Search Results - "Hajiasgharzadeh, Khalil"
-
1
PD‐1/PD‐L1‐dependent immune response in colorectal cancer
Published in Journal of cellular physiology (01-07-2020)“…Colorectal cancer (CRC) is still considered as the third most frequent cancer in the world. Microsatellite instability (MSI), inflammation, and microRNAs have…”
Get full text
Journal Article -
2
Regulatory mechanisms of microRNAs in colorectal cancer and colorectal cancer stem cells
Published in Journal of cellular physiology (01-02-2020)“…Colorectal cancer (CRC) is one of the most lethal and hard‐to‐treat cancers in the world, which in its advanced stages, surgery and chemotherapy are the main…”
Get full text
Journal Article -
3
Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death
Published in Cancers (23-04-2020)“…Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is increasing the susceptibility of cells to death. Cancer cells…”
Get full text
Journal Article -
4
The potential role of miR‐29 in health and cancer diagnosis, prognosis, and therapy
Published in Journal of cellular physiology (01-11-2019)“…miR‐29 family is one of the small noncoding RNAs and has a very important role in many physiologic and pathologic functions through regulating the target genes…”
Get full text
Journal Article -
5
Overcoming trastuzumab resistance in HER2‐positive breast cancer using combination therapy
Published in Journal of cellular physiology (01-04-2020)“…Human epidermal growth factor receptor 2 (HER2)‐positive breast cancer (BC) comprises around 20–30% of all BC subtypes and is correlated with poor prognosis…”
Get full text
Journal Article -
6
The role of HSP90 molecular chaperones in hepatocellular carcinoma
Published in Journal of cellular physiology (01-12-2020)“…Misfolded proteins have enhanced formation of toxic oligomers and nonfunctional protein copies lead to recruiting wild‐type protein types. Heat shock protein…”
Get full text
Journal Article -
7
Small interfering RNA–mediated gene suppression as a therapeutic intervention in hepatocellular carcinoma
Published in Journal of cellular physiology (01-04-2019)“…Hepatocellular carcinoma (HCC) is one of the lethal and difficult‐to‐cure cancers worldwide. Owing to the late diagnosis and drug resistance of malignant…”
Get full text
Journal Article -
8
Immune Checkpoints and CAR-T Cells: The Pioneers in Future Cancer Therapies?
Published in International journal of molecular sciences (05-11-2020)“…Although the ever-increasing number of cancer patients pose substantial challenges worldwide, finding a treatment with the highest response rate and the lowest…”
Get full text
Journal Article -
9
Alpha7 nicotinic acetylcholine receptors in lung inflammation and carcinogenesis: Friends or foes?
Published in Journal of cellular physiology (01-09-2019)“…The lung tissue expresses the cholinergic system including nicotinic acetylcholine receptors (nAChRs) which included in many physiologic and pathologic…”
Get full text
Journal Article -
10
CTLA-4: As an Immunosuppressive Immune Checkpoint in Breast Cancer
Published in Current molecular medicine (01-01-2023)“…Breast cancer (BC) is one of the prevalent diseases and causes of death in women, and its incidence rate is increasing in numerous developed and developing…”
Get more information
Journal Article -
11
Effects of nicotine on microRNA-124 expression in bile duct ligation-induced liver fibrosis in rats
Published in BMC pharmacology & toxicology (28-03-2024)“…Nicotine, the main compound of smoking may exert its effects by changing the expression of microRNAs (miRNAs). This study was conducted to further investigate…”
Get full text
Journal Article -
12
Resistance mechanisms to immune checkpoints blockade by monoclonal antibody drugs in cancer immunotherapy: Focus on myeloma
Published in Journal of cellular physiology (01-02-2021)“…Multiple myeloma (MM) is a clonal B‐cell malignancy characterized by the accumulation of neoplastic proliferation of a plasma cell in the bone marrow that…”
Get full text
Journal Article -
13
The regulatory role of autophagy-related miRNAs in lung cancer drug resistance
Published in Biomedicine & pharmacotherapy (01-04-2022)“…Autophagy is conserved cellular machinery that degrades un-usable proteins and cellular components and has a crucial role in the pathogenesis and drug…”
Get full text
Journal Article -
14
Cholinergic Anti-Inflammatory Pathway and the Liver
Published in Advanced pharmaceutical bulletin (01-12-2017)“…The inflammatory reflex For the first time, Tracey and coworkers described a previously unrecognized role of efferent vagus nerve signaling in modulating…”
Get full text
Journal Article -
15
Inflammatory reflex disruption in COVID‐19
Published in Clinical & experimental neuroimmunology (01-11-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) was identified in Wuhan, China, in late 2019 and caused coronavirus disease 2019 (COVID‐19), which…”
Get full text
Journal Article -
16
From Melanoma Development to RNA-Modified Dendritic Cell Vaccines: Highlighting the Lessons From the Past
Published in Frontiers in immunology (22-02-2021)“…Although melanoma remains the deadliest skin cancer, the current treatment has not resulted in the desired outcomes. Unlike chemotherapy, immunotherapy has…”
Get full text
Journal Article -
17
Targeted Therapy of B7 Family Checkpoints as an Innovative Approach to Overcome Cancer Therapy Resistance: A Review from Chemotherapy to Immunotherapy
Published in Molecules (Basel, Switzerland) (31-05-2022)“…It is estimated that there were 18.1 million cancer cases worldwide in 2018, with about 9 million deaths. Proper diagnosis of cancer is essential for its…”
Get full text
Journal Article -
18
A scoping review on the potentiality of PD-L1-inhibiting microRNAs in treating colorectal cancer: Toward single-cell sequencing-guided biocompatible-based delivery
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Tumoral programmed cell death ligand 1 (PD-L1) has been implicated in the immune evasion and development of colorectal cancer. Although monoclonal immune…”
Get full text
Journal Article -
19
Targeted anti-inflammatory therapy is a new insight for reducing cardiovascular events: A review from physiology to the clinic
Published in Life sciences (1973) (15-07-2020)“…Despite considerable progressions, cardiovascular disease (CVD) is still one of the major causes of mortality around the world, indicates an important and…”
Get full text
Journal Article -
20
Varied functions of immune checkpoints during cancer metastasis
Published in Cancer Immunology, Immunotherapy (01-03-2021)“…Immune checkpoints comprise diverse receptors and ligands including costimulatory and inhibitory molecules, which play monumental roles in regulating the…”
Get full text
Journal Article