Search Results - "Hajdu, Bálint"
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Benchmark ab Initio Characterization of the Complex Potential Energy Surfaces of the X– + NH2Y [X, Y = F, Cl, Br, I] Reactions
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (22-02-2018)“…We report a comprehensive high-level explicitly correlated ab initio study on the X– + NH2Y [X,Y = F, Cl, Br, I] reactions characterizing the stationary points…”
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Journal Article -
2
Structures of Silver Fingers and a Pathway to Their Genotoxicity
Published in Angewandte Chemie International Edition (14-03-2022)“…Recently, we demonstrated that AgI can directly replace ZnII in zinc fingers (ZFs). The cooperative binding of AgI to ZFs leads to a thermodynamically…”
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Journal Article -
3
Hydrolytic Mechanism of a Metalloenzyme Is Modified by the Nature of the Coordinated Metal Ion
Published in Molecules (Basel, Switzerland) (19-07-2023)“…The nuclease domain of colicin E7 cleaves double-strand DNA non-specifically. Zn ion was shown to be coordinated by the purified NColE7 as its native metal…”
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Journal Article -
4
Zinc binding of a Cys2His2-type zinc finger protein is enhanced by the interaction with DNA
Published in Journal of biological inorganic chemistry (01-04-2023)“…Zinc finger proteins specifically recognize DNA sequences and, therefore, play a crucial role in living organisms. In this study the Zn(II)-, and DNA-binding…”
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Journal Article -
5
Estradiol-Based Salicylaldehyde (Thio)Semicarbazones and Their Copper Complexes with Anticancer, Antibacterial and Antioxidant Activities
Published in Molecules (Basel, Switzerland) (21-12-2022)“…A series of novel estradiol-based salicylaldehyde (thio)semicarbazones ((T)SCs) bearing (O,N,S) and (O,N,O) donor sets and their Cu(II) complexes were…”
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Journal Article -
6
Interactions of an Artificial Zinc Finger Protein with Cd(II) and Hg(II): Competition and Metal and DNA Binding
Published in Inorganics (01-02-2023)“…Cys2His2 zinc finger proteins are important for living organisms, as they—among other functions—specifically recognise DNA when Zn(II) is coordinated to the…”
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Journal Article -
7
Algal cell response to laboratory-induced cadmium stress: a multimethod approach
Published in European biophysics journal (01-04-2019)“…We examined the response of algal cells to laboratory-induced cadmium stress in terms of physiological activity, autonomous features (motility and…”
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Journal Article -
8
Circular Dichroism Spectroscopic Studies on Solution Chemistry of M(II)-Monensinates in Their Competition Reactions
Published in Inorganics (01-08-2023)“…The chirality of the polyether ionophore monensic acid A can be successfully used to study its coordination ability in solution. A complementary approach to…”
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Journal Article -
9
Nickel(ii)-promoted specific hydrolysis of zinc finger proteins
Published in Metallomics (15-08-2018)“…In this work we demonstrate that the previously described reaction of sequence specific Ni(ii)-dependent hydrolytic peptide bond cleavage can be performed in…”
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Journal Article -
10
The coordination modes of (thio)semicarbazone copper(II) complexes strongly modulate the solution chemical properties and mechanism of anticancer activity
Published in Journal of inorganic biochemistry (01-06-2022)“…Thiosemicarbazones are promising candidates for anticancer therapy and their mechanism of action is often linked to their metal chelating ability. In this…”
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Journal Article -
11
Benchmark ab Initio Characterization of the Complex Potential Energy Surfaces of the X - + NH 2 Y [X, Y = F, Cl, Br, I] Reactions
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (22-02-2018)“…We report a comprehensive high-level explicitly correlated ab initio study on the X + NH Y [X,Y = F, Cl, Br, I] reactions characterizing the stationary points…”
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Journal Article -
12
Modulation of the catalytic activity of a metallonuclease by tagging with oligohistidine
Published in Journal of inorganic biochemistry (01-05-2020)“…Peptide tags are extensively used for affinity purification of proteins. In an optimal case, these tags can be completely removed from the purified protein by…”
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Journal Article -
13
Purification of proteins with native terminal sequences using a Ni(II)-cleavable C-terminal hexahistidine affinity tag
Published in Protein expression and purification (01-07-2019)“…The role of the termini of protein sequences is often perturbed by remnant amino acids after the specific protease cleavage of the affinity tags and/or by the…”
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Journal Article -
14
Interactions of an Artificial Zinc Finger Protein with Cd: Competition and Metal and DNA Binding
Published in Inorganics (01-01-2023)“…Cys2His2 zinc finger proteins are important for living organisms, as they—among other functions—specifically recognise DNA when Zn(II) is coordinated to the…”
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Journal Article -
15
Cinkujj fehérjék fémion- és DNS-kötésének vizsgálata, módosításuk Ni(II)-indukált peptidhidrolízis segítségével
Published 01-01-2023“…Doktori munkám során a Ni(II)-indukált peptidhidrolízist és annak alkalmazási lehetőségeit tanulmányoztam főként cinkujj fehérjéket felhasználva, valamint…”
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Dissertation -
16
Structures of Silver Fingers and a Pathway to Their Genotoxicity
Published in Angewandte Chemie (14-03-2022)“…Recently, we demonstrated that AgI can directly replace ZnII in zinc fingers (ZFs). The cooperative binding of AgI to ZFs leads to a thermodynamically…”
Get full text
Journal Article -
17
Nickel(ii)-promoted specific hydrolysis of zinc finger proteinsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8mt00098k
Published 15-08-2018“…In this work we demonstrate that the previously described reaction of sequence specific Ni( ii )-dependent hydrolytic peptide bond cleavage can be performed in…”
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Journal Article