, Csaba, Duman, Ronald S

“…Background Although it has been postulated for many years that depression is associated with loss of synapses, primarily in the hippocampus, and that…”
Get full text

Androgens Increase Spine Synapse Density in the CA1 Hippocampal Subfield of Ovariectomized Female Rats by Leranth, Csaba, Hajszan, Tibor, MacLusky, Neil J

“…The effects of androgen on the density of spine synapses on pyramidal neurons in the CA1 area of the hippocampus were studied in ovariectomized (OVX) adult…”
Get full text

Role of androgens and the androgen receptor in remodeling of spine synapses in limbic brain areas by Hajszan, Tibor, MacLusky, Neil J., Leranth, Csaba

“…Accumulating evidence indicate that structural synaptic plasticity in limbic areas plays a vital role not only in normal brain functions, such as cognition and…”
Get full text

Effects of Androgens and Estradiol on Spine Synapse Formation in the Prefrontal Cortex of Normal and Testicular Feminization Mutant Male Rats by Hajszan, Tibor, MacLusky, Neil J, Johansen, Jamie A, Jordan, Cynthia L, Leranth, Csaba

“…Recent studies suggest that, in female monkeys and rats, estrogens elicit dendritic spine synapse formation in the prefrontal cortex, an area that, similar to…”
Get full text

Subchronic Phencyclidine Treatment Decreases the Number of Dendritic Spine Synapses in the Rat Prefrontal Cortex by Hajszan, Tibor, Leranth, Csaba, Roth, Robert H.

“…A growing body of evidence suggests the existence of synaptic pathology in schizophrenia. Here we used the phencyclidine schizophrenia model to directly…”
Get full text

Intrinsic vesicular glutamate transporter 2-immunoreactive input to septohippocampal parvalbumin-containing neurons: Novel glutamatergic local circuit cells by Hajszan, Tibor, Alreja, Meenakshi, Leranth, Csaba

“…Glutamatergic influence on the medial septum diagonal band of Broca complex (MSDB) is a crucial and powerful driver of hippocampal theta rhythm and associated…”
Get full text

Hypocretin/Orexin Innervation and Excitation of Identified Septohippocampal Cholinergic Neurons by Wu, Min, Zaborszky, Laszlo, Hajszan, Tibor, van den Pol, Anthony N, Alreja, Meenakshi

“…Hypothalamic fibers containing the wake-promoting peptides, hypocretins (Hcrts) or orexins, provide a dense innervation to the medial septum-diagonal band of…”
Get full text

Effects of Dehydroepiandrosterone and Flutamide on Hippocampal CA1 Spine Synapse Density in Male and Female Rats: Implications for the Role of Androgens in Maintenance of Hippocampal Structure by MacLusky, Neil J, Hajszan, Tibor, Leranth, Csaba

“…The effects of androgens and the androgen antagonist, flutamide, on the density of dendritic spine synapses in the CA1 subfield of the hippocampus were studied…”
Get full text

Loss of asymmetric spine synapses in dorsolateral prefrontal cortex of cognitively impaired phencyclidine-treated monkeys by Elsworth, John D., Hajszan, Tibor, Leranth, Csaba, Roth, Robert H.

“…Schizophrenia patients, long-term abusers of phencyclidine (PCP), and monkeys treated with PCP all exhibit enduring cognitive deficits. Evidence indicates that…”
Get full text

Reply to Mathews: Misplaced focus on experimental detail by Leranth, Csaba, Hajszan, Tibor, MacLusky, Neil, vom Saal, Frederick

Get full text

Bisphenol A interferes with synaptic remodeling by Hajszan, Tibor, Leranth, Csaba

“…Abstract The potential adverse effects of Bisphenol A (BPA), a synthetic xenoestrogen, have long been debated. Although standard toxicology tests have revealed…”
Get full text

Stress and remodeling of hippocampal spine synapses by Hajszan, Tibor

Get full text

Distribution and origin of vesicular glutamate transporter 2-immunoreactive fibers in the rat hippocampus by Halasy, Katalin, Hajszan, Tibor, Kovács, Éva G., Lam, Thien-Tri, Leranth, Csaba

“…This study examined the distribution of vesicular glutamate transporter 2 (VGLUT2)‐immunoreactive neuronal structures in the ipsilateral and contralateral…”
Get full text

Extrinsic afferent systems to the dentate gyrus by Leranth, Csaba, Hajszan, Tibor

“…The dentate gyrus is the first stage of the intrahippocampal, excitatory, trisynaptic loop, and a primary target of the majority of entorhinal afferents that…”
Get more information

Stress Resilience is Associated with Hippocampal Synaptoprotection in the Female Rat Learned Helplessness Paradigm by Huzian, Orsolya, Baka, Judith, Csakvari, Eszter, Dobos, Nikoletta, Leranth, Csaba, Siklos, Laszlo, Duman, Ronald S., Farkas, Tamas, Hajszan, Tibor

“…•Helpless behavior of female rats is associated with the loss of hippocampal spine synapses.•Diazepam strongly prevents the development of helpless behavior…”
Get full text

Expression of Estrogen Receptor-β Messenger Ribonucleic Acid in Oxytocin and Vasopressin Neurons of the Rat Supraoptic and Paraventricular Nuclei by Hrabovszky, Erik, Kalló, Imre, Hajszán, Tibor, Shughrue, Paul J., Merchenthaler, István, Liposits, Zsolt

“…Abstract The regulatory actions of estrogen on magnocellular oxytocin (OT) and vasopressin (VP) neurons of the paraventricular (PVN) and supraoptic (SON)…”
Get full text

Stress induces equivalent remodeling of hippocampal spine synapses in a simulated postpartum environment and in a female rat model of major depression by Baka, Judith, Csakvari, Eszter, Huzian, Orsolya, Dobos, Nikoletta, Siklos, Laszlo, Leranth, Csaba, MacLusky, Neil J, Duman, Ronald S, Hajszan, Tibor

“…Highlights • Postpartum stress causes a loss of hippocampal spine synapses. • Pregnancy levels of ovarian hormones prevent the synaptolytic effect of stress. •…”
Get full text

Short-term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus by Hajszan, Tibor, MacLusky, Neil J., Leranth, Csaba

“…The pathomechanism of major depressive disorder and the neurobiological basis of antidepressant therapy are still largely unknown. It has been proposed that…”
Get full text